Results: 467

A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism

ABSTRACT Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and sympt...

A Prospective Cohort Study on Cardiotoxicity of Adjuvant Trastuzumab Therapy in Breast Cancer Patients

Arq. bras. cardiol; 107 (1), 2016
Abstract Background: Cardiotoxicity is an important side effect of trastuzumab therapy and cardiac surveillance is recommended. Objectives: The aim of our study was to prospectively assess baseline patients' characteristics, level of N-terminal pro-brain natriuretic peptide (NT-proBNP) and echocardiogr...

Prolactinomas may have unusual presentations resulting from massive extrasellar tumor extension

Arq. neuropsiquiatr; 74 (7), 2016
ABSTRACT The purpose of this case series is to report eight patients with giant prolactinomas emphasizing presentations and a treatment complication. The study group included six men and two women. The median age was 29 years (18–54 years); median serum prolactin level was 4,562 ng/ml (1,543–...

Consumo alimentar e estado nutricional de mulheres em quimioterapia

Resumo O objetivo deste estudo foi analisar o consumo alimentar e o estado nutricional de mulheres com câncer de mama (CM) em quimioterapia (QT). A avaliação dietética quantitativa foi realizada de acordo com as Dietary Reference Intakes (DRI) e a avaliação qualitativa pelo Índice de Qualidade da ...

Qualidade de vida de pacientes durante terapia antineoplásica: estudo descritivo

OBJETIVO: avaliar a qualidade de vida de pacientes oncológicos que utilizam dispositivo para infusão contínua de antineoplásicos. MÉTODO: estudo transversal, realizado em uma operadora de plano de saúde de Fortaleza/CE, em 2013, com 28 pacientes, mediante aplicação do instrumento de avaliação d...

¿Cómo tratar las leucemias mieloides agudas (LMA) en mayores de 60 años?
How to treat acute myeloid leukemias (AML) in over 60 years old?

Seguridad y eficacia del sorafenib en el carcinoma renal metastasico avanzado que progresa despues del tratamiento de primera linea con sunitinib

INTRODUCCIÓN: Antecedentes: El presente informe expone la evaluación del medicamento sorafenib a su uso, en pacientes con carcinoma renal metastásico que progresa al tratamiento de primera línea con sunitinib. Aspectos Generales: El carcinoma de células renales (CCR) es un tipo de cáncer del riñon...

PEG-asparaginase induced severe hypertriglyceridemia

Asparaginase (ASP) is an effective chemotherapy agent extensively used in children with acute lymphocytic leukemia (ALL). There has been a recent interest in using ASP in adults with ALL, particularly the less toxic pegylated (PEG) formulation. Hypertriglyceridemia (HTG) is a rare complication of PEG-ASP...

Variables condicionantes del tratamiento en pacientes añosos con leucemia mieloide aguda: Experiencia institucional
Treatment conditioning variables in elderly patients with acute myeloid leukemia. An institutional experience

Medicina (B.Aires); 76 (2), 2016
Los mayores de 60 años con leucemia mieloide aguda (LMA) tienen peor pronóstico que el resto de los pacientes. En la literatura se expresan diferentes factores que podrían condicionar su supervivencia. Se propuso determinar cuáles fueron los principales determinantes de supervivencia global en nuestr...

Effects of thymoquinone against cisplatin-induced cardiac injury in rats

Acta cir. bras; 31 (4), 2016
PURPOSE: T o investigate the possible protective effect of thymoquinone (TQ) in cisplatin (CP) induced myocardial injury. METHODS: A total of 28 adult male Wistar-Albino rats were randomly and equally divided into four groups as follows: Group 1 (control), Group 2 (CP at 15 mg/kg dose), Group 3 (TQ 40 ...