Results: 123

Cáncer de próstata y polimorfismos de la glutation s-transferasa en una población venezolana
Prostate cancer and polymorphisms of the glutathione s-transferase in a population Venezuelan

En vista de la alta prevalencia del cáncer de próstata en la población venezolana y la ausencia de un patrón genético conocido en relación a la expresión de las enzimas Glutatión S-transferasas, se estudió la relación entre la expresión de un polimorfismo nulo de estas enzim...

Second brazilian consensus on the treatment of advanced prostate cancer: a SBOC-SBU-SBRT panel review

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Prostate cancer is the second most common cancer and the fifth leading cause of cancer deaths. In Brazil, it is likewise the second most common cancer among men, second only to non-melanoma skin cancers. The aim of this consensus is to align different opinions and interpretations of the medical ...

Enhancing PSMA-uptake with androgen deprivation therapy - a new way to detect prostate cancer metastases?

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Purpose: 68Ga-PSMA PET/CT imaging is a promising modality for the staging of recurrent prostate cancer (PCa). Current evidence suggests limited diagnostic value of the 68Ga-PSMA PET/CT in PSA-levels ≤0.3ng/mL. Experimental data have demonstrated an increase in PSMA-expression in PCa metas...

Impact of time from biopsy to surgery on complications, functional and oncologic outcomes following radical prostatectomy

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Introduction: To determine the impact of time from biopsy to surgery on outcomes following radical prostatectomy (RP) as the optimal interval between prostate biopsy and RP is unknown. Material and methods: We identified 7, 350 men who underwent RP at our institution between 1994 and 2012 and ...

Impact of PI-RADS v2 on indication of prostate biopsy

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Objectives: To identify the group of patients who could safely avoid prostate biopsy based on the findings of multiparametric prostate resonance imaging (MRmp), parameterized with PI-RADS v2, using prostate biopsy as reference test and to assess the sensitivity and specificity of mpMR in identi...

Cáncer de próstata, el problema del diagnóstico: ¿es la resonancia multiparamétrica de próstata la solución?

Rev. chil. radiol; 25 (2), 2019
Junto con un aumento sostenido en la incidencia de cáncer de próstata en los países desarrollados ha habido un cambio en el enfrentamiento diagnóstico en estos pacientes. El diagnóstico tradicional basado en la medición del antígeno prostático específico y la biopsia randomizada ha mostrado tene...

Salvage radiotherapy for biochemical recurrence after radical prostatectomy: does the outcome depend on the prostate cancer characteristics?

Int. braz. j. urol; 45 (2), 2019
ABSTRACT Objective: To build a model to evaluate the impact of salvage radiotherapy (SRT) in men with PSA rise or persistent PSA after undergoing radical prostatectomy (RP). Materials and Methods: The study included 107 node-negative patients treated with SRT after RP at a single institution. Patients ...

Prostate brachytherapy with iodine-125 seeds: analysis of a single institutional cohort

Int. braz. j. urol; 45 (2), 2019
ABSTRACT Objectives: Brachytherapy (BT) with iodine-125 seeds placement is a consolidated treatment for prostate cancer. The objective of this study was to assess the clinical outcomes in patients with prostate cancer who underwent low-dose-rate (LDR) -BT alone in a single Brazilian institution. Materi...

Is moderate hypofractionation accepted as a new standard of care in north america for prostate cancer patients treated with external beam radiotherapy? Survey of genitourinary expert radiation oncologists

Int. braz. j. urol; 45 (2), 2019
ABSTRACT Introduction: Several recent randomized clinical trials have evaluated hypofractionated regimens against conventionally fractionated EBRT and shown similar effectiveness with conflicting toxicity results. The current view regarding hypofractionation compared to conventional EBRT among North Ame...