Abstract Purpose: To evaluate liver regeneration after selective ligation of portal vein and hepatic artery by 3D Computed Tomography in an experimental model. Methods: Sixteen Wistar rats were randomized into four equal groups: Group I- control (sham), Group II- isolated selective ligation of the hepa...
Arteria Hepática/cirugía,
Hepatomegalia/diagnóstico por imagen,
Hepatomegalia/fisiopatología,
Imagenología Tridimensional/métodos,
Inmunohistoquímica,
Ligadura,
Hígado/irrigación sanguínea,
Hígado/diagnóstico por imagen,
Hígado/patología,
Regeneración Hepática/fisiología,
Tamaño de los Órganos/fisiología,
Vena Porta/cirugía,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Tomografía Computarizada por Rayos X/métodos,
Resultado del Tratamiento
The objective of the present study was to characterize the biochemical, hormonal, and mineral profile, and histopathology of the liver and kidneys, related to the severity of natural cases of pregnancy toxemia (PT) in sheep. A total of 45 sheep with PT were analyzed at the "Clínica de Bovinos", Campus G...
Trevisan, Alexandre Maximiliano;
Cogliati, Bruno;
Homem, Adriana Ribeiro;
Aloiav, Thiago Pinheiro Arrais;
Aquino Neto, Nelson de;
Moreira, Jairo Marques;
Reno, Leonardo da Cruz;
Naumann, Alexandre Moulin;
Galvão, Flavio Henrique Ferreira;
Andraus, Wellington;
D'Albuquerque, Luiz Augusto Carneiro.
Abstract Purpose: To evaluate that Connexin (Cx43) plays a role in lesions after hepatic ischemia/reperfusion (IR) injury. Methods: We use Cx43 deficient model (heterozygotes mice) and compared to a wild group. The groups underwent 1 hour ischemia and 24 hours reperfusion. The heterozygote genotype was...
Alanina Transaminasa/análisis,
Aspartato Aminotransferasas/análisis,
Conexina 43/análisis,
Conexina 43/deficiencia,
Modelos Animales de Enfermedad,
Técnicas de Genotipaje,
Hígado/irrigación sanguínea,
Hígado/patología,
Ratones Noqueados,
Necrosis,
Reacción en Cadena de la Polimerasa,
Valores de Referencia,
Daño por Reperfusión/metabolismo,
Daño por Reperfusión/patología,
Factores de Tiempo,
gamma-Glutamiltransferasa/análisis
ABSTRACT BACKGROUND: Non-alcoholic fatty liver disease has been progressively diagnosed in the general population as a consequence of the increased prevalence of obesity and type 2 diabetes mellitus, its main risk factors. It is characterized by accumulation of fat in the hepatocytes associated with lo...
Biopsia,
Progresión de la Enfermedad,
Diagnóstico por Imagen de Elasticidad,
Estudios de Seguimiento,
Hígado/patología,
Cirrosis Hepática/diagnóstico por imagen,
Cirrosis Hepática/patología,
Persona de Mediana Edad,
Enfermedad del Hígado Graso no Alcohólico/diagnóstico por imagen,
Enfermedad del Hígado Graso no Alcohólico/patología,
Factores de Riesgo
Abstract Objective: To describe the demographic, clinical, laboratory and molecular characteristics of patients with lysosomal acid lipase deficiency. Methods: A retrospective review of the medical records of children with the disease. Results: Seven children with lysosomal acid lipase deficiency (5 m...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biopsia,
Brasil,
Colesterol/sangre,
Dislipidemias/patología,
Hepatomegalia/patología,
Hígado/patología,
Registros Médicos,
Estudios Retrospectivos,
Triglicéridos/sangre,
Enfermedad de Wolman/patología
La fiebre Q aguda es una zoonosis ubicua, que habitualmente se presenta con cuadros febriles autolimitados. En presencia de un cuadro séptico con manifestaciones de disfunción multiórgano, hepatitis colestásica, distres respiratorio o la insuficiencia renal como semiología dominante y cultivos negat...
Porta, Gilda;
Carvalho, Elisa de;
Santos, Jorge L;
Gama, Jorge;
Borges, Cristian V;
Seixas, Renata B P M;
Ferreira, Alexandre R;
Miura, Irene K;
Silveira, Themis R;
Silva, Luciana R;
Fagundes, Eleonora D T;
Bellomo-Brandao, Maria A;
Sawamura, Regina;
Vieira, Sandra M;
Melere, Melina U;
Marques, Cibele D F;
Pugliese, Renata P;
Danesi, Vera L;
Porta, Adriana;
Marsillac, Marise E;
Valladares, Marcia A;
Menezes, Daniela G;
Kieling, Carlos;
Paula, Mariana N de;
Vasconcelos, Juliana R;
Ferreira, Cristina T;
Perin, Nilza;
Resende, Leonardo R;
Maia, Jussara;
Tommaso, Adriana M A De;
Hessel, Gabriel.
Abstract Objective: This large study with a long-term follow-up aimed to evaluate the clinical presentation, laboratory findings, histological profile, treatments, and outcomes of children and adolescents with autoimmune hepatitis. Methods: The medical records of 828 children and adolescents with autoi...
Anticuerpos Antinucleares/sangre,
Autoanticuerpos/análisis,
Azatioprina/uso terapéutico,
Biopsia con Aguja,
Brasil,
Hepatitis Autoinmune/tratamiento farmacológico,
Hepatitis Autoinmune/inmunología,
Hepatitis Autoinmune/patología,
Inmunoglobulinas/análisis,
Terapia de Inmunosupresión,
Inmunosupresores/uso terapéutico,
Hígado/patología,
Imagen por Resonancia Magnética,
Prednisona/uso terapéutico,
Estudios Retrospectivos,
Análisis de Supervivencia,
Resultado del Tratamiento
Background: A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively. Aim: To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material and Methods: Three algorithms were implemented: region ...
Abstract The catfish, Clarias gariepinus, was exposed to different acute concentrations (5-10 mg/l) of diazinon and the Lc50 value was recorded as high as 7.3 mg/l for 96 hours. The fishes exposed to three sub-lethal levels of diazinon (0.73, 1.095 and 1.46 mg/l) for 30 days showed that the pesticide in...
ABSTRACT BACKGROUND: The bacterium Helicobacter pylori is strongly associated with the development of gastric adenocarcinoma. Currently, the prevalence in developed countries is 40%, but this value increases considerably in developing countries, which can reach rates bigger than 90%. OBJECTIVE: The o...
Biopsia,
Glucemia/análisis,
Índice de Masa Corporal,
HDL-Colesterol/sangre,
Estudios Transversales,
Ferritinas/sangre,
Homeostasis/fisiología,
Insulina/sangre,
Resistencia a la Insulina/fisiología,
Hígado/patología,
Persona de Mediana Edad,
Cuello/anatomía & histología,
Enfermedad del Hígado Graso no Alcohólico/metabolismo,
Enfermedad del Hígado Graso no Alcohólico/fisiopatología,
Factores Sexuales,
Circunferencia de la Cintura
