Results: 46

Stroke at baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): a cross-sectional analysis

Säo Paulo med. j; 136 (5), 2018
ABSTRACT BACKGROUND: Secondary prevention of stroke is a very important goal for achieving continuous reduction in stroke mortality rates over the next decades. DESIGN AND SETTING: Cross-sectional analysis on the Brazilian Longitudinal Study of Adult Health ­(ELSA-Brasil), with data from Salvador, V...

Una nueva clase de fármacos hipolipemiantes reduce la incidencia de infartos miocárdicos y cerebrales
A new class of lipid-lowering drugs reduces myocardial and stroke

Effect of ischemic postconditioning and atorvastatin in the prevention of remote lung reperfusion injury

Abstract Objective: The aim of the present study was to evaluate the ability of ischemic postconditioning, atorvastatin and both associated to prevent or minimize reperfusion injury in the lung of rats subjected to ischemia and reperfusion by abdominal aortic clamping. Methods: We used 41 Wistar norveg...

Statins and bonehealth: a mini review

Actual. osteol; 14 (1), 2018
Statins are a widely prescribed class of medications that inhibit similar pathways as the anti-resorptive bisphosphonate drugs. Statins target the mevalonate pathway by blocking HMG-CoA reductase. Several recent meta-analyses concluded statins are osteoprotective in the general population. Here we presen...

Atorvastatin can prevent hepatic remote reperfusion injury

ABCD (São Paulo, Impr.); 30 (3), 2017
ABSTRACT Background: Some studies have shown that statins have a promising effect on protection against reperfusion injury. Aim: To evaluate the ability of ischemic postconditioning, statins and both associated to prevent or minimize reperfusion injury in the liver of rats subjected to ischemia and rep...

Patient adherence to ischemic heart disease treatment

Summary Introduction: The effectiveness of the treatment of chronic diseases depends on the participation of the patient, influenced by different sociocultural factors, which are not fully recognized by the treatment routine. Objective: To search for some of these factors that hinder or facilitate adhe...

El tratamiento con estatinas para bajar el colesterol es seguro y efectivo en el largo plazo

Indicar estatinas a personas con riesgo cardiovascular global de 7, 5% a diez años es costo-efectivo en los EEUU
Indicating statins for people with a global cardiovascular risk of 7,5% at ten years is cost-effective in the USA

El objetivo de C-LDL <70 mg/dL no se asoció con un mayor beneficio en pacientes con enfermedad coronaria estable tratados con estatinas
The LDL-C <70 mg /dL goal was not associated with a greater benefit in patients with stable coronary artery dis-ease treated with statins