Results: 732

Skin disorders in renal transplant recipients: a retrospective study

An. bras. dermatol; 92 (5), 2017
Abstract: Background: Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic. Objectives: To identify the most frequent skin diseases and their clinical and demographical ...

Primary cutaneous amelanotic melanoma and gastrointestinal stromal tumor in synchronous evolution

An. bras. dermatol; 92 (5), 2017
Abstract: Gastrointestinal stromal tumor is rare digestive tract mesenchymal tumor, most often in the wall of the stomach. It is a benign neoplasm, but it can become malignant if not treated. We report a case of gastrointestinal stromal tumor that was discovered after abdominal ultrasonography during sta...

Pigmented Bowen's disease associated with high-risk HPV simulating melanoma of the hand

An. bras. dermatol; 92 (5), 2017
Abstract: Bowen's disease is an in situ squamous cell carcinoma of the skin with only 2% of pigmented cases reported. It is clinically characterized by papules and plaques of blackened surface that may be caused either by sun damage - usually in photoexposed areas in elderly individuals - or by human pap...

Primary cutaneous follicle center lymphoma

An. bras. dermatol; 92 (5), 2017
Abstract: Cutaneous lymphomas are classified according to their cellular origin into T-cell lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000 population. We report a case of a 56-year-old male patient who presented with a two-month history of nodules of varying sizes, some ulcera...

Comparação entre a associação de cobimetinibe e vemurafenibe e outras opções terapêuticas para o tratamento de melanoma metastático com mutação BRAFV600: número necessário para tratar (NNT)

Objetivo: O objetivo do estudo foi estimar e comparar o número necessário para tratar (NNT) entre a associação de cobimetinibe + vemurafenibe e outras opções terapêuticas no tratamento de melanoma metastático BRAFV600 mutado em primeira linha. Métodos: O NNT foi calculado como o inverso do risco...

Molecular basis of basal cell carcinoma

An. bras. dermatol; 92 (4), 2017
Abstract: Basal cell carcinoma is the most common cancer, presenting low mortality but high morbidity, and it has as risk factor exposure to sunlight, especially UVB spectrum. The most important constitutional risk factors for basal cell carcinoma development are clear phototypes (I and II, Fitzpatrick c...

Study of factors affecting the incidence of skin cancer in patients after liver transplant

An. bras. dermatol; 92 (4), 2017
Abstract: Background: Many factors are currently being identified as potential inductors of skin cancer in patients after a liver transplant, among them, immunosuppressive regimen. Objective: To study the factors that influence the incidence of skin cancer in patients after liver transplant. Methods: ...

Multiple vulvar dilated pores in a postmenopausal woman

An. bras. dermatol; 92 (4), 2017
Abstract: Winer's dilated pore is an infrequent appendageal tumor characterized by a giant comedone on the face, neck, and upper trunk in adults. We report a 57-year-old woman who developed multiple asymptomatic black papules on both labia majora. Histopathology showed grouped dilated follicles lined by ...

The recurrent nevus phenomenon

An. bras. dermatol; 92 (4), 2017
Abstract: Recurrent melanocytic nevus is a proliferation of melanocytes arising from a melanocytic nevus removed partially. Asymmetry and irregular pigmentation may lead to misdiagnosis of melanoma. We report a patient presented with a lesion on the lower abdomen, which was removed by shave excision. Ana...

Synchronous conjunctival melanoma and lentigo maligna melanoma

An. bras. dermatol; 92 (4), 2017
Abstract: Lentigo maligna has an extensive and neoplastic character. It typically progresses slowly and may eventually develop into an invasive melanoma, which is called lentigo maligna melanoma. Ocular melanoma is the second most common type of melanoma. The uvea is the most common site of origin of ocu...