Results: 68

Variability in innate host immune responses to cryptococcosis

Mem. Inst. Oswaldo Cruz; 113 (7), 2018
Cryptococcosis is an invasive fungal disease caused by Cryptococcus neoformans and the closely related species C. gattii. The severe form of the disease, cryptococcal meningitis (CM), is rapidly fatal without treatment. Although typically a disease of immunocompromised (especially HIV-positive) individua...

Polimorfismos genéticos asociados a la inmunidad innata y la susceptibilidad genética a la tuberculosis

Resumen La tuberculosis es un problema de salud mundial exacerbado por la ausencia de una vacuna eficaz y la emergencia de cepas multidrogo resistentes. La inmunidad innata, clave en la susceptibilidad a tuberculosis, está asociada a polimorfismos genéticos en TLRs (Toll Like Receptors), VDR (Vitamin D...

Activity of Brazilian propolis against Aeromonas hydrophila and its effect on Nile tilapia growth, hematological and non-specific immune response under bacterial infection

An. acad. bras. ciênc; 89 (3), 2017
ABSTRACT The effect of the ethanolic extract of propolis (EEP) on Aeromonas hydrophila was analyzed by determination of minimum inhibitory concentration (MIC). Then, the effects of crude propolis powder (CPP) on growth, hemato-immune parameters of the Nile tilapia, as well as its effects on resistance to...

Uma nova classe de doenças: doenças autoinflamatórias

As doenças autoinflamatórias sistêmicas são um grupo de doenças raras recentemente descritas, mas que vêm ganhando espaço no cenário clínico. Caracterizam-se por alterações da imunidade inata, portanto sem a presença de linfócito T autorreator ou autoanticorpo, e que respondem ao bloqueio de...

Haplotypes in CCR5-CCR2 , CCL3 and CCL5 are associated with natural resistance to HIV-1 infection in a Colombian cohort

Biomédica (Bogotá); 37 (2), 2017
RESUMEN Introduction: Variants in genes encoding for HIV-1 co-receptors and their natural ligands have been individually associated to natural resistance to HIV-1 infection. However, the simultaneous presence of these variants has been poorly studied. Objective: To evaluate the association of single a...

Papel de las células dendríticas en la infección por el virus dengue: blancos de replicación y respuesta inmune

Rev. chil. infectol; 34 (3), 2017
Dengue fever, caused by dengue virus (DENV) infection, is one of the most important diseases in the world, not only due to the high morbidity/mortality rates it causes, but also because of its great economic and social impact in tropical/subtropical countries. DENV infection has a wide range of clinical ...

Influence of orchiectomy of seven month old bulls on bronchoalveolar immune function

The present study evaluated the impact that orchiectomy, a routine but painful intervention in bovine husbandry, can cause on pulmonary immunity. To identify whether orchiectomy can impair lung defense, analyses of serum cortisol concentration and of alveolar macrophage and their function (phagocytosis a...

Doenças autoinflamatórias em adultos: abordagem prática ao diagnóstico baseada em um caso clínico

As doenças autoinflamatórias são doenças inflamatórias raras cujo cerne imunológico baseia-se na imunidade inata. A maioria das doenças autoinflamatórias tem início na idade pediátrica, mas pouco se sabe sobre as doenças que se iniciam na vida adulta. O diagnóstico é feito por exclusão, e, ...

Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cells

J. appl. oral sci; 25 (1), 2017
Abstract IL-10 expressing regulatory B cells (B10) play a key role in immune system balance by limiting excessive inflammatory responses. Effects of toll-like receptor signaling and co-stimulatory molecules on B10 activity during innate and adaptive immune responses are not fully understood. Objective ...