Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Disease...
Introducción. La enfermedad de Chagas es causada por el parásito Trypanosoma cruzi, se transmite cuando las heces infectadas de vectores triatomineos tienen contacto con el huésped por medio de una picadura o a través de una membrana mucosa; otras vías de infección incluyen transfusio...
Para la Sociedad de Cirugía de Bogotá, Hospital de San José, es un honor haber contado con la presencia del doctor Josep Brugada en el marco del Segundo Simposio SDC, muerte súbita cardiovascular, del proyecto PR-Chagas, financiado por Colciencias y organizado en conjunto con docentes de la Fundació...
Pavão, Beatriz Philot;
Demarque, Kelly Cristina;
Batista, Marcos Meuser;
Oliveira, Gabriel Melo de;
Silva, Cristiane França da;
Silva, Francisca Hildemagna Guedes da;
Caputo, Luzia Fátima Gonçalves;
Cascabulho, Cynthia Machado;
Barcinski, Marcello André;
Soeiro, Maria de Nazaré Correia.
Autologous whole blood (AWB) administration is described as alternative/complementary medical practice widely employed in medical and veterinary therapy against infections, chronic pathologies and neoplasias. Our aim is to investigate in vivo biological effect of AWB using healthy murine models under the...
BACKGROUND Chagas disease is highly prevalent in Latin America, and vector control is the most effective control strategy to date. We have previously shown that liquid chromatography tandem mass spectrometry (LC-MS/MS) is a valuable tool for identifying triatomine vector blood meals. OBJECTIVES The pu...
Apesar do declínio na prevalência da doença de Chagas no Brasil, a Região Nordeste apresenta condições propícias ao seu recrudescimento. O objetivo deste estudo foi analisar a positividade por doença de Chagas entre doadores de sangue do Piauí entre 2004 e 2013. A prevalência de sorologia reage...
ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprec...
BACKGROUND Trypanosoma cruzi is a protozoan parasite and an etiological agent of Chagas disease. There is a wide variability in the clinical outcome of its infection, ranging from asymptomatic individuals to those with chronic fatal mega syndromes. Both parasite and host factors, as well as their interpl...
BACKGROUND Transforming growth factor β1 (TGF-β1) and tumour necrosis factor (TNF) have been implicated in Chagas disease pathophysiology and may correlate with left ventricular (LV) function. OBJECTIVES We determined whether TGF-β1 and TNF serum levels correlate with LV systolic and di...
ABSTRACT Background: Researches on Chagas disease still use several animals and rats, due to size and susceptibility were preferred by many authors. Aim: To develop an experimental model of megacolon in rats inoculated with the strain Y of Trypanosoma cruzi. Methods: Thirty male Wistar rats were dis...
