ABSTRACT Background: Laparoscopic hepatectomy has presented great importance for treating malignant hepatic lesions. Aim: To evaluate its impact in relation to overall survival or disease free of the patients operated due different hepatic malignant tumors. Methods: Thirty-four laparoscopic hepatectom...
Abstract Purpose: To analyze the use of this sponge in pediatric patients undergoing split-liver transplantation. Methods: Retrospective study, including 35 pediatric patients undergoing split-liver transplantation, divided into two groups according to the use of the sponge: 18 patients in Group A (n...
Fibrinógeno/uso terapéutico,
Hemostasis Quirúrgica/métodos,
Hemostáticos/uso terapéutico,
Trasplante de Hígado/métodos,
Tapones Quirúrgicos de Gaza,
Trombina/uso terapéutico,
Pérdida de Sangre Quirúrgica/prevención & control,
Transfusión de Eritrocitos,
Hepatectomía/métodos,
Hígado/cirugía,
Trasplante de Hígado/efectos adversos,
Reoperación,
Reproducibilidad de los Resultados,
Estudios Retrospectivos,
Estadísticas no Paramétricas,
Herida Quirúrgica/tratamiento farmacológico,
Resultado del Tratamiento
Abstract Purpose: To evaluate the effects of mesenchymal stem cells on liver regeneration in rats following a 70% hepatectomy. Methods: Forty rats were subjected to 70% hepatectomy and then ~106 mesenchymal stem cells (test group), or saline solution (control group), were infused into their livers via ...
Wiederkehr, Henrique de Aguiar;
Wiederkehr, Julio Cesar;
Collaço, Luiz Martins;
Sousa, Eros Luiz de;
Salvalaggio, Paolo;
Carvalho, Caroline Aragão de;
Wiederkehr, Barbara de Aguiar;
Marques, Camila Aparecida Moraes;
Rosa, Francielle França da;
Nanni, Felipe de Negreiros;
Fuchs, Taíse.
ABSTRACT Objective To analyze the influence of portal vein ligation in hepatic regeneration by immunohistochemical criteria. Methods Ten pigs divided into two groups of five animals underwent hepatectomy in two stages, and the groups were differentiated by ligation or not of the left portal vein trib...
Hepatectomía/métodos,
Regeneración Hepática,
Hepatocitos/metabolismo,
Antígeno Ki-67/metabolismo,
Leucocitos,
Ligadura/métodos,
Hígado/patología,
Modelos Animales,
Tejido Parenquimatoso/patología,
Distribución Aleatoria,
Porcinos,
Hígado/cirugía,
Tejido Parenquimatoso/cirugía,
Vena Porta/cirugía
ABSTRACT Introduction: Several factors have made hepatectomy an increasingly safe surgery and new drugs allowed surgical treatment for patients who initially were not candidates for resection. Lesions often require resection, which can be performed by open, laparoscopic, or robotic assisted hepatectomy....
ABSTRACT Background: Partial hepatectomy is a surgical intervention of the liver that can trigger its regenerative process, where the residual lobes deflagrate a compensatory hyperplasia, causing its restoration almost to the original volume. Nevertheless, depending on the extent of liver damage its reg...
Abstract Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively (dissolved in olive oil or in saline soluti...
Antioxidantes/farmacología,
Carotenoides/farmacología,
Hepatectomía/métodos,
Hígado/efectos de los fármacos,
Hígado/cirugía,
Estilbenos/farmacología,
Alanina Transaminasa/sangre,
Apoptosis/efectos de los fármacos,
Aspartato Aminotransferasas/sangre,
Hígado/enzimología,
Hígado/patología,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Estrés Oxidativo/efectos de los fármacos,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
Abstract: Thrombocytopenia has previously been reported after right lobe resection for organ donation. The mechanism(s) of low platelets after right hepatectomy is unclear and several hypotheses have been proposed including a decrease in thrombopoietin, and hepatic insufficiency resulting in relative por...
Hepatectomía/efectos adversos,
Neoplasias Hepáticas/cirugía,
Trasplante de Hígado/efectos adversos,
Donadores Vivos,
Trombocitopenia/etiología,
Hepatectomía/métodos,
Neoplasias Hepáticas/patología,
Trasplante de Hígado/métodos,
Recuento de Plaquetas,
Estudios Retrospectivos,
Factores de Riesgo,
Trombocitopenia/sangre,
Trombocitopenia/diagnóstico,
Factores de Tiempo,
Resultado del Tratamiento
Dedinská, Ivana;
Laca, Ludovit;
Miklusica, Juraj;
Palkoci, Blazej;
Skálová, Petra;
Lauková, Slavomíra;
Osinová, Denisa;
Strmenová, Simona;
Janík, Ján;
Mokán, Marián.
Abstract: Introduction and aims. Liver resection is the treatment of choice for many primary and secondary liver diseases. Most studies in the elderly have reported resection of primary and secondary liver tumors, especially hepatocellular carcinoma and colorectal metastatic cancer. However, over the l...
Ablación por Catéter/efectos adversos,
Hepatectomía/efectos adversos,
Neoplasias Hepáticas/cirugía,
Complicaciones Posoperatorias/epidemiología,
Factores de Edad,
Ablación por Catéter/mortalidad,
Distribución de Chi-Cuadrado,
Hepatectomía/métodos,
Hepatectomía/mortalidad,
Incidencia,
Estimación de Kaplan-Meier,
Neoplasias Hepáticas/mortalidad,
Neoplasias Hepáticas/patología,
Análisis Multivariante,
Selección de Paciente,
Complicaciones Posoperatorias/diagnóstico,
Complicaciones Posoperatorias/mortalidad,
Modelos de Riesgos Proporcionales,
Estudios Retrospectivos,
Medición de Riesgo,
Factores de Riesgo,
Factores de Tiempo,
Eslovaquia,
Resultado del Tratamiento
ABSTRACT Background: Surgical strategy to increase the number of liver transplants in the pediatric population is the ex-situ liver transection (reduction or split). However, it is associated with complications such as hemorrhage and leaks. The human fibrinogen and thrombin sponge is useful for improvin...