Results: 428
Fabrication and in vitro characterization of polymeric nanoparticles for Parkinson's therapy: a novel approach
Braz. j. pharm. sci; 50 (4), 2014
The objective of the research was to formulate and evaluate selegiline hydrochloride loaded chitosan nanoparticles for the Parkinson's therapy in order to improve its therapeutic effect and reducing dosing frequency. Taguchi method of design of experiments (L9 orthogonal array) was used to get optimized ...
Comparison of the antioxidant potential of antiparkinsonian drugs in different in vitro models
Braz. j. pharm. sci; 50 (4), 2014
Parkinson's disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta. Furthermore, oxidative stress plays a role in PD, causing or contributing to the neurodegenerative process. Currently PD has only symptomatic treatment and still nothing ca...
Memória evocativa em pacientes não dementes com doença de Parkinson
Rev. bras. neurol; 49 (3), 2013
INTRODUÇÃO: A doença de Parkinson (DP) é uma moléstia neuro-psiquiátrica caracterizada principalmente por manifestação motora - tremor de repouso, bradicinesia, rigidez e alterações do equilíbrio. No fim do século XIX, observou-se também comprometimento cognitivo na DP. Entre as alterações...
Influência do fortalecimento muscular na independência funcional de indivíduos parkinsonianos
Conscientiae saúde (Impr.); 12 (3), 2013
La pluralidad temática qué caracteriza a Anales de la Facultad de Medicina, permite que la revista pueda ofrecer un menú muy variado de temas que van de la investigación experimental, la investigación clínica, estudios sobre comportamientos de estudiantes de medicina y aspectos relacionadas a la educación médica, entre otros.. [Editorial]
An. Fac. Med. (Perú); 74 (3), 2013
Dysphagia and sialorrhea
Arq. gastroenterol; 50 (1), 2013
ContextDysphagia and sialorrhea in patients with Parkinson's disease are both automatically accepted as dependent on this neurological disease.ObjectiveThe aim were to establish if these two complaints are a consequence or associated manifestations of Parkinson's disease.MethodTwo Parkinson's diseases gr...
Estudo da influência positiva na qualidade de vida de portadores da Doença de Parkinson participantes do Grupo Lótus
Rev. Kairós; 15 (4), 2012
O portador de doença de Parkinson sofre alterações sensório-motoras e emocionais. O objetivo deste estudo é identificar os benefícios na qualidade de vida de idosos que participam de oficinas diversas e muito adequadas, oferecidas pelo Grupo Lótus - Associação Parkinson da Baixada Santista, tent...
Neuropsychological and quality of life assessment in patients with Parkinsons disease submitted to bilateral deep brain stimulation in the subthalamic nucleus
Dement. neuropsychol; 6 (4), 2012
Deep brain stimulation (DBS) has been widely used to control motor symptoms and improve quality of life inpatients with Parkinsons disease (PD). Recently, DBS in the subthalamic nucleus (STN) has become the preferred targetfor patients with mixed motor symptoms. Despite resultant motor and quality of lif...
Efetividade da fisioterapia associada à musicoterapia na doença de Parkinson
Conscientiae saúde (Impr.); 11 (4), 2012