Results: 103

Thalidomide reduces cell proliferation in endometriosis experimentally induced in rats

Abstract Objective To analyze the effect of thalidomide on the progression of endometriotic lesions experimentally induced in rats and to characterize the pattern of cell proliferation by immunohistochemical Proliferating Cell Nuclear Antigen (PCNA) labeling of eutopic and ectopic endometrium. Methods...

Acute bilateral Irvine-Gass Syndrome following uneventful cataract surgery in a patient without systemic risk factors

Rev. bras. oftalmol; 78 (5), 2019
Abstract We herein report a patient without risk factors who presented acute bilateral Irvine-Gass syndrome after uneventful phacoemulsification. The novelty of our case lies on the fact that the patient presented acute bilateral Irvine-Gass syndrome without a predisposing systemic disease. Even though C...

The tale of lenalidomide clinical superiority over thalidomide and regulatory and cost-effectiveness issues

Abstract In April 2017, the National Sanitary Surveillance Agency (ANVISA-Brazil) approved lenalidomide (LEN) for multiple myeloma (MM) and myelodysplastic syndrome. ANVISA had rejected the first application in 2010, and denied a request for reconsideration in 2012. The reason for rejection was the lack ...

Acquired hemophilia in an elderly person

Acta méd. colomb; 44 (3), 2019
Abstract Acquired hemophilia is a rare but highly fatal hemostatic disorder that occurs predominantly in elderly people. It is a disorder secondary to the development of specific autoantibodies directed against coagulation factor VIII. It is characterized by potentially fatal gastrointestinal, pulmonary,...

Effectiveness of monthly and fortnightly anti-VEGF treatments for age-related macular degeneration

Arq. bras. oftalmol; 82 (3), 2019
ABSTRACT Purpose: To study the efficacy and safety of treatments with ranibizumab and bevacizumab for exudative age-related macular degeneration. Methods: A parallel randomized clinical trial was conducted to compare the efficacy and safety of three regimens (bevacizumab every month, bevacizumab every ...

Effects of ranibizumab and amfenac on the functional abilities and radiosensitivity of uveal melanoma cells

Arq. bras. oftalmol; 82 (1), 2019
ABSTRACT Purpose: To evaluate the effects of ranibizumab and amfenac in human uveal melanoma cell lines and to explore the ability of these compounds to sensitize uveal melanoma cells to radiation therapy. Methods: The 92.1 human uveal melanoma cell line was cultured and subjected to the proposed tre...

Guía de práctica clínica para el diagnóstico y tratamiento de la degeneración macular relacionada a la edad: guía en versión extensa

Brindar recomendaciones y puntos de buenas prácticas clínicas basadas en evidencia para el adecuado diagnóstico y tratamiento de los pacientes con degenaración macular relacionada con la edad (DMRE), contestando a las siguientes preguntas: a) En personas mayores de 50 años, ¿cómo se debería diagn...

Risk profile for antiangiogenic agent-related osteonecrosis of the jaws

Einstein (Säo Paulo); 17 (3), 2019
ABSTRACT To establish the profile of patients who developed antiangiogenic agent-related osteonecrosis of the jaws, and identify the treatments currently used in dental management. We searched the PubMed®/Medline® and Scopus databases using the words "osteonecrosis AND antiangiogenic therapy", with the...

Efecto del uso preoperatorio de bevacizumab intravítreo en pacientes con retinopatía diabética proliferativa sometidos a vitrectomía- Primera actualización

Medwave; 19 (1), 2019
ACTUALIZACIÓN: Este resumen Epistemonikos (Living FRISBEE: Living FRIendly Summary of the Body of Evidence using Epistemonikos) es una actualización del resumen publicado en diciembre de 2014. INTRODUCCIÓN: La retinopatía diabética proliferativa conlleva un alto riesgo de ceguera si no es tratada d...

Efecto antiangiogénico de la triamcinolona asociada a lidocaína con epinefrina de uso odontológico en la membrana alantocoriónica de pollo

Int. j. morphol; 37 (1), 2019
RESUMEN: El proceso angiogénico se define como el proceso en el que los vasos sanguíneos generan brotes dando como resultado neovascularidad. Un desbalance en el proceso angiogénico contribuye a numerosos desórdenes inflamatorios, infecciosos, isquémicos, inmunológicos y malignos. En el territorio ...