Results: 723

Modulación de marcadores de inflamación y estrés oxidativo en pacientes con diabetes tipo 1 y sobrepeso que participan en un programa de cambio de estilo de vida

Introduction: Reduction in the expression of inflammatory markers and oxidative stress associated with exercise will protect against cardiovascular complications in Diabetes Mellitus (DM). Aim: The aim of this study was evaluated cardiovascular fitness (VO2 Max), interleukin-6 (IL-6), monocyte chemo-attr...

Alprostadil attenuates myocardial ischemia/reperfusion injury by promoting antioxidant activity and eNOS activation in rats

Acta cir. bras; 33 (12), 2018
Abstract Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion. Alprostadil (4 or 8 μg/kg) was intravenously administered at the time of reperfusion and myocar...

Mecanismos involucrados en la fragilidad ósea en diabetes mellitus
Mechanisms involved in the bone fragility in diabetes mellitus

Actual. osteol; 14 (3), 2018
La diabetes es una enfermedad crónica asociada con importantes comorbilidades. El sistema esquelético parece ser un objetivo adicional de daño mediado por diabetes. Se acepta que la diabetes tipo 1 y tipo 2 se asocian con un mayor riesgo de fractura ósea. Varios estudios han demostrado que los cambio...

Biochemical responses, blood gas, oxidative stress and lipid peroxidation of goats transfused with fresh or stored whole homologous blood

Pesqui. vet. bras; 38 (11), 2018
Blood transfusion is a therapeutic procedure of great importance for veterinary medicine, in spite of only few studies in the literature on hemotherapy in goats. We aimed to evaluate the biochemical, blood gas, oxidative stress and lipid peroxidation of goats submitted to homologous transfusion of fresh ...

Efectividad del Vimang® en pacientes con lesión hepática a causa del virus del dengue
Effectiveness of the Vimang® in patients with liver damage due to dengue virus

Medisan; 22 (8), 2018
Introducción: En la evolución de la infección por el virus de dengue es frecuente la aparición de la lesión hepática, lo cual se asocia con el estrés oxidativo. Objetivo: Demostrar la efectividad del concentrado de Vimang® en pacientes con diagnóstico de lesión hepática por virus del dengue...

Evaluation of redox profiles in exogenous subclinical hyperthyroidism at two different levels of TSH suppression

ABSTRACT Objective: Evaluate the relationship between exogenous subclinical hyperthyroidism and oxidative stress through the analysis of the redox profile of patients with subclinical hyperthyroidism exogenous (SCH) grade I (TSH = 0.1 to 0.4 IU/mL) and grade II (TSH < 0.1 IU/mL). Subjects and method...

Protective effects of Polygonatum sibiricum polysaccharide on acute heart failure in rats

Acta cir. bras; 33 (10), 2018
Abstract Purpose: To investigate the protective effects of Polygonatum sibiricum polysaccharide (PSP) on acute heart failure (AHF) in rats. Methods: Sixty rats were randomly divided into control, model, and low-, middle- and high-dose PSP groups, 12 rats in each group. The low-, medium- and high-dose...

Physical exercise improves body weight gain and liver function in malnourished rats without disturbing the redox balance

Rev. Nutr. (Online); 31 (5), 2018
ABSTRACT Objective To study the relationship between exercise and malnourishment because recent evidence suggests that exercise can cause the beneficial adaptation of antioxidant systems, whereas malnourishment can cause harmful adaptation of these systems. Methods Thirty-two female Fischer rats were e...

Oxidative stress and sex difference in liver of rats exposed to cyclohexanone

Int. j. morphol; 36 (3), 2018
Cyclohexanone is widely used in industry for the organic synthesis of chemicals such as adipic acid, caprolactam, polyvinyl chloride and its copolymers, and methacrylate ester polymers. Its mechanism of toxicity, especially oxidative stress, is rarely reported in cyclohexanone toxicity studies. In this s...

Metformin protects against thioacetamide induced liver injury in rats

Int. j. morphol; 36 (3), 2018
Potent heptatotoxic chemicals such as carbon tetrachloride and thioacetamide (TAA) are used to evaluate hepatoprotective agents. Here we sought to investigate the potential protective effect of the antidiabetic and antioxidant drug, metformin against liver injury induced by TAA. Model group rats received...