Results: 5032

High-level soluble expression of the functional peptide derived from the C-terminal domain of the sea cucumber lysozyme and analysis of its antimicrobial activity

Electron. j. biotechnol; 17 (6), 2014
Background The sea cucumber lysozyme belongs to the family of invertebrate lysozymes and is thought to be a key defense factor in protecting aquaculture animals against bacterial infection. Recently, evidence was found that the sea cucumber lysozyme exerts broad spectrum antimicrobial action in vitro aga...

Induction of corneal collagen cross-linking in experimental corneal alkali burns in rabbits

Arq. bras. oftalmol; 77 (5), 2014
Objective: To evaluate the effect of riboflavin-ultraviolet-A-induced cross-linking (CXL) following corneal alkali burns in rabbits. Methods: The right corneas and limbi of ten rabbits were burned using a 1N solution of NaOH and the animals were then divided into two groups: a control group submitted to ...

Analgesia preemptiva com nepafenaco 0, 1% na fotocoagulação da retina

Rev. bras. oftalmol; 73 (5), 2014
Objetivo: Avaliar o efeito preemptivo com nepafenaco 0,1% em pacientes submetidos à fotocoagulação da retina para tratamento da retinopatia diabética proliferativa. Métodos: Trinta pacientes foram submetidos à fotocoagulação com laser de argônio em ambos os olhos. O olho contralateral de cada pa...

The effects of supraphysiological supplementation of b-carotene in spontaneously hypertensive rats (SHR and SHR-sp)

Rev. Col. Bras. Cir; 41 (5), 2014
Objective: to investigate the effect of administration of supraphysiological âcaroteno on biological parameters (ectoscopy and blood pressure), laboratory (malondialdehyde) and histological (liver and carotid arteries) of spontaneously hypertensive rats prone to stroke (SHR-sp). Methods: we used 36 male...

Metformin induces ultrastructural alterations in hepatocytes of spontaneously hypertensive rats

Int. j. morphol; 32 (3), 2014
Metformin, an oral biguanide approved for the treatment of type II diabetes is widely prescribed for other clinical conditions. Currently, metformin is being investigated as potential anti-tumor agent. However, there have been recent concerns about hepatotoxicity associated with the use of metformin. Thi...

The effect of walnut on the weight, blood glucose and sex hormones of diabetic male rats

Int. j. morphol; 32 (3), 2014
Diabetes leads to reproductive dysfunctions by producing free radicals. It seems that using walnut can be effective in the damage induced by diabetes. The aim of the present study was to evaluate the effects of walnut consumption on sex hormones in diabetic Wistar male rats induced by STZ (streptozotocin...

Effects of biodegradable detergents in the accumulation of lipofuscin (age pigment) in gill and liver of two neotropical fish species

Int. j. morphol; 32 (3), 2014
Currently there is a growing concern, in both population and governments, to identify the effects of substances commonly disposed of into rivers and lakes, on aquatic fauna and flora. Thus the objective of the present study was to verify effects of biodegradable detergents and water from an urban lake on...

Protective effect of curcumin against nicotine-induced damage on reproductive parameters in male mice

Int. j. morphol; 32 (3), 2014
Nicotine consumption can decrease fertility drive in males through inducing oxidative stress and DNA damage. The color of turmeric is because of a substance called curcumin for which some anti-oxidative and anti-inflammatory properties have been identified. In this study, various doses of curcumin (10, 3...

Morphometrical analysis of the effect of nicotine administration on brain's prefrontal region in male rat

Int. j. morphol; 32 (3), 2014
Nicotine is the most important alkaloid compound in tobacco. One of the major effects of nicotine is stimulation of mesocorticolimbic system. Prefrontal cortex plays a pivotal role in personality and mental state. It is considered the main cause of addiction as it is located in mesocorticolimbic dopamine...

Histomorphometric evaluation of soleus and lateral gastrocnemius muscles of animals submitted to pharmacological manipulation with fluoxetine

Int. j. morphol; 32 (3), 2014
The pharmacological manipulation with selective inhibitor of serotonin reuptake (SSRIs) can modify the operation of the serotonergic system and may facilitate or inhibit the action of this system, inducing changes in the morphology of the skeletal muscle of rats. The objective of this study was to evalua...