ABSTRACT Objective: Molecular methods have practical difficulties in identifying sub-groups of diffuse large B-cell lymphoma (DLBCL) in routine clinical practice. The goal of this study was to sub-classify DLBCL patients into sub-groups by immunohistochemical method and to evaluate the effects of sub-gr...
The liver as an organ is important for the metabolism of drugs and toxins. However, it is not immune from environmental insults. Exposure of liver cells to carbon tetrachloride (CCl4) results in the generation of tricholoromethyl radicals, which induce liver toxicity. This study a...
Resumen Introducción: Clostridioides difficile causa diarrea y colitis pseudomembranosa. Su diagnóstico se realiza con la detección de glutamato-deshidrogenasa (GDH) o las toxinas A y B y se confirma con pruebas de amplificación de ácidos nucleicos. Objetivo: Definir si la determinación de GDH es...
Proteínas Bacterianas/análisis,
Toxinas Bacterianas/análisis,
Teorema de Bayes,
Biomarcadores/análisis,
Clostridioides difficile,
Infecciones por Clostridium/diagnóstico,
Infecciones por Clostridium/epidemiología,
Diarrea/microbiología,
Enterotoxinas/análisis,
Heces/química,
Heces/enzimología,
Glutamato Deshidrogenasa/análisis,
Funciones de Verosimilitud,
Prevalencia,
Estudios Retrospectivos,
Sensibilidad y Especificidad
Gonçalves, Fabio Augusto Rodrigues;
Besen, Bruno Adler Maccagnan Pinheiro;
Lima, Clarice Antunes de;
Corá, Aline Pivetta;
Pereira, Antônio José Rodrigues;
Perazzio, Sandro Félix;
Gouvea, Christiane Pereira;
Fonseca, Luiz Augusto Marcondes;
Trindade, Evelinda Marramon;
Sumita, Nairo Massakazu;
Duarte, Alberto José da Silva;
Lichtenstein, Arnaldo;
Bonfa, Eloisa;
Utiyama, Edivaldo M.;
Segurado, Aluisio C.;
Perondi, Beatriz;
Miethke-Morais, Anna;
Montal, Amanda C.;
Harima, Leila;
Fusco, Solange R. G.;
Silva, Marjorie F.;
Rocha, Marcelo C.;
Marcilio, Izabel;
Rios, Izabel Cristina;
Kawano, Fabiane Yumi Ogihara;
Jesus, Maria Amélia de;
Kallas, Ésper George;
Carmo, Carolina;
Tanaka, Clarice;
Souza, Heraldo Possolo de;
Marchini, Julio F. M.;
Carvalho, Carlos;
Ferreira, Juliana C.;
Levin, Anna Sara Shafferman;
Oliveira, Maura Salaroli;
Guimarães, Thaís;
Lázari, Carolina dos Santos;
Sabino, Ester;
Magri, Marcello M. C.;
Barros-Filho, Tarcisio E. P.;
Francisco, Maria Cristina Peres Braido;
Costa, Silvia F..
OBJECTIVE: Coronavirus disease 2019 (COVID-19) is associated with high mortality among hospitalized patients and incurs high costs. Severe acute respiratory syndrome coronavirus 2 infection can trigger both inflammatory and thrombotic processes, and these complications can lead to a poorer prognosis. Thi...
Diabetes Mellitus Tipo 2/complicaciones,
Diabetes Mellitus Tipo 2/psicología,
Cognición/fisiología,
Biomarcadores/análisis,
Trastornos del Conocimiento/etiología,
Diabetes Mellitus Tipo 2/terapia,
Control Glucémico,
Conducta de Reducción del Riesgo,
Ejercicio Físico/fisiología,
Trastornos del Conocimiento/prevención & control,
Pérdida de Peso/fisiología,
Factores de Tiempo
Characidium sp. aff. C. vidali is a species found in coastal streams in southeastern Brazil, which has karyotypic explanatory elements as the occurrence of microstructural variations, keeping the chromosomal macrostructure of the genus. The objective of this study was to apply cytomolecular tools in the ...
Bronchoalveolar lavage fluid (BALF) was analyzed to obtain information on leakage of acute-phase proteins from the blood into the respiratory lumen and about local synthesis. Ceruloplasmin, transferrin, albumin, α1-antitripsin, immunoglobulin G heavy, immunoglobulin G light, immunoglobulin A, haptog...
Introducción: Actualmente se buscan biomarcadores que se modifiquen paralelamente con la historia natural de la sepsis. Objetivo: Describir las variaciones de la proteína C reactiva, la eritrosedimentación y el conteo de eosinófilos en pacientes graves portadores de enfermedad infecciosa en difere...
Background: Cell culture (spheroid and 2D monolayer cultures) is an essential tool in drug discovery. Piperlongumine (PLN), a naturally occurring alkaloid present in the long pepper (Piper longum), has been implicated in the regulation of GSTP1 activity. In vitro treatment of cancer cells with PLN increa...
Acetaminophen (also called paracetamol, or APAP) causes acute kidney injury after accidental or intentional ingestion of a toxic dose of the drug. We tested whether the antioxidant and anti-inflammatory agent, quercetin (QUR) given alone can protect against acute nephrotoxicity induced by APAP overdose i...
Lesión Renal Aguda/inducido químicamente,
Acetaminofén/toxicidad,
Quercetina/administración & dosificación,
Quercetina/farmacología,
Modelos Animales de Enfermedad,
Biomarcadores/análisis,
Estrés Oxidativo/efectos de los fármacos,
Riñón/efectos de los fármacos,
Sustancias Protectoras,
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Creatinina,
Inflamación
