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Effects of crocin on brain oxidative damage and aversive memory in a 6-OHDA model of Parkinson's disease

Rajaei, Z; Hosseini, M; Alaei, H.
Arq. neuropsiquiatr; 74 (9), 2016
ABSTRACT The purpose of the present study was to investigate the effect of crocin on brain oxidative damage and memory deficits in a 6-hydroxydopamine (6-OHDA) model of Parkinson’s disease. Male Wistar rats were subjected to unilateral injection of 6-OHDA (16 µg) into the medial forebrain bundle a...
Antioxidantes/farmacología, Carotenoides/farmacología, Corteza Cerebral/efectos de los fármacos, Corteza Cerebral/metabolismo, Corteza Cerebral/fisiopatología, Modelos Animales de Enfermedad, Glutatión Peroxidasa/análisis, Glutatión Peroxidasa/efectos de los fármacos, Peroxidación de Lípido/efectos de los fármacos, Memoria/efectos de los fármacos, Memoria/fisiología, Trastornos de la Memoria/metabolismo, Trastornos de la Memoria/fisiopatología, Trastornos de la Memoria/prevención & control, Nitritos/análisis, Estrés Oxidativo/efectos de los fármacos, Oxidopamina, Enfermedad de Parkinson/tratamiento farmacológico, Enfermedad de Parkinson/metabolismo, Enfermedad de Parkinson/fisiopatología, Distribución Aleatoria, Ratas Wistar, Compuestos de Sulfhidrilo/análisis, Sustancias Reactivas al Ácido Tiobarbitúrico/análisis
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Postural instability and falls are more frequent in Parkinson's disease patients with worse trunk mobility

Artigas, Nathalie Ribeiro; Franco, Clarissa; Leão, Paula; Rieder, Carlos R M.
Arq. neuropsiquiatr; 74 (7), 2016
ABSTRACT Postural instability and axial rigidity are frequent symptoms of the Parkinson’s disease (PD). Objective Correlate the occurrence of falls and the activity of rolling over in bed with performance on the Trunk Mobility Scale (TMS) in patients with PD, and determine whether this instrument...
Accidentes por Caídas/prevención & control, Accidentes por Caídas/estadística & datos numéricos, Actividades Cotidianas, Lechos, Estudios Transversales, Limitación de la Movilidad, Movimiento/fisiología, Enfermedad de Parkinson/complicaciones, Enfermedad de Parkinson/fisiopatología, Equilibrio Postural/fisiología, Reproducibilidad de los Resultados, Medición de Riesgo/métodos, Factores de Riesgo, Sensibilidad y Especificidad, Índice de Severidad de la Enfermedad, Torso/fisiopatología
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Speech disorders did not correlate with age at onset of Parkinson's disease

Dias, Alice Estevo; Barbosa, Maira Tonidandel; Limongi, João Carlos Papaterra; Barbosa, Egberto Reis.
Arq. neuropsiquiatr; 74 (2), 2016
ABSTRACT Speech disorders are common manifestations of Parkinson´s disease. Objective To compare speech articulation in patients according to age at onset of the disease. Methods Fifty patients was divided into two groups: Group I consisted of 30 patients with age at onset between 40 and 55 years; Group...
Edad de Inicio, Enfermedad de Parkinson/complicaciones, Enfermedad de Parkinson/fisiopatología, Índice de Severidad de la Enfermedad, Trastornos del Habla/etiología, Trastornos del Habla/fisiopatología
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Main determinants of physical activity levels in individuals with Parkinson's disease

Lana, Raquel de Carvalho; Araujo, Lysandra Nogueira de; Cardoso, Francisco; Rodrigues-de-Paula, Fátima.
Arq. neuropsiquiatr; 74 (2), 2016
ABSTRACT This study analyzed the relationship between patient characteristics, factors associated with Parkinson’s disease (PD), and physical activity level of individuals affected by the disease. Forty-six volunteers with mild-to-moderate idiopathic PD were assessed using sections II/III of the Un...
Actividades Cotidianas, Estudios Transversales, Evaluación de la Discapacidad, Ejercicio Físico, Fatiga/fisiopatología, Actividad Motora/fisiología, Pruebas Neuropsicológicas, Enfermedad de Parkinson/fisiopatología, Calidad de Vida, Índice de Severidad de la Enfermedad
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Validation and reliability of a modified sphygmomanometer for the assessment of handgrip strength in Parkinson´s disease

Silva, Soraia M; Corrêa, Fernanda I; Silva, Paula F. C; Silva, Daniela F. T; Lucareli, Paulo R. G; Corrêa, João C. F.
Braz. j. phys. ther. (Impr.); 19 (2), 2015
BACKGROUND: Handgrip strength is currently considered a predictor of overall muscle strength and functional capacity. Therefore, it is important to find reliable and affordable instruments for this analysis, such as the modified sphygmomanometer test (MST). OBJECTIVES: To assess the concurrent criterion ...
Fuerza de la Mano, Enfermedad de Parkinson/fisiopatología, Esfigmomanometros, Diseño de Equipo, Reproducibilidad de los Resultados
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Postural control in Parkinson's disease

Fukunaga, Jackeline Yumi; Quitschal, Rafaela Maia; Doná, Flávia; Ferraz, Henrique Ballalai; Ganança, Maurício Malavasi; Caovilla, Heloísa Helena.
Braz. j. otorhinolaryngol. (Impr.); 80 (6), 2014
Introduction: Postural instability is one of the most disabling features of Parkinson's disease. Objective: To evaluate postural balance in Parkinson's disease. Methods: Thirty patients with Parkinson's disease were compared with controls using Tetrax™ interactive balance system posturography. Resu...
Estudios de Casos y Controles, Análisis de Fourier, Enfermedad de Parkinson/fisiopatología, Equilibrio Postural/fisiología, Trastornos de la Sensación/fisiopatología, Índice de Severidad de la Enfermedad
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Restrição visual e oscilações corporais ântero-posteriores na doença de Parkinson

Sánchez-Arias, Mônica Del Rosario; Kleiner, Ana Francisca Rozin; Hamanaka, Ágata Yoko Yasue; Santiago, Paulo Roberto Pereira; Gobbi, Lilian Teresa Bucken; Stella , Florindo.
Acta fisiátrica; 19 (3), 2012
Sem visão poucos ajustes antecipatórios e/ou compensatórios ocorrem na doença de Parkinson e as evidências destes ajustes são menores quando a evolução da doença e as oscilações corporais são consideradas. Objetivo: O objetivo deste estudo foi evidenciar os efeitos da restrição visual sobre...
Enfermedad de Parkinson/fisiopatología, Trastorno de Movimiento Estereotipado, Trastornos de la Visión, Postura
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