Results: 56

Correlações entre características da doença hepática gordurosa não-alcoólica e os níveis de adipocinas e citocinas inflamatórias em indivíduos submetidos à cirurgia bariátrica

Arq. gastroenterol; 55 (3), 2018
ABSTRACT BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is the commonest hepatopathy worldwide. OBJECTIVE: To investigate the correlations between NAFLD histopathological features and the levels of adipokines (adiponectin, leptin, and resistin) and circulating inflammatory markers (interleukin-...

Adsorción extracorpórea de citoquinas en el tratamiento del shock séptico refractario: casos clínicos

Rev. méd. Chile; 146 (6), 2018
If Septic shock (SS) evolves to refractory SS, mortality could reach 90%, despite giving an optimal treatment. Nowadays, extracorporeal devices which adsorb inflammatory cytokines are available, reducing the systemic inflammatory response syndrome. These devices can be used with continuous renal replacem...

Protein from Hevea brasiliensis "Hev b 13" latex attenuates systemic inflammatory response and lung lesions in rats with sepsis

Braz. j. biol; 78 (2), 2018
Abstract Sepsis induces a severe systemic inflammatory response that may result in multiple organ dysfunction and death. Studies using a protein derived from natural Hevea brasiliensis (rubber tree) latex, denominated Hev b 13, have demonstrated important anti-inflammatory effects, but no data have been ...

Decreased muscle strength is associated with proinflammatory cytokines but not testosterone levels in men with diabetes

Braz. j. med. biol. res; 51 (9), 2018
The aim of this study was to compare muscle strength in male subjects with type 2 diabetes mellitus (DM2) with and without low plasma testosterone levels and assess the relationship between muscle strength, testosterone levels, and proinflammatory cytokines. Males (75) aged between 18 and 65 years were d...

Interleukin-12 as a biomarker of the beneficial effects of food restriction in mice receiving high fat diet or high carbohydrate diet

Braz. j. med. biol. res; 51 (12), 2018
The impact of food restriction (FR) during 56 days on serum levels of cytokines in mice fed a high-fat diet (HFD) or high-carbohydrate diet (HCD) were evaluated. The amount of food was reduced 50% for HFD-FR and HCD-FR groups compared to mice receiving free access to HFD (HFD group) or HCD (HCD group). W...

Short-term effects of stored homologous red blood cell transfusion on cardiorespiratory function and inflammation: an experimental study in a hypovolemia model

Braz. j. med. biol. res; 51 (1), 2018
The pathophysiological mechanisms associated with the effects of red blood cell (RBC) transfusion on cardiopulmonary function and inflammation are unclear. We developed an experimental model of homologous 14-days stored RBC transfusion in hypovolemic swine to evaluate the short-term effects of transfusio...

[RETRACTED ARTICLE] Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis

Braz. j. med. biol. res; 51 (2), 2018
Caspase recruitment domain-containing protein 9 (Card9) is located upstream of the nuclear factor kappa B (NF-κB) and p38 mitogen-activated protein kinase (MAPK) inflammatory pathways. This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pa...

Circulation levels of acute phase proteins pentraxin 3 and serum amyloid A in atherosclerosis have correlations with periodontal inflamed surface area

J. appl. oral sci; 26 (), 2018
Abstract Objectives One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. This study aims to test the hypothesis that periodontal inflamed surf...

Estudo do perfil de citocinas inflamatórias das doenças desmielinizantes adquiridas na faixa etária pediátrica em ambulatório especializado no estado do Rio de Janeiro
Study of the inflammatory cytokine profile of acquired demyelinating diseases in the pediatric age group in a specialized outpatient clinic in the state of Rio de Janeiro

O grupo de Doenças Desmielinizantes Adquiridas (DDA) acomete o Sistema Nervoso Central (SNC) com base imunopatológica com produção de anticorpos à bainha de mielina. O diagnóstico é baseado em critérios clínico-radiológicos, sendo importante a busca por novas tecnologias para melhores diagnóst...

Circulating omentin-1 might be associated with metabolic health status in different phenotypes of body size

ABSTRACT Objective Adipokines are mediators of body composition and are involved in obesity complications. This study aimed to assess the association of circulating omentin-1, vaspin, and RBP-4 with body composition indices and metabolic health status (MHS) in different phenotypes of body size. Subjec...