Menezes-Rodrigues, Francisco Sandro;
Ferraz, Renato Ribeiro Nogueira;
Oliveira, Alex Sandro Felisberto;
Silva, Marcos José da;
Bergantin, Leandro Bueno;
Ambrósio, Ricardo Thiago Paniza;
Fantoni, Alessandra de Oliveira;
Paula, Luciana de;
Errante, Paolo Ruggero;
Serinolli, Mário Ivo;
Caricati-Neto, Afonso.
Introdução: A hipertensão arterial é um dos fatores de risco para doenças cardiovasculares, estando diretamente associada ao elevado consumo de sódio. Objetivo: Avaliar os níveis de marcadores de lesão hepática, renal e cardíaca em
ratos hipertensos comparados aos seus controles normotensos, tr...
Ratas Wistar,
28573,
d0069730,
Biomarcadores,
Suplementos Dietéticos,
Cloruro de Sodio Dietético,
Creatina Quinasa/sangre,
L-Lactato Deshidrogenasa/sangre,
Ácido Úrico/sangre,
Aspartato Aminotransferasas/sangre,
Fosfatasa Alcalina/sangre,
Frecuencia Cardíaca
ABSTRACT BACKGROUND Severe Acute Liver Failure (ALF) is a life-threatening clinical syndrome characterized by hepatocyte necrosis, loss of hepatic architecture, and impairment of liver functions. One of the main causes of ALF is hepatotoxicity from chemical agents, which damage hepatocytes and result in...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Antioxidantes/uso terapéutico,
Aspartato Aminotransferasas/sangre,
Modelos Animales de Enfermedad,
Fallo Hepático Agudo/enzimología,
Fallo Hepático Agudo/patología,
Fallo Hepático Agudo/prevención & control,
Ratas Wistar,
Especies de Nitrógeno Reactivo/metabolismo,
Especies Reactivas de Oxígeno/metabolismo,
Índice de Severidad de la Enfermedad,
Vitamina E/uso terapéutico
ABSTRACT Background and rationale. Many different non-invasive methods have been studied with the purpose of staging liver fibrosis. The objective of this study was verifying if transient elastography is superior to aspartate aminotransferase to platelet ratio index for staging fibrosis in patients with...
Aspartato Aminotransferasas/sangre,
Pruebas Enzimáticas Clínicas/métodos,
Diagnóstico por Imagen de Elasticidad/métodos,
Hepatitis C/sangre,
Hepatitis C/diagnóstico por imagen,
Cirrosis Hepática/sangre,
Cirrosis Hepática/diagnóstico por imagen,
Recuento de Plaquetas,
Área Bajo la Curva,
Biomarcadores/sangre,
Biopsia,
Hepatitis C/virología,
Cirrosis Hepática/virología,
Oportunidad Relativa,
Valor Predictivo de las Pruebas,
Pronóstico,
Curva ROC,
Reproducibilidad de los Resultados,
Índice de Severidad de la Enfermedad
ABSTRACT Objective The objective of this study is to evaluate the performance of mathematical models used in non-invasive diagnosis of liver fibrosis in nonalcoholic fatty liver disease (NAFLD) patients to determine when the patient needs to be referred to a hepatologist. Subjects and methods Patient...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Biopsia,
Progresión de la Enfermedad,
Endocrinólogos,
Gastroenterólogos,
Hígado/patología,
Cirrosis Hepática/patología,
Modelos Teóricos,
Enfermedad del Hígado Graso no Alcohólico/patología,
Estándares de Referencia,
Derivación y Consulta,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad,
Índice de Severidad de la Enfermedad
ABSTRACT Background. In clinical practice, it is assumed that a severe rise in transaminases is caused by ischemic, viral or toxic hepatitis. Nevertheless, cases of biliary obstruction have increasingly been associated with significant hypertransaminemia. With this study, we sought to determine the true...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Cálculos Biliares/sangre,
Biomarcadores/sangre,
Colecistectomía,
Servicio de Urgencia en Hospital,
Cálculos Biliares/diagnóstico,
Cálculos Biliares/etiología,
Cálculos Biliares/cirugía,
Admisión del Paciente,
Valor Predictivo de las Pruebas,
Recurrencia,
Estudios Retrospectivos,
Factores de Riesgo,
Regulación hacia Arriba,
Portugal
Abstract Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively (dissolved in olive oil or in saline soluti...
Antioxidantes/farmacología,
Carotenoides/farmacología,
Hepatectomía/métodos,
Hígado/efectos de los fármacos,
Hígado/cirugía,
Estilbenos/farmacología,
Alanina Transaminasa/sangre,
Apoptosis/efectos de los fármacos,
Aspartato Aminotransferasas/sangre,
Hígado/enzimología,
Hígado/patología,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Estrés Oxidativo/efectos de los fármacos,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
ABSTRACT Primary graft dysfunction is a multifactorial syndrome with great impact on liver transplantation outcomes. This review article was based on studies published between January 1980 and June 2015 and retrieved from PubMed database using the following search terms: “primary graft dysfunction&...
Trasplante de Hígado/efectos adversos,
Disfunción Primaria del Injerto,
Donantes de Tejidos,
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Supervivencia de Injerto,
Disfunción Primaria del Injerto/diagnóstico,
Disfunción Primaria del Injerto/etiología,
Disfunción Primaria del Injerto/fisiopatología,
Factores de Riesgo,
Síndrome
Abstract Background: Clinical studies have demonstrated that adipocytokines play an important role in developing atherosclerotic cardiovascular diseases. Objective: The aim of study was to evaluate the relationship between serum resistin and leptin levels with obesity and coronary artery disease (CAD)....
Análisis de Varianza,
Antropometría,
Aspartato Aminotransferasas/sangre,
Proteína C-Reactiva/análisis,
Estudios de Casos y Controles,
Colesterol/sangre,
Enfermedad de la Arteria Coronaria/sangre,
Creatina Quinasa/sangre,
Estudios Transversales,
L-Lactato Deshidrogenasa/sangre,
Leptina/sangre,
Obesidad/sangre,
Valores de Referencia,
Análisis de Regresión,
Resistina/sangre,
Factores de Riesgo,
Estadísticas no Paramétricas,
Triglicéridos/sangre
ABSTRACT Objective In this study, the effects of a green banana pasta diet on the oxidative damage from type 1 diabetes mellitus (DM) were investigated. Materials and methods Formulations containing 25 (F25), 50 (F50), and 75% (F75) of green banana pasta were prepared and included in a 12-week diet o...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Glucemia/análisis,
Colesterol/sangre,
Creatinina/sangre,
Complicaciones de la Diabetes/metabolismo,
Complicaciones de la Diabetes/prevención & control,
Diabetes Mellitus Experimental/metabolismo,
Diabetes Mellitus Experimental/prevención & control,
Diabetes Mellitus Tipo 1/metabolismo,
Diabetes Mellitus Tipo 1/prevención & control,
Dietoterapia/métodos,
Riñón/metabolismo,
Hígado/metabolismo,
Musa/química,
Valores de Referencia,
Reproducibilidad de los Resultados
We report an asymptomatic 23-year-old woman with an isolated and persistent increase in serum levels of aspartate aminotransferase (AST). An extensive work up including laboratory and image testing revealed no abnormalities thus suggesting the presence of macro-AST. A polyethylene glycol (PEG) precipitat...
