Background: For the crossbreeding of Auricularia auricula-judae, selecting the appropriated parents in hybridization is very important. However, the classification and diversity analysis of A. auricula-judae has been equivocal, due to the similarity of the fruiting body morphology and its susceptibility ...
La enfermedad de Parkinson es un desorden neurodegenerativo complejo, caracterizado por la pérdida progresiva de las neuronas dopaminérgicas de la sustancia nigra pars compacta. Factores tanto ambientales como genéticos se ha determinado que contribuyen a su desarrollo. Mutaciones en los genes PINK1 y...
Duplicação genica é uma das principais forças levando a evolução dos genomas eucarioto. O impacto de duplicações gênicas/genômicas vem sendo investigado a muito tempo em humanos e outros primatas. Um segundo mecanismo de duplicação gênica, a retrotransposição baseada em RNA maduros, vem se...
The aim of this study was to evaluate two important aspects of patent applications of crystalline forms of drugs: (i) the physicochemical characterization of the crystalline forms; and (ii) the procedure for preparing crystals of the blockbuster drug clopidogrel. To this end, searches were conducted usin...
Carbamazepine (CBZ), a widely used anticonvulsant drug, can crystallize and exhibits four polymorphic forms and one dihydrate. Anhydrous CBZ can spontaneously absorb water and convert to the hydrate form whose different crystallinity leads to lower biological activity. The present study was concerned to ...
BACKGROUND: Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed. We categorized 98 asthma patients acco...
Asma/genética,
Polimorfismo Genético/genética,
Proteínas ADAM/análisis,
Proteínas ADAM/genética,
Desintegrinas/análisis,
Desintegrinas/genética,
Volumen Espiratorio Forzado/genética,
Interleucina-13/análisis,
Interleucina-13/genética,
Interleucina-4/análisis,
Interleucina-4/genética,
Proteínas de Neoplasias/análisis,
Proteínas de Neoplasias/genética,
Polimorfismo de Nucleótido Simple/genética,
Receptores Adrenérgicos beta 2/análisis,
Receptores Adrenérgicos beta 2/genética,
Factor de Transcripción STAT6/análisis,
Factor de Transcripción STAT6/genética,
Capacidad Vital/genética,
Biomarcadores,
Estudios de Casos y Controles,
Genotipo,
Portugal,
Factores de Riesgo,
Índice de Severidad de la Enfermedad,
Estadísticas no Paramétricas
Background: Genetic and epigenetic changes (DNA methylation) were examined in the tissue-culture propagated interspecific potato somatic hybrids between dihaploid Solanum tuberosum and S. pinnatisectum. Amplified fragment length polymorphism (AFLP) and methylation-sensitive amplified polymorphism (MSAP) ...
Solanum tuberosum/genética,
Variación Genética,
Epigenómica,
Técnicas In Vitro,
Metilación de ADN,
Polimorfismo Genético,
Análisis del Polimorfismo de Longitud de Fragmentos Amplificados,
Solanum tuberosum/crecimiento & desarrollo,
ADN/aislamiento & purificación,
Hibridación Genética,
ADN de Plantas
Background: The object of this work was to determine the genetic and allelic diversity of Solanum species present in Chile, assessing allelic distribution among native varieties and commercial cultivars of Solanum tuberosum ssp. tuberosum L., using microsatellite markers. Results: A high level of allelic...
Background: Broccoli, Brassica oleracea subsp. italica is one of the many valuable Brassica species which is still less cultured under in vitro condition. Heat tolerant transgenic and non-transgenic broccoli cv. Green Marvel plantlets with well-developed root system obtained through in vitro culture were...
Brassica/genética,
Brassica/metabolismo,
Invernaderos,
Variación Genética,
Repeticiones de Microsatélite,
Plantas Modificadas Genéticamente,
Técnicas In Vitro,
Polimorfismo Genético,
Filogenia,
Termotolerancia,
Proteínas de Choque Térmico/genética
