Mais um ministério de farda: coronavírus e militarismo, a dupla carga epidêmica sobre a Saúde
Physis (Rio J.); 30 (4), 2020
Results: 4434
A psicologia escolar e educacional em tempos de pandemia
Psicol. esc. educ; 24 (), 2020
Identification of SARS-CoV-2 and additional respiratory pathogens cases under the investigation of COVID-19 initial phase in a Brazilian reference laboratory
Mem. Inst. Oswaldo Cruz; 115 (), 2020
Coronavirus disease 2019 (COVID-19) surveillance, in Brazil, initiated shortly after its description, in China. Our aim was to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and additional pathogens in samples from the initial phase of the outbreak in Brazil, from late February to la...
Betacoronavirus/aislamiento & purificación, Brasil/epidemiología, COVID-19, China, Infecciones por Coronavirus/diagnóstico, Infecciones por Coronavirus/epidemiología, Diagnóstico Diferencial, Subtipo H1N1 del Virus de la Influenza A/aislamiento & purificación, Pandemias, Neumonía Viral/diagnóstico, Neumonía Viral/epidemiología, Rhinovirus/aislamiento & purificación, SARS-CoV-2
Preliminary results of SARS-CoV-2 detection in sewerage system in Niterói municipality, Rio de Janeiro, Brazil
Mem. Inst. Oswaldo Cruz; 115 (), 2020
This study presents preliminary results from a sewage-based surveillance to monitor the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the municipality of Niterói, State of Rio de Janeiro, Brazil. By using ultracentrifugation method associated to quantitative reverse transcrip...
Flavonoid glycosides and their putative human metabolites as potential inhibitors of the SARS-CoV-2 main protease (Mpro) and RNA-dependent RNA polymerase (RdRp)
Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Since the World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) to be a pandemic infection, important severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural proteins (nsp) have been analysed as promising targets in virtual screening approaches. Amon...
Betacoronavirus/efectos de los fármacos, COVID-19, Proteasas 3C de Coronavirus, Infecciones por Coronavirus, Cisteína Endopeptidasas, Flavonoides/farmacología, Glicósidos/farmacología, Simulación del Acoplamiento Molecular, Pandemias, Neumonía Viral, ARN Polimerasa Dependiente del ARN/antagonistas & inhibidores, SARS-CoV-2, Proteínas no Estructurales Virales/antagonistas & inhibidores
Pyomelanin biosynthetic pathway in pigment-producer strains from the pandemic Acinetobacter baumannii IC-5
Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Acinetobacter baumannii outbreaks have been associated with pandemic International Clones (ICs), but the virulence factors involved with their pathogenicity are sparsely understood. Pigment production has been linked with bacterial pathogenicity, however, this phenotype is rarely observed in A...
Infecciones por Acinetobacter/microbiología, Acinetobacter baumannii/efectos de los fármacos, Acinetobacter baumannii/genética, Acinetobacter baumannii/aislamiento & purificación, Antibacterianos/farmacología, Vías Biosintéticas/genética, Electroforesis en Gel de Campo Pulsado, Melaninas, Pruebas de Sensibilidad Microbiana, Tipificación de Secuencias Multilocus, Pandemias, beta-Lactamasas
Low risk of serological cross-reactivity between dengue and COVID-19
Mem. Inst. Oswaldo Cruz; 115 (), 2020
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential sero...
Anticuerpos Antivirales/inmunología, Betacoronavirus/inmunología, COVID-19, Infecciones por Coronavirus/inmunología, Reacciones Cruzadas, Dengue/inmunología, Virus del Dengue/inmunología, Ensayo de Inmunoadsorción Enzimática, Inmunoglobulina G/inmunología, Inmunoglobulina M/inmunología, Pandemias, Neumonía Viral/inmunología, SARS-CoV-2
Tracking the onset date of the community spread of SARS-CoV-2 in western countries
Mem. Inst. Oswaldo Cruz; 115 (), 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the world during 2020, but the precise time in which the virus began to spread locally is difficult to trace for most countries. Here, we estimate the probable onset date of the community spread of SARS-CoV-2 for heavily a...
Américas/epidemiología, Betacoronavirus, COVID-19, Infecciones Comunitarias Adquiridas/epidemiología, Infecciones Comunitarias Adquiridas/transmisión, Infecciones Comunitarias Adquiridas/virología, Infecciones por Coronavirus/epidemiología, Infecciones por Coronavirus/transmisión, Europa (Continente)/epidemiología, Pandemias, Neumonía Viral/epidemiología, Neumonía Viral/transmisión, SARS-CoV-2
COVID-19: molecular targets, drug repurposing and new avenues for drug discovery
Mem. Inst. Oswaldo Cruz; 115 (), 2020
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well ...
Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil
Mem. Inst. Oswaldo Cruz; 115 (), 2020
A new coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] is currently causing a life-threatening pandemic. In this study, we report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas, Brazil, and the protocol we designed to gen...