Background: In this work, the xylanase production by Penicillium chrysogenum F-15 strain was investigated using agroindustrial biomass as substrate. The xylanase was purified, characterized and applied in hemicellulose hydrolysis. Results: The highest xylanase production was obtained when cultivation was...
Endo-1,4-beta Xilanasas/biosíntesis,
Penicillium chrysogenum/metabolismo,
Endo-1,4-beta Xilanasas/aislamiento & purificación,
Electroforesis en Gel de Poliacrilamida,
Estabilidad de Enzimas,
Concentración de Iones de Hidrógeno,
Temperatura,
Biomasa,
Hidrólisis,
Polisacáridos/metabolismo
ABSTRACT Soybeans contain about 30% carbohydrate, mainly consisting of non-starch polysaccharides (NSP) and oligosaccharides. NSP are not hydrolyzed in the gastrointestinal tract of monogastric animals. These NSP negatively affect the development of these animals, especially the soluble fraction. This wo...
L-amino acid oxidases isolated from snake venoms (SV-LAAOs) are enzymes that have great therapeutic potential and are currently being investigated as tools for developing new strategies to treat various diseases, including cancer and bacterial infections. The main objective of this study was to make a br...
A ingestão regular de fibras alimentares pode auxiliar na redução do risco de certas doenças crônicas, como doenças cardiovasculares, síndromes metabólicas, diabetes tipo 2 e alguns tipos de câncer. Dentre as principais fontes de fibras alimentares, destaca-se o grão de trigo, que é rico em fi...
A bactéria gram-positiva Streptococcus agalactiae do grupo B (GBS) faz parte da microbiota normal do trato geniturinário humano, sendo um organismo comensal do corpo da mulher. No entanto, em mulheres grávidas, quando há alterações na composição microbiana do canal vaginal, pode ocorrer a prolife...
Cuscuta chinensis polysaccharide (CPS) was extracted using hot water and enzymatically hydrolyzed C. chinensis polysaccharide (ECPS) was produced by the mannase enzymatic hydrolysis process. The purpose of this research was to investigate the antimelanogenic activity of ECPS and CPS in B16F10 melanoma ce...
Antineoplásicos Fitogénicos/farmacología,
Antioxidantes/química,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Línea Celular Tumoral,
Cuscuta/química,
Hidrólisis,
Melanocitos/efectos de los fármacos,
Melanoma Experimental/patología,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Polisacáridos/química,
Polisacáridos/aislamiento & purificación,
Polisacáridos/farmacología,
Semillas/química
ABSTRACT Linseed hydrogel (LSH) was evaluated by acute toxicity for its potential application in oral drug delivery design. White albino mice and rabbits were divided in four groups (I-IV) and different doses of LSH (1, 2 and 5 g/kg body weight) were given except to the control group (I) that was left un...
Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the environment. It causes a deadly meningitis that is responsible for over 180,000 deaths worldwide each year, including 15% of all AIDS-related deaths. The high mortality rates for this infection, even with treatment, sug...
Andrade, Paula Durante;
Russo, Joice de Souza;
Gouveia, Jéssica Baliero;
Costa, Cláudia Raquel Cantarelli;
Oliveira, Ketti Gleyzer;
Gianetti, Michelli;
Anjos, Emanuel Borges Vítor;
Pavan, Tycha Bianca Sabaini;
Martins, Mariana Furquim Da Silva;
Franco, Josiele;
Costa, Maria Laura;
Nomura, Marcelo Luís;
Levy, Carlos Emílio;
Passini Júnior, Renato;
Costa, Sandra Cecilia Botelho.
OBJECTIVE: Group B Streptococcus (GBS) serotypes (Ia, Ib and II to IX) are classified based on variations in their capsular polysaccharide; their prevalence differs between different geographic areas. We examined the prevalence of all GBS serotypes in rectal and vaginal swab samples obtained from 363 pre...
Pharmacological efficacy of Caulerpa racemosa (Chlorophyta) sulfated polysaccharidic (SPs) fractions (F I→III) on models of coagulation and inflammation has been demonstrated, but not their effects on thrombin generation (TG). This study examined fractions for composition and physical-chemical characte...
