Abstract This study analyzed the antifungal activity of phytoconstituents from linalool on Candida spp. strains, in vitro, isolated from patients with clinical diagnoses of oral candidiasis associated with the use of a dental prosthesis. Biological samples were collected from 12 patients using complete d...
The aim of this study was to evaluate the antifungal activity (in vitro) of thymol and carvacrol alone or in mixtures against Fusarium verticillioides and Rhizopus stolonifer, and to obtain primary growth models. Minimal inhibitory concentration (MIC) was evaluated with fungal radial growth with thymol o...
ABSTRACT The present study investigated the effects of carvacrol on motor and memory deficits as well as hyperalgesia in the 6-OHDA-lesioned rat model of Parkinson's disease. The animals were subjected to unilateral microinjection of 6-OHDA into the medial forebrain bundle and treated with carvacrol (25,...
Antioxidantes/farmacología,
Antioxidantes/uso terapéutico,
Antiparkinsonianos/farmacología,
Antiparkinsonianos/uso terapéutico,
Cimenos,
Modelos Animales de Enfermedad,
Peroxidación de Lípido/efectos de los fármacos,
Trastornos de la Memoria/tratamiento farmacológico,
Trastornos de la Memoria/fisiopatología,
Memoria a Corto Plazo/efectos de los fármacos,
Monoterpenos/farmacología,
Monoterpenos/uso terapéutico,
Actividad Motora/efectos de los fármacos,
Neuralgia/tratamiento farmacológico,
Neuralgia/fisiopatología,
Oxidopamina,
Enfermedad de Parkinson/tratamiento farmacológico,
Enfermedad de Parkinson/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Compuestos de Sulfhidrilo/análisis
Clinopodium gilliesii (Benth.) Kuntze, harvested in the Chilean highlands, contains a surprising 93.87% of the toxic monoterpene pulegone in the essential oil. These results show remarkable differences with studies of the same species carried out in Argentina and Peru. These dissimilarities in the monote...
Abstract INTRODUCTION Citronellal (Cit) possesses antifungal activity and has possible implications for reactive oxygen species (ROS) generation in Candida albicans. In this study, the effects of Cit on ROS generation and the mechanisms by which Cit exerts anti-Candida effects were examined. METHODS ...
ABSTRACT Linalool is the main compound of many essential oils and occurs in two isomeric forms: S-(+)- and R-(-)-linalool. This study aimed to determine if linalool isomers have different antimicrobial and anesthetic properties in fish. For this purpose, these compounds were previously isolated from Lipp...
Monoterpenos Acíclicos,
Aeromonas hydrophila/efectos de los fármacos,
Anestésicos/farmacología,
Antibacterianos/farmacología,
Bagres,
Hipnóticos y Sedantes/farmacología,
Lippia/química,
Pruebas de Sensibilidad Microbiana,
Monoterpenos/química,
Monoterpenos/aislamiento & purificación,
Monoterpenos/farmacología,
Ocimum/química,
Aceites Volátiles/química,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estereoisomerismo,
Factores de Tiempo
ABSTRACT INTRODUCTION: Schistosomiasis, a parasitic disease caused by trematode flatworms of the genus Schistosoma, affects more than 200 million people worldwide, and its control is dependent on a single drug, praziquantel. Here, we report the in vitro effect of rotundifolone, a monoterpene isolated f...
Abstract This study evaluated the removal of filling material with ProTaper Universal Rotary Retreatment system (PTR) combined with solvents and the influence of solvents on the bond strength (PBS) of sealer to intraradicular dentin after canal reobturation. Roots were endodontically treated and distribu...
Análisis de Varianza,
Ciclohexanoles/química,
Recubrimiento Dental Adhesivo,
Instrumentos Dentales,
Cavidad Pulpar/efectos de los fármacos,
Dentina/efectos de los fármacos,
Resinas Epoxi/química,
Gutapercha,
Ensayo de Materiales,
Microscopía Electrónica de Rastreo,
Monoterpenos/química,
Aceites de Plantas/química,
Reproducibilidad de los Resultados,
Retratamiento/instrumentación,
Materiales de Obturación del Conducto Radicular/química,
Preparación del Conducto Radicular/instrumentación,
Preparación del Conducto Radicular/métodos,
Solventes/química
Abstract: INTRODUCTION There is an increasing burden of multidrug resistance. As a result, deciphering the mechanisms of action of natural compounds with antifungal activity has gained considerable prominence. We aimed to elucidate the probable mechanism of action of citronellal, a monoterpenoid found ...
Monoterpenos Acíclicos,
Aldehídos/farmacología,
Antifúngicos/farmacología,
Biopelículas/efectos de los fármacos,
Biopelículas/crecimiento & desarrollo,
Candida albicans/efectos de los fármacos,
Candida albicans/patogenicidad,
Adhesión Celular/efectos de los fármacos,
Homeostasis/efectos de los fármacos,
Pruebas de Sensibilidad Microbiana,
Monoterpenos/farmacología,
Virulencia/efectos de los fármacos
Introduction: Pediculosis capitis is a public health problem with a high prevalence. The emergence of parasite resistance to conventional pediculicide is of great concern worldwide. Objective: To develop alternatives pediculicide, effective and safe, based on the essential oil of Eucaliptus globulus. Met...
