Abstract: Background: Recent studies that investigated the effect of vitamin D on skin cancer risk have exhibited inconsistent results. Objective: The aim of the study was to evaluate vitamin D status in patients with actinic keratosis. Methods: A cross-sectional study was conducted on 31 patients wit...
Aflatoxin B1 is a carcinogenic and mutagenic mycotoxin produced mainly by Aspergillus flavus and Aspergillus parasiticus. It is the predominant mycotoxin found in raw materials used for the manufacture of broiler feeds. The aim of the present study was to develop a new and optimized method for the detect...
Resumo: Introdução: A classe de drogas de abuso conhecida como novas substâncias psicoativas ou, ainda, drogas desenhadas (do inglês new psychoactive substances (NPS) ou designer drugs) é composta por substâncias químicas obtidas a partir de alterações estruturais de substâncias ou mistura de s...
As bifenilas policloradas (PCBs) são um grupo de compostos hidrocarbonetos halogenados aromáticos, bioacumulativos em organismos vivos e persistente no ambiente. Além da atividade disruptora endócrina, os PCBs podem aumentar os níveis de espécies reativas de oxigênio (ROS), levando ao estresse oxi...
ABSTRACT A simple, sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the quantification of cabozantinib (CZ) in human plasma using cabozantinib-d4 (CZD4) as an internal standard (IS). Chromatographic separation was performed on Xbridge C18, 50 x 4.6...
El-Aziz, Tarek Mohamed Abd;
Khoury, Sawsan Al;
Jaquillard, Lucie;
Triquigneaux, Mathilde;
Martinez, Guillaume;
Bourgoin-Voillard, Sandrine;
Sève, Michel;
Arnoult, Christophe;
Beroud, Rémy;
Waard, Michel De.
Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, ...
Abstract Saliva contains numerous proteins and peptides, each of them carries a number of biological functions that are very important in maintaining the oral cavity health and also yields information about both local and systemic diseases. Currently, proteomic analysis is the basis for large-scale ident...
ABSTRACT Purpose: To compare the aqueous humor (AH) concentrations of moxifloxacin 0.5% and gatifloxacin 0.3% solutions alone or when treatment was combined with steroids, and to correlate these concentrations with the minimum inhibitory concentrations (MIC) for the most common endophthalmitis-causing o...
Antibacterianos/análisis,
Antibacterianos/farmacología,
Humor Acuoso/química,
Cromatografía Líquida de Alta Presión,
Enterococcus/efectos de los fármacos,
Enterococcus/aislamiento & purificación,
Fluoroquinolonas/análisis,
Fluoroquinolonas/farmacología,
Gatifloxacina,
Pruebas de Sensibilidad Microbiana,
Moxifloxacino,
Esteroides/análisis,
Valores de Referencia,
Staphylococcus aureus/efectos de los fármacos,
Espectrometría de Masas en Tándem,
Streptococcus pneumoniae/aislamiento & purificación
Céspedes, Nora;
Valencia, Angela;
Echeverry, Carlos Alberto;
Arce-Plata, Maria Isabel;
Colón, Cristóbal;
Castiñeiras, Daisy E;
Hurtado, Paula Margarita;
Cocho, Jose Angel;
Herrera, Sócrates;
Arévalo-Herrera, Myriam.
Abstract Introduction: Inborn errors of metabolism (IEM) represent an important public health problem due to current diagnosis and treatment limitations, poor life quality of affected patients, and consequent untimely child death. In contrast to classical methods, tandem mass spectrometry (MS/MS) has al...
Aminoácidos/Sangre,
Carnitina/análogos & derivados,
Heptanoatos/Sangre,
Errores Innatos del Metabolismo/diagnóstico,
Espectrometría de Masas en Tándem/Métodos,
Biomarcadores/Sangre,
Carnitina/Sangre,
Colombia,
Estudios Transversales,
Reacciones Falso Positivas,
Errores Innatos del Metabolismo/Sangre,
Valores de Referencia,
Sensibilidad y Especificidad
Abstract: Objective: Inborn errors of metabolism (IEM) are genetic conditions that are sometimes associated with intellectual developmental disorders (IDD). The aim of this study is to contribute to the metabolic characterization of IDD of unknown etiology in Mexico. Materials and methods: Metabolic ...
