Results: 58

Synergistic antibacterial effect of statins with the complex {[1-(4-bromophenyl)-3-phenyltriazene N 3 -oxide-κ 2 N 1,O 4 ](dimethylbenzylamine-κ 2 C 1, N 4 )palladium(II)}

Abstract The treatment of infections caused by resistant microorganisms represents a big challenge in healthcare due to limited treatment options. For this reason, the discovery of new active substances which are able to perform innovative and selective actions is of great impact nowadays. Statins and tr...

Assessment of the preparation and administration of oral medications to institutionalized children

Rev. bras. enferm; 71 (supl.3), 2018
ABSTRACT Objective: to evaluate the preparation and administration of oral medications to institutionalized children by nursing professionals. Method: quantitative study, developed from August to September 2016, in a shelter in Fortaleza, Ceará. 323 observations of preparation and administration of or...

Errores en las recetas médicas y en la preparación de estas en farmacia de pacientes ambulatorios: El caso del Hospital de Nueva Imperial

Rev. méd. Chile; 145 (1), 2017
Background: Adverse effects of medications are an important cause of morbidity and hospital admissions. Errors in prescription or preparation of medications by pharmacy personnel are a factor that may influence these occurrence of the adverse effects Aim: To assess the frequency and type of errors in pre...

Assistência segura ao paciente no preparo e administração de medicamentos

Rev. gaúch. enferm; 38 (4), 2017
Resumo OBJETIVO Avaliar a conformidade da assistência e a adesão dos profissionais de enfermagem para a administração segura de medicamentos em uma Unidade de Terapia Intensiva de um hospital público de Sergipe, Brasil. MÉTODO Estudo quantitativo, descritivo e de corte transversal realizado por m...

Fotoprotetores bioativos multifuncionais contendo rutina, octil dimetil PABA e avobenzona: caracterização físico-química, funcional e eficácia clínica

A exposição crônica à radiação solar pode contribuir para o aparecimento do câncer de pele, sendo o uso de fotoprotetores um fator primordial na prevenção desses efeitos deletérios. Atualmente, substâncias bioativas tais como a rutina têm sido foco de interesse da comunidade científica graç...

Synbiotic aerated dessert: diet product development and evaluation of the intake effects in individuals with metabolic syndrome

The objective of this work was to adapt a synbiotic aerated diet dessert, produced with the addition of a probiotic culture of Lactobacillus acidophilus La-5 and prebiotic ingredients (fructooligosaccharides and inulin), from the previously developed sucrose-containing formulation, and to evaluate the ef...

Liposomes as potential carriers for ketorolac ophthalmic delivery: formulation and stability issues
Liposomes as potential carriers for ketorolac ophthalmic delivery: formulation and stability issues

ABSTRACT Drug delivery to treat ocular disorders locally is a challenging endeavor. Traditional ocular dosage form - eye drops - exhibits poor availability, consequently inefficient therapeutic response. The objective of the study was to formulate and characterize a ketorolac tromethamine ocular system w...

Development and validation of an analytical method using High Performance Liquid Chromatography (HPLC) to determine ethyl butylacetylaminopropionate in topical repellent formulations

ABSTRACT Diseases caused by insects are frequent in poor countries, leading to epidemic scenarios in urban areas; e.g., Dengue, Zika and Chikungunya. For this reason, the development of a safe and efficient topical formulation is essential. Ethyl butylacetylaminopropionate (EB) is a mosquito repellent d...

Evaluation of polymeric PLGA nanoparticles conjugated to curcumin for use in aPDT

ABSTRACT Antimicrobial photodynamic therapy (aPDT) involves the association of a photosensitizing agent with a light source with the goal of causing apoptosis or microbial lysing. The use of compounds with natural active principles is gaining prominence throughout the world. Several studies from groups t...

Optimization of self-nanoemulsifying formulations for weakly basic lipophilic drugs: role of acidification and experimental design

Braz. j. pharm. sci; 52 (4), 2016
ABSTRACT Formulators face great challenges in adopting systematic approaches for designing self-nanoemulsifying formulations (SNEFs) for different drug categories. In this study, we aimed to build-up an advanced SNEF development framework for weakly basic lipophilic drugs, such as cinnarizine (CN). First...