Abstract Hedera nepalensis (H. nepalensis) , belonging to the family Araliaceae, is a medicinal plant traditionally used to treat stomach problems. The current study investigated the gastroprotective potential and the mechanism of action of H. nepalensis in diclofenac-and ethanol-induced ulcer models. An...
Araliaceae/clasificación,
Plantas Medicinales,
Antioxidantes,
Diclofenaco/agonistas,
Úlcera/inducido químicamente,
Úlcera Gástrica/patología,
ddcs0515740,
Cromatografía Líquida de Alta Presión/métodos,
Espectroscopía Infrarroja por Transformada de Fourier/métodos,
Estómago/anomalías,
Hedera/clasificación
Abstract The locust bean gum (LBG) is a polysaccharide with thickening, stabilizing and gelling properties and it has been used in the preparation of pharmaceutical formulations. Hydrogels (HGs) are obtained from natural or synthetic materials that present interesting properties for skin application. Thi...
Abstract The present study entails the systematic development and validation of a stability-indicating RP-HPLC method for the analysis of sitagliptin and ertugliflozin in a fixed-dose combination. Analytical quality by design (AQbD) concepts were used to define critical method variables, employing Pareto...
Abstract Infusion solutions must be stable from the production stage until the infusion stage. Some infusion fluids contain degradation products, known as advanced glycation end products (AGEs); however, it is unknown whether AGEs exist in parenteral nutrition solutions. We aimed to investigate this ques...
Abstract Guarana (Paullinia cupana) is a native plant from the Amazon whose seeds contain a high concentration of caffeine. Aqueous extract of guarana is widely used in the world. In this study, the objective was to develop and validate a High-Performance Liquid Chromatography method for the determinatio...
Abstract Treatment with plant is considered an effective option against increased antibiotic resistance. In this study antibiofilm activity of methanol (CH3OH), chloroform (CHCl3), ethyl acetate (EtOAc) and water (H2O) extracts of Hypericum atomarium Boiss. which is member of Hypericum genus was evaluate...
Abstract Bauhinia forficata Link aqueous extract is usually recommended as a phytomedicine to reduce blood glucose levels and its biological activity has been linked to the presence of phenolic compounds from B. forficata preparations. Several drying processes are used in the production of dry herbal ext...
Abstract The present study investigated the effects of valerian methanolic extract and valerenic acid on the expression of LL-37 gene and protein in A549 and MRC5 line cells. After preparing Valerian seeds, sowing them in March 2020, and harvesting the rhizome in October 2020, the extract was prepared fr...
Valeriana/efectos adversos,
Extractos Vegetales/efectos adversos,
Catelicidinas/efectos adversos,
Genes/genética,
Cromatografía Líquida de Alta Presión/métodos,
ddcs0244440,
Células A549/clasificación,
Hígado/anomalías,
Péptidos Catiónicos Antimicrobianos/agonistas,
d0024700,
Western Blotting/instrumentación
Abstract Betamethasone (BET) is a synthetic glucocorticoid recommended for pregnant women at imminent risk of preterm birth before 34 weeks to reduce neonatal complications. There are different techniques to describe BET plasma quantification. However, none quantified the plasmatic concentration of BET ...
Objective: to investigate the effect of two natural cross-linkers on microtensile bond strength (μTBS) and evaluate their influence on the durability of the resin dentin bonds. Material and Methods: the Moringa oleifera and Centella asiatica plant extracts were qualitatively tested with high-performance...
Reactivos de Enlaces Cruzados/análisis,
Resinas Compuestas/análisis,
Recubrimientos Dentinarios/análisis,
Moringa oleifera/química,
Centella/química,
Extractos Vegetales/química,
Cromatografía Líquida de Alta Presión,
Traumatismos de los Dientes,
Polifenoles/química,
Colágenos Fibrilares/metabolismo,
Flavonoides/química