ABSTRACT Extraction of effective components from Pueraria lobata has important value for skeletal muscle quality and gene expression. The improvement effect of traditional high-intensity intermittent training on skeletal muscle has not been obvious, and it is difficult to guarantee the properties of some...
BACKGROUND: Molecular brain therapies require the development of molecular switches to control gene expression in a limited and regulated manner in time and space. Light-switchable gene systems allow precise control of gene expression with an enhanced spatio-temporal resolution compared to chemical induc...
Abstract Hydrosalpinx is a disease characterized by the obstruction of the salpinx, with progressive accumulation in the shape of a fluid-filled sac at the distal part of the tuba uterina, and closed to the ovary. Women with hydrosalpinges have lower implantation and pregnancy rates due to a combination ...
Blastocisto/fisiología,
Implantación del Embrión,
Endometrio/fisiopatología,
Enfermedades de las Trompas Uterinas/complicaciones,
Enfermedades de las Trompas Uterinas/fisiopatología,
Enfermedades de las Trompas Uterinas/cirugía,
Fertilización In Vitro,
Expresión Génica,
Proteínas Homeobox A10/genética,
Infertilidad Femenina/etiología,
Infertilidad Femenina/terapia,
Salpingectomía,
Insuficiencia del Tratamiento
Resumen Introducción: El linfoma de Hodgkin clásico presenta escasas células de Reed Sternberg/Hodgkin inmersas en un abundante microambiente tumoral. Los desbalances genómicos del locus 9p24.1 han sido asociados con alteraciones en la expresión de los genes del ligando de muerte celular 1 y 2, amb...
Bovine clinical mastitis caused by Staphylococcus spp. is a serious and widespread disease in the world of dairy farming. Antimicrobial therapy is of fundamental importance in the prevention and treatment of infectious mastitis, but the indiscriminate use of antimicrobials acts as a determining factor fo...
Zhao, Lina;
Yang, Xi;
Feng, Chun;
Wang, Yue;
Wang, Qing;
Pei, Jiahong;
Wu, Jinting;
Li, Shuaiying;
Zhang, Honglei;
Cao, Xianbao.
BACKGROUND: Cross talk of tumor–immune cells at the gene expression level has been an area of intense research. However, it is largely unknown at the alternative splicing level which has been found to play important roles in the tumor–immune microenvironment. RESULTS: Here, we re-exploited one transc...
Hajrah, Nahid H;
Rabah, Samar O;
Alghamdi, Mohammed K;
Atef, Ahmed;
Edris, Sherif;
Alhebshi, Alawiah M;
Hassan, Sabah M;
Alzahrani, Dhafer A;
Bahieldin, Ahmed;
Mutwakil, Mohammed HZ;
Alqurashi, Yaser E;
Al-Zahrani, Hassan S;
Abo-Aba, Salah EM;
Jansen, Robert K;
Sabir, Jamal SM;
Hall, Neil;
Rasool Kamli, Majid.
BACKGROUND: Jasmonic acid (JA) is a signal transducer molecule that plays an important role in plant development and stress response; it can also efficiently stimulate secondary metabolism in plant cells. RESULTS: RNA-Seq technology was applied to identify differentially expressed genes and study the tim...
El término CRISPR, por su acrónimo en inglés refiere a Clustered Regularly Interspaced Short Palindromic Repeats, es decir, repeticiones palindrómicas cortas, agrupadas y regularmente esparcidas, por sus características en el genoma, pertenece naturalmente al sistema de defensa de bacterias y arquea...
Biotecnología,
Enfermedades Genéticas Congénitas/terapia,
Epigenómica/tendencias,
Expresión Génica,
Genoma Humano/genética,
Neoplasias/terapia,
Proteínas Asociadas a CRISPR/genética,
Proteínas Asociadas a CRISPR/uso terapéutico,
Regulación de la Expresión Génica,
Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas/genética,
Sistemas CRISPR-Cas/genética,
Terapia Genética/métodos
Mutações somáticas não sinônimas podem iniciar a tumorigênese e, também, uma resposta citotóxica antitumoral. Com o desenvolvimento das tecnologias de sequenciamento, tornou-se possível identificar as mutações em todos os genes humanos e, consequentemente, as variantes que induzem uma resposta...
Leishmania infantum chagasi is the causative agent and Lutzomyia longipalpis is the main vector of visceral leishmaniasis in the Americas. We investigated the expression of Leishmania genes within L. longipalpis after artificial infection. mRNAs from genes involved in sugar and amino acid metabolism were...
Brasil,
Expresión Génica,
Insectos Vectores/parasitología,
Leishmania/aislamiento & purificación,
Leishmania infantum/genética,
Leishmaniasis Visceral/epidemiología,
Leishmaniasis Visceral/parasitología,
Leishmaniasis Visceral/transmisión,
Estadios del Ciclo de Vida,
Psychodidae/genética,
Psychodidae/parasitología,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa/métodos
