ABSTRACT Background: Melanocytic lesions of the central nervous system (CNS) are an infrequent, broad and diverse group of entities, both benign and malignant, found in all age groups, with imaging findings ranging from well-circumscribed focal lesions to diffuse leptomeningeal involvement. On MRI, the...
Abstract Background: Infantile hemangiomas (IH) occur in approximately 4% to 10% of the pediatric population. The identification of clinical subtypes and conditions that indicate increased risk for complications is essential for therapeutic success. Objectives: To identify risk factors for complication...
Abstract Basaloid follicular hamartoma is a benign, superficial malformation of hair follicles that can be mistaken both clinical and histopathologically for basal cell carcinoma. Basaloid follicular hamartoma has been linked to a mutation in the PTCH-1 gene, which is part of the same pathway involved in...
Abstract The continuous prolonged exposures of sun light especially the ultra violet (UV) radiation present in it, cause not only the risk of skin cancer but also it may cause premature skin aging, photodermatoses and actinic keratoses. Flavonoids (including Flavane, Flavanone, Flavone, Flavonol, Isoflav...
Rayos Ultravioleta/efectos adversos,
Enfermedades de la Piel/tratamiento farmacológico,
Quercetina/análisis,
Flavonoides/efectos adversos,
Antioxidantes/clasificación,
Queratosis Actínica/patología,
Fitoquímicos/análisis,
Factores Protectores,
Neoplasias Cutáneas/patología,
Piel/lesiones,
Preparaciones Farmacéuticas/análisis
Melanoma accounts for 3% of skin neoplasms and is the leading cause of death from skin disorders worldwide. The high mortality rate associated with this disease stems from the high capacity of melanoma patients to develop metastases and treatment relapse with inhibitors of the MAPK signaling pathway (suc...
Melanoma/patología,
Neoplasias Cutáneas/complicaciones,
Piel,
Absentismo,
Análisis de Secuencia de ARN/instrumentación,
Biología Computacional/métodos,
Biomarcadores/análisis,
Expresión Génica,
Metodología como un Tema,
Metástasis de la Neoplasia,
Neoplasias,
Pacientes/clasificación,
Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas,
Supervivencia Celular,
Técnicas In Vitro/métodos
O câncer de pele pode ser classificado como não melanoma e melanoma. O melanoma apresenta baixa incidência entre os cânceres de pele, porém é a forma mais letal e é considerado um dos tipos mais resistentes ao tratamento. Devido à infiltração de células malignas nos tecidos, vasos linfáticos ...
Introdução: A associação de leucemia linfocítica crônica (LLC) e
melanoma tem sido estudada nos últimos anos. Acredita-se que a
imunossupressão causada pelo tratamento da doença seja o fator de risco
mais importante para o aumento da susceptibilidade ao desenvolvimento
e disseminação do cânce...
Resumen: Introducción: el subtipo histopatológico es uno de los determinantes fundamentales en la clasificación de riesgo de los carcinomas cutáneos. Surge de una biopsia incisional que representa solo un porcentaje de la masa tumoral, siendo la principal preocupación la no detección de un subtipo ...
Introduction: Non-melanoma skin cancer (NMSC) is the most common among all malignancies. Objective: To describe trends in NMSC mortality rates in Brazil and its macroregions from 2001 to 2018. Method: Adjusted mortality rates stratified by sex were estimated and presented per 100,000 person-years. An aut...