Malaria and tuberculosis are no longer considered to be neglected diseases by the World Health Organization. However, both are huge challenges and public health problems in the world, which affect poor people, today referred to as neglected populations. In addition, malaria and tuberculosis present the s...
Abstract Tuberculosis is one of the most common infections worldwide with particularly high incidence rates in countries with unfavorable socioeconomic conditions and among persons with impaired immune systems. While most patients with this disease will present with pulmonary tuberculosis, immunocompromi...
ABSTRACT OBJECTIVES To calculate the rate of tuberculosis cases per prison unit in Espírito Santo; present the individual, clinical, and institutional characteristics of the cases in persons deprived of liberty (PPL); and analyze the association between these characteristics and treatment outcome in t...
Antituberculosos/uso terapéutico,
Brasil,
Libertad,
Accesibilidad a los Servicios de Salud,
Prisioneros/estadística & datos numéricos,
Prisiones,
Resultado del Tratamiento,
Tuberculosis/diagnóstico,
Tuberculosis/tratamiento farmacológico,
Tuberculosis/epidemiología,
Tuberculosis Resistente a Múltiples Medicamentos
ABSTRACT Given the global burden of tuberculosis, shortened treatment regimens with existing or repurposed drugs are needed to contribute to tuberculosis control. The long duration of treatment of drug-susceptible tuberculosis (DS-TB) is associated with nonadherence and loss to follow up, and the treatme...
Mancuzo, Eliane Viana;
Martins Netto, Eduardo;
Sulmonett, Nara;
Viana, Vanessa de Souza;
Croda, Júlio;
Kritski, Afranio Lineu;
Mello, Fernanda Carvalho de Queiroz;
Nihues, Simone de Souza Elias;
Azevedo, Karen Rosas Sodre;
Miranda, Silvana Spíndola de.
ABSTRACT Objective: To compare patients with and without previous lung disease, in terms of the spirometry results after they had been treated for pulmonary tuberculosis (PTB) and cured, as well as to analyze risk factors related to functional severity. Methods: This was a cross-sectional, multicenter ...
Antituberculosos/uso terapéutico,
Brasil,
Estudios de Casos y Controles,
Estudios Transversales,
Pulmón/diagnóstico por imagen,
Pulmón/microbiología,
Pulmón/fisiopatología,
Enfermedades Pulmonares/diagnóstico,
Enfermedades Pulmonares/fisiopatología,
Pruebas de Función Respiratoria/métodos,
Índice de Severidad de la Enfermedad,
Fumar/efectos adversos,
Espirometría/estadística & datos numéricos,
Tuberculosis Pulmonar/complicaciones,
Tuberculosis Pulmonar/diagnóstico por imagen,
Tuberculosis Pulmonar/tratamiento farmacológico
ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospita...
Antituberculosos/farmacología,
Antituberculosos/uso terapéutico,
Brasil/epidemiología,
Estudios Transversales,
Pruebas de Sensibilidad Microbiana,
Mycobacterium tuberculosis/efectos de los fármacos,
Centros de Atención Terciaria,
Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico,
Tuberculosis Resistente a Múltiples Medicamentos/tratamiento farmacológico,
Tuberculosis Resistente a Múltiples Medicamentos/epidemiología,
Tuberculosis Pulmonar/tratamiento farmacológico,
Tuberculosis Pulmonar/epidemiología,
Tuberculosis Pulmonar/microbiología
Resumen La peritonitis tuberculosa es una entidad infrecuente en la población pediátrica. Es una forma poco común de tuberculosis extrapulmonar y representa un muy bajo porcentaje de todos los casos de tuberculosis. Sus síntomas son inespecíficos, manifestándose usualmente con ascitis, dolor abdomi...
Resumo Objetivo: Descrever aspectos clínicos e esquema terapêutico dos pacientes com tuberculose ocular presumida tratados em um centro de referência em tuberculose de São Paulo. Métodos: Estudo retrospectivo descritivo. O teste exato de Fisher foi realizado quando apropriado. Resultados: A queix...
Tuberculosis Ocular/tratamiento farmacológico,
Tuberculosis Ocular/diagnóstico,
Registros Médicos,
Estudios Retrospectivos,
Uveítis/tratamiento farmacológico,
Uveítis/diagnóstico,
Agudeza Visual,
Prueba de Tuberculina,
Antituberculosos/uso terapéutico,
Mycobacterium tuberculosis/efectos de los fármacos,
Prednisona/uso terapéutico,
Técnicas de Diagnóstico Oftalmológico
ABSTRACT Setting: Treatment of tuberculosis (TB) can result in Drug-Induced Liver Injury (DILI) since hepatotoxic metabolites are formed during the biotransformation of isoniazid (INH).DILI can be related to the genetic profile of the patient. Single nucleotide polymorphisms in the CYP2E1 gene and GSTM1...
Antituberculosos/efectos adversos,
Antituberculosos/uso terapéutico,
Enfermedad Hepática Inducida por Sustancias y Drogas/enzimología,
Enfermedad Hepática Inducida por Sustancias y Drogas/genética,
Citocromo P-450 CYP2E1,
Sistema Enzimático del Citocromo P-450/genética,
Familia 2 del Citocromo P450,
Predisposición Genética a la Enfermedad/genética,
Genotipo,
Hígado/efectos de los fármacos,
Hígado/enzimología,
Polimorfismo Genético,
Estudios Prospectivos,
Tuberculosis Pulmonar/tratamiento farmacológico,
Tuberculosis Pulmonar/enzimología
