As sementes do gênero Crotalaria L., de um modo geral, apresentam dificuldades no processo germinativo. O objetivo da pesquisa foi avaliar a eficiência do extrato bruto de Brunfelsia uniflora na germinação de Crotalaria spectabilis. O delineamento foi inteiramente casualizado, com quatro tratamentos ...
Abstract The aim of this study was to evaluate the effect of green tea as a protective measure on eroded dentin. Disks of human coronary dentin were selected based on surface hardness and randomly assigned to 3 groups (n = 10): DW - distilled water, CHX - 0.2% chlorhexidine digluconate, and GT - green te...
Análisis de Varianza,
Clorhexidina/análogos & derivados,
Clorhexidina/química,
Dentina/efectos de los fármacos,
Dureza,
Metaloproteinasas de la Matriz/química,
Extractos Vegetales/química,
Sustancias Protectoras/química,
Distribución Aleatoria,
Reproducibilidad de los Resultados,
Saliva Artificial/química,
Estadísticas no Paramétricas,
Propiedades de Superficie/efectos de los fármacos,
Té/química,
Factores de Tiempo,
Erosión de los Dientes/prevención & control,
Agua/química
Schmitt, Gabriela Cristina;
Arbo, Marcelo Dutra;
Lorensi, Andréia Louise;
Jacques, Ana Laura Bemvenuti;
Nascimento, Sabrina Nunes do;
Mariotti, Kristiane de Cássia;
Garcia, Solange Cristina;
Dallegrave, Eliane;
Leal, Mirna Bainy;
Limberger, Renata Pereira.
ABSTRACT The association of p-synephrine, ephedrine, salicin, and caffeine in dietary supplements and weight loss products is very common worldwide, even though ephedrine has been prohibited in many countries. The aim of this study was to evaluate a 28-day oral exposure toxicity profile of p-synephrine, ...
ABSTRACT Indigofera linnaei Ali. (Tamil Name: Cheppu Nerinjil) belongs to the family Fabaceae, used for the treatment of various ailments in the traditional system of medicine. In the present study, the beneficial effects of methanol extract of whole plant of I. linnaei (MEIL) were evaluated on inflammat...
ABSTRACT Azithromycin is a water-insoluble drug, with a very low bioavailability. In order to increase the solubility and dissolution rate, and consequently increase the bioavailability of poorly-soluble drugs (such as azithromycin), various techniques can be applied. One of such techniques is "solid dis...
Andréo, Marcio Adriano;
Rufino, Iasmin Mimoto;
Ubaldo, Daniela Cecilia Ortiz de Orue;
Herbst, Estela Boaro;
Silva, Heron Dominguez Torres da;
Oliveira, Pedro Gonçalves de;
Ferrari, Marcio;
Rosa, Paulo Cesar Pires;
Lopes, Patrícia Santos;
Leite-Silva, Vânia Rodrigues.
ABSTRACT Aiming to alter and/or improve permeation of active compounds in the skin, many strategies have been developed, including biophysical methods. One of the physical absorption techniques, currently known as Cryo Laser Phoresis (CLP), consists of an apparatus that emits radiation on polar or nonpol...
ABSTRACT This study evaluated the influence of glucose and stirring in the fermentation process in order to produce anti-Candida metabolites produced by Streptomyces sp. MPO4 isolated from Amazon soil. The anti-Candida metabolites production was registered after 24 h of fermentation in stirred ISP2 mediu...
ABSTRACT This study aimed to obtain and characterize a microemulsion (ME) containing phenobarbital (PB). The PB was incorporated in the proportion of 5% and 10% in a microemulsion system containing Labrasol(r), ethanol, isopropyl myristate and purified water. The physicochemical characterization was perf...
ABSTRACT Recent advances in drug delivery systems have aimed to achieve better patient compliance. One of these advances is the formulation of orally disintegrating tablets (ODTs) that dissolve instantaneously, releasing drugs within a few seconds without the need of water. The main objective of this pap...
Ren, Yachao;
Jiang, Lei;
Yang, Shuman;
Gao, Sainan;
Yu, Hui;
Hu, Jie;
Hu, Dandan;
Mao, Wenbin;
Peng, Haisheng;
Zhou, Yulong.
ABSTRACT The objective of this research was to design a new colon-targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composite films were used in a bilayer system to investigate the...
