Results: 189

Biochemical characterization of the recombinant schistosome tegumental protein SmALDH_312 produced in E. coli and baculovirus expression vector system

BACKGROUND The heterologous expression of parasitic proteins is challenging because the sequence composition often differs significantly from host preferences. However, the production of such proteins is important because they are potential drug targets and can be screened for interactions with new lead ...

Reactive aqueous two-phase systems for the production and purification of PEGylated proteins

BACKGROUND PEGylation, defined as the covalent attachment of polyethylene glycol, allows the synthesis of PEGylated therapeutic proteins with enhanced physicochemical properties. Traditional alkylating Nterminal PEGylation reactions on amine groups involve the use of modified linear mono-methoxy polyethy...

Biomarcadores en tuberculosis

Resumen Los métodos diagnósticos clásicos para la tuberculosis son de baja sensibilidad o son muy lentos en la obtención de resultados (baciloscopía, cultivo de Koch). De ahí nace la necesidad de nuevos métodos diagnósticos para esta enfermedad. Los biomarcadores surgen como una opción a esta pr...

Niveles séricos de interleucina-6 en pacientes con diabetes tipo 2 y su correlación con el perfil lipídico

La diabetes mellitus es una enfermedad metabólica caracterizada por hiperglucemia, a consecuencia de defectos en la producción, secreción y/o acción de la insulina, produciendo alteraciones en el metabolismo de los hidratos de carbono, lípidos y proteínas; asociado a un proceso inflamatorio crónic...

Síndrome de enterocolite induzida por proteína alimentar como diagnóstico diferencial das alergias alimentares: relato de caso

A síndrome da enteropatia induzida por proteína alimentar, aguda ou crônica, é um tipo de alergia alimentar não mediada por IgE, que surge entre os 5 e 9 meses de idade, e é caracterizada por episódios de vômitos que começam aproximadamente 1 a 4 horas após a ingestão do alérgeno, algumas vez...

Molecular sensitization profile of patients with lipid transfer protein syndrome and associated clinical characteristics

Introduction: Lipid transfer proteins (LTPs) can cause a diversity of food allergy phenotypes, broadly defined as LTP syndrome. Objective: The aims of this study were to characterize the molecular profile of patients with this syndrome and to evaluate any possible association with clinical phenotypes. Me...

Cow's milk protein allergy, quality of life and parental style

INTRODUCTION: Cow's milk protein allergy requires changes in family habits to maintain children's health. OBJECTIVE: This study evaluated the effects of cow's milk protein allergy on the health of children, the quality of life of parents and children, and the adopted parental styles. METHODS: Control cas...

Soporte nutricional y cumplimiento de objetivos nutricionales en la UCI Pediátrica del Hospital Metropolitano

Metro cienc; 29 (1 (2021): Enero- Marzo), 2021
RESUMEN Objetivos: Describir el soporte nutricional que se administra en la UCI Pediátrica del Hospital Metropolitano y evaluar nuestra capacidad de alcanzar los objetivos nutricionales recomendados en guías clínicas internacionales. Métodos: Análisis retrospectivo de datos recolectados ...

Proteínas importantes para la invasión de Babesia bovis a las células huésped

Introducción: La babesiosis bovina es causada por parásitos Apicomplexa del género Babesia, siendo la Babesia bovis la especie asociada con cuadros clínicos más graves de la enfermedad. La invasión de B. bovis a los eritro-citos bovinos implica la interacción entre moléculas de los merozoítos de...

Isolation and characterization of antihypertensive peptides from soy bean protein

Proteins and peptides are the most diverse biomolecules found in nature and make our interest due to their wide applications in food and pharmaceutical industry. Angiotensin Converting Enzyme (ACE) plays a major role in controlling blood pressure. The inhibition of ACE with peptides is a main target in t...