Introdução: a epilepsia é uma doença neurológica, cuja prevalência é de 0,5 a 1% na população, sendo que 20 a 30% dos pacientes apresentam crises refratárias ao tratamento medicamentoso. A dieta cetogênica (DC) composta por alto teor de gorduras, baixo teor de carboidratos e quantidade proteic...
ABSTRACT The purpose of this work was to evaluate the influence of the clinical profile on lamotrigine (LTG) plasma concentrations from patients with refractory epileptic seizures. In this cross-sectional study, therapeutic monitoring of LTG, and questionnaires with 75 patients with refractory epileptic ...
ABSTRACT Vagus nerve stimulation is an adjunctive therapy used to treat patients with refractory epilepsy who are not candidates for resective surgery or had poor results after surgical procedures. Its mechanism of action is not yet fully comprehended but it possibly involves modulation of the locus coer...
ABSTRACT The ketogenic diet (KD) is a nonpharmacologic treatment that has been used for refractory epilepsy since 1921. The KD is a high-fat, low-carbohydrate, and restricted protein diet, which is calculated and weighed for each individual patient. Introducing and maintaining the diet for a long time re...
INTRODUCCIÓN: Antecedentes: El presente informe está referido a la evaluación de la eficacia y seguridad del dispositivo médico Estimulador del Nervio Vago (ENV) en pacientes con el diagnóstico de Epilepsia Resistente a Fármacos, solicitado por el Hospital Edgardo Rebagliati Martins. Aspectos Gener...
La epilepsia del lóbulo temporal es la forma más frecuente de epilepsia focal refractaria a tratamiento médico. Se estima que hasta 70% de los pacientes con epilepsia del lóbulo temporal tienen una alteración morfológica del hipocampo, la esclerosis temporal mesial, que se caracteriza por pérdida ...
ABSTRACT Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in people with intractable epilepsy. Probably, optimization of seizure control will prevent some of these deaths. Briefly, we integrated in this paper some data about the epidemiology, risk factors, etiology, and preve...
INTRODUCCIÓN: Antecedentes: El presente dictamen expone la evaluación de tecnología del uso del radiotrazador de medicina nuclear F-18 FDG para la búsqueda de foco epileptógeno en Tomografías de Emisión de Positrones (PET) en pacientes con epilepsia refractaria y posibles candidatos a cirugía. As...