Results: 496

Correlación entre el umbral de ciclo de la RPC en tiempo real y la clasificación clínica de la COVID-19

Rev. chil. infectol; 39 (1), 2022
INTRODUCCIÓN: El umbral de ciclo (en inglés cycle threshold-Ct) de la reacción de polimerasa en cadena en tiempo real con transcripción reversa (RT-qPCR) indica la concentración relativa de una secuencia de ARN; este valor se ha relacionado con la expresión de cuadros clínicos en infecciones viral...

Effects of nitric oxide on C2C12 cell inflammatory responses and notexin-induced muscle injury

Int. j. morphol; 40 (1), 2022
SUMMARY: Skeletal muscle injury is an acute inflammatory condition caused by an inflammatory response. To reduce inflammatory cell infiltration and relieve skeletal muscle injury, efficient treatment is urgently needed. Nitric oxide is a free radical molecule reported to have anti-inflammatory effects. I...

Avaliação da infecção por Parvovírus Humano B19 em diferentes grupos populacionais: diagnóstico diferencial e aspectos imunopatogênicos da infecção aguda e persistente

A infecção pelo Parvovírus B19 (B19V) pode ocorrer em indivíduos imunocompetentes e imunocomprometidos, de todas as faixas etárias, e se caracteriza por ser aguda e autolimitada, podendo levar a quadros de doença exantemática (DE), doença febril aguda (DFA), doença renal crônica (DRC) e falênc...

Validation of a one-tube nested real-time PCR assay for the detection of Cryptosporidium spp. in avian fecal samples

Abstract The aim of this study was to validate a one-tube nested real-time PCR assay followed by genetic sequencing to detect and identify Cryptosporidium species and genotypes in birds. A total of 443 genomic DNA extracted from avian fecal samples were analyzed by one-tube nested real-time PCR and conve...

Estudo exploratório da Síndrome Hipoplasia Cartilagem-Cabelo no Brasil: uma abordagem genômica, proteômica e de análise estrutural de RNA
Exploratory study of Hypoplastic Cartilage-Hair Syndrome in Brazil: a genomic, proteomic and RNA structural analysis approach

A Hipoplasia Cartilagem-Cabelo (do inglês, Cartilage Hair Hypoplasia; CHH) é uma doença autossômica recessiva descrita por McKusick et al., em 1964 em crianças da comunidade Amish. Clinicamente, os pacientes apresentam displasia óssea metafisária em diferentes graus de gravidade. Além disso, tamb...

Detección del SARS-CoV-2 mediante RT-qPCR utilizando saliva en pacientes ambulatorios con estudio de COVID-19

Rev. chil. infectol; 39 (4), 2022
INTRODUCCIÓN: La pandemia de COVID-19 ha afectado a millones de personas en todo el mundo. La identificación de sujetos infectados ha sido importante para el control. OBJETIVO: Evaluar el rendimiento de una reacción de polimerasa en cadena (RPC) cuantitativa en tiempo real (en inglés: RT-qPCR) para S...

Meningitis tuberculosa: un desafío diagnóstico en pediatría

Rev. chil. infectol; 39 (4), 2022
Resumen La meningitis por Mycobacterium tuberculosis es infrecuente en pediatría y su diagnóstico definitivo representa un desafío clínico. Presentamos el caso de un lactante de dos años, que presentó un cuadro de meningitis crónica. Se logró el diagnóstico tras la sospecha imagenológica y la c...

Clinical validation of an in-house quantitative real time PCR assay for cytomegalovirus infection using the 1st WHO International Standard in kidney transplant patients

J. bras. nefrol; 43 (4), 2021
Abstract Introduction: Cytomegalovirus (CMV) is one of the most common agents of infection in solid organ transplant patients, with significant morbidity and mortality. Objective: This study aimed to establish a threshold for initiation of preemptive treatment. In addition, the study compared the perfo...

Expression of myosin heavy chain isoform mRNA transcripts in the masseter and medial pterygoid muscles

Int. j. morphol; 39 (5), 2021
SUMMARY: Both the masseter and medial pterygoid muscles elevate the mandible, raising the lower jaw by acting simultaneously on the lateral and medial surfaces of the mandibular ramus. Nevertheless, electromyographic studies indicate that these muscles, as well as the superficial and deep heads of the ma...

Urological Cancer Treatment by a Multidisciplinary Teamthroughout the Covid-19 Pandemic: What Have We Learned?

Introduction It is known that cancer care is best approached by a multidisciplinary team (MDT). This became specifically true in the Covid-19 pandemic in which choices for urological cancer treatment are influenced by many factors. In some cases, delayed treatment may have consequences regarding the pati...