Background: A simple and efficient strategy for agarase immobilization was developed with carboxyl-functionalized magnetic nanoparticles (CMNPs) as support. The CMNPs and immobilized agarase (agarase-CMNPs) were characterized by transmission electron microscopy, dynamic light scattering, vibrating sample...
Glicósido Hidrolasas/metabolismo,
Enzimas Inmovilizadas,
Nanopartículas de Magnetita/química,
Dispersión Dinámica de Luz,
Termogravimetría,
Microscopía Electrónica de Transmisión,
Magnetometría,
Difracción de Rayos X,
Estabilidad de Enzimas,
Oligosacáridos/metabolismo,
Catálisis,
Glicósido Hidrolasas/química
ABSTRACT Different solid forms of an active pharmaceutical ingredient can have distinct chemical and physical characteristics. In this work, we studied the solubility and dissolution properties of the described tibolone polymorphic forms (I and II). Both forms were successively recrystallized and charact...
Abstract Monolithic restorations of Y-TZP have been recommended as a restorative alternative on prosthetic dentistry as it allows a substantial reduction of ceramic thickness, which means a greater preservation of tooth structure. However, the influence of grinding and aging when using a thinner layer of...
Análisis de Varianza,
Cerámica/química,
Frío,
Ensayo de Materiales,
Microscopía Electrónica de Rastreo,
Docilidad,
Distribución Aleatoria,
Reproducibilidad de los Resultados,
Estadísticas no Paramétricas,
Propiedades de Superficie,
Resistencia a la Tracción,
Factores de Tiempo,
Difracción de Rayos X,
Itrio/química,
Circonio/química
ABSTRACT Objective The corrosion behavior of zirconia in acidulated phosphate fluoride (APF) representing acidic environments and fluoride treatments was studied. Material and Methods Zirconia rods were immersed in 1.23% and 0.123% APF solutions and maintained at 37°C for determined periods of time....
Fluoruro de Fosfato Acidulado/química,
Cerámica/química,
Corrosión,
Implantes Dentales,
Espectroscopía Dieléctrica/métodos,
Inmersión,
Ensayo de Materiales,
Microscopía Electrónica de Rastreo,
Propiedades de Superficie/efectos de los fármacos,
Factores de Tiempo,
Difracción de Rayos X/métodos,
Circonio/química
Background: Microbial-induced remediation of Zn2+ pollution based on the capture and utilization of carbon dioxide was investigated. In this study, carbon dioxide was absorbed and transformed into carbonate ions under the enzymatic action of Paenibacillus mucilaginosus, which was being utilized to minera...
A nistatina (NYS) é o fármaco de primeira escolha no tratamento da candidíase oral, que frequentemente acomete mais os indivíduos imunocomprometidos e pacientes com outras desordens (diabetes não tratada, neoplasias, imunodeficiências). No mercado brasileiro, a NYS é encontrada na forma de suspens...
Abstract The aim of this study is to evaluate the biocompatibility and osteoconductivity in surgical defects of sheep tibias filled with 1% strontium-containing nanostructured hydroxyapatite microspheres (SrHA), stoichiometric hydroxyapatite without strontium microspheres (HA), or blood clots. Santa Ines...
Regeneración Ósea/efectos de los fármacos,
Sustitutos de Huesos/farmacología,
Hidroxiapatitas/farmacología,
Ensayo de Materiales,
Microscopía Electrónica de Rastreo,
Modelos Animales,
Nanoestructuras/química,
Reproducibilidad de los Resultados,
Ovinos,
Espectroscopía Infrarroja por Transformada de Fourier,
Estroncio/farmacología,
Tibia/efectos de los fármacos,
Factores de Tiempo,
Cicatrización de Heridas/efectos de los fármacos,
Difracción de Rayos X,
Microtomografía por Rayos X
abstract Amiodarone HCl is an antiarrhythmic agent, which has low aqueous solubility and presents absorption problems. This study aimed to develop inclusion complexes containing hydrophilic carriers PEG 1500, 4000 and 6000 by fusion and kneading methods in order to evaluate the increase in solubility and...
Introducción: el clopidogrel bisulfato existe en numerosas formas cristalinas, que varían en su estabilidad fisicoquímica, por lo que algunas de estas formas, patentadas o no, son útiles en la fabricación de medicamentos. Objetivo: identificar las formas cristalinas existentes en dos muestras de clo...
A engenharia de tecidos tem como perspectiva desenvolver opções terapêuticas para quadros clínicos com prognóstico limitado, objetivando substituir ou regenerar os tecidos lesados por meio do uso de biomateriais. A metodologia baseia-se no cultivo de células sobre uma matriz ou scaffold que deve se...
