A esterilização química é uma técnica de esterilização que consiste na aplicação intratesticular de agentes esclerosantes, com o intuito de causar dano ao tecido testicular e, consequentemente, suprimir a atividade reprodutiva em animais do sexo masculino. Por ser uma técnica de rápida execuç...
Atualmente, o uso indiscriminado de antimicrobianos tem contribuído para o aparecimento de microrganismos resistentes, pois, os mesmos ao entrarem em contato com o princípio ativo dessas drogas de forma indevida, desenvolvem características fisiológicas e genéticas tais como a mutação de seu DNA, ...
Conservar alimentos na forma de silagem possui grande valia em regiões que ocorre estacionalidade climática, onde o excedente de forragem produzido no período das águas poderá ser utilizado posteriormente na época de estiagem. Para se produzir silagem de qualidade é preciso atentar-se para vários...
Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: Bth...
Oliveira, Camila Franco Batista;
Alves, Daniela Pereira;
Emerich, Bruna Luiza;
Figueiredo, Suely Gomes de;
Cordeiro, Marta do Nascimento;
Borges, Márcia Helena;
Richardson, Michael;
Pimenta, Adriano Monteiro de Castro;
Duarte, Igor Dimitri Gama;
Lima, Maria Elena de.
The venom of Phoneutria nigriventer spider is a source of numerous bioactive substances, including some toxins active in insects. An example is PnTx4(5-5) that shows a high insecticidal activity and no apparent toxicity to mice, although it inhibited NMDA-evoked currents in rat hippocampal neurons. In th...
Abstract The objective of the present study was to produce wine from wild edible fruits of Flacourtia montana J. Graham. The various physicochemical attributes including total phenolic content and total flavonoid content were analyzed. Further, the prepared wine was evaluated for the antioxidant potentia...
Several studies have pointed out that certain snake venoms contain compounds presenting cytotoxic activities that selectively interfere with cancer cell metabolism. In this study, Pseudocerastes persicus venom and its fractions were investigated for their anticancer potential on lung cancer cells. Metho...
Wolf cichlid, Parachromis dovii, is a species with a high potential for aquaculture in Central America; however, the knowledge of the digestive physiology in larvae period is limited. For these reason, this study evaluated the changes on digestive enzymes (alkaline and acid proteases, trypsin, chymotryps...
ABSTRACT In order for the use of biological carotenoids to become feasible, it is necessary to have adequate low cost sources and improved methods of cultivation. The aim of this study was to evaluate the effect of supplementation with nitrogen, phosphorus, zinc, and magnesium, on the biomass and caroten...
Biomasa,
Carotenoides/biosíntesis,
Medios de Cultivo/síntesis química,
Medios de Cultivo/química,
Medios de Cultivo/metabolismo,
Nitrógeno/metabolismo,
Rhodotorula/genética,
Rhodotorula/crecimiento & desarrollo,
Rhodotorula/metabolismo,
Saccharum/metabolismo,
Saccharum/microbiología
Abstract Purpose: To establish a method for the preparation of zoledronate liposome and to observe its effect on inducing the apoptosis of rat liver Kupffer cells. Methods: Zoledronate was encapsulated in liposomes, and then the entrapment rate was detected on a spectrophotometer. The prepared Zoledro...
Apoptosis/efectos de los fármacos,
Recuento de Células,
Composición de Medicamentos/métodos,
Citometría de Flujo,
Inmunohistoquímica,
Macrófagos del Hígado/efectos de los fármacos,
Liposomas/síntesis química,
Hígado/citología,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Reproducibilidad de los Resultados,
Resultado del Tratamiento,
Ácido Zoledrónico/administración & dosificación,
Ácido Zoledrónico/síntesis química,
Ácido Zoledrónico/farmacología
