Hatakeyama, Daniela Miki;
Tasima, Lídia Jorge;
Bravo-Tobar, Cesar Adolfo;
Serino-Silva, Caroline;
Tashima, Alexandre Keiji;
Rodrigues, Caroline Fabri Bittencourt;
Aguiar, Weslei da Silva;
Galizio, Nathália da Costa;
Lima, Eduardo Oliveira Venancio de;
Kavazoi, Victor Koiti;
Gutierrez-Marín, Juan David;
Farias, Iasmim Baptista de;
SantAnna, Sávio Stefanini;
Grego, Kathleen Fernandes;
Morais-Zani, Karen de;
Tanaka-Azevedo, Anita Mitico.
Variability in snake venoms is a well-studied phenomenon. However, sex-based variation of Bothrops atrox snake venom using siblings is poorly investigated. Bothrops atrox is responsible for the majority of snakebite accidents in the Brazilian Amazon region. Differences in the venom composition of Bothrop...
Neuroblastoma is a pediatric tumor with a mortality rate of 40% in the most aggressive cases. Tumor microenvironment components as immune cells contribute to the tumor progression; thereby, the modulation of immune cells to a pro-inflammatory and antitumoral profile could potentialize the immunotherapy, ...
Bothrops atrox is known to be the pit viper responsible for most snakebites and human fatalities in the Amazon region. It can be found in a wide geographical area including northern South America, the east of Andes and the Amazon basin. Possibly, due to its wide distribution and generalist feeding, intra...
Pucca, Manuela B;
Franco, Michelle V. S;
Medeiros, Jilvando M;
Oliveira, Isadora S;
Ahmadi, Shirin;
Cerni, Felipe A;
Zottich, Umberto;
Bassoli, Bruna K;
Monteiro, Wuelton M;
Laustsen, Andreas H.
Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus is responsible for most snakebite-related deaths and permanent loss of function in human victims in Latin America. Bothrops spp. venom is a complex mixture of different proteins...
Burin, Sandra Mara;
Cacemiro, Maira da Costa;
Cominal, Juçara Gastaldi;
Grandis, Rone Aparecido De;
Machado, Ana Rita Thomazela;
Donaires, Flavia Sacilotto;
Cintra, Adelia Cristina Oliveira;
Ambrosio, Luciana;
Antunes, Lusânia Maria Greggi;
Sampaio, Suely Vilela;
Castro, Fabíola Attié de.
Resistance to apoptosis in chronic myeloid leukemia (CML) is associated with constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. The deregulated expression of apoptosis-related genes and alteration in epigenetic machinery may also contribute to apoptosis resistance in CML. Tyrosine kinase i...
The Brazil's lancehead, Bothrops brazili, is a poorly studied pit viper distributed in lowlands of the equatorial rainforests of southern Colombia, northeastern Peru, eastern Ecuador, southern and southeastern Venezuela, Guyana, Suriname, French Guiana, Brazil, and northern Bolivia. Few studies have been...
Introducción. El ofidismo es un relevante problema de salud pública y, en Colombia, se incluyó como un evento de notificación obligatoria desde el año 2004. Por ser un país tropical con gran diversidad ecosistémica, ocupa el tercer puesto en Latinoamérica, después de México y Brasil, en present...
The pitviper Bothrops atrox is a widely distributed and medically important snake in Amazonia. Given that the reproductive and feeding biology of snakes varies geographically, we aimed to characterize the natural history of individuals from the central and southwestern portions of the biome. We analyzed ...
Este estudo objetiva reportar a ocorrência de apoptose in vivo induzida pelo veneno da serpente Bothrops alternatus em células musculares esqueléticas. Cinco coelhos machos, adultos, receberam 150μg/kg de veneno no músculo vasto lateral, enquanto outros cinco animais receberam 0,1% de BSA diluído e...
Abstract Snakebites were included by the World Health Organization in their list of neglected diseases. In Latin America, most snakebites are caused by species of the Viperidae family, notably by the genus Bothrops. Bothrops atrox accounts for 90% of the cases of envenoming in the Brazilian Amazon. In th...
