ABSTRACT Background - Human epidermal growth factor receptor 2 (EGFR2/HER2/ErbB2) is a transmembrane receptor that stimulates cell proliferation when activated. The correlation of HER2 expression with prognosis has been studied in many cancer types. However, its relationship with survival of patients ...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Biomarcadores de Tumor/sangre,
Supervivencia sin Enfermedad,
Inmunohistoquímica,
Persona de Mediana Edad,
Pronóstico,
Receptor ErbB-2/sangre,
Receptor ErbB-2/metabolismo,
Estudios Retrospectivos,
Neoplasias Gástricas/sangre,
Neoplasias Gástricas/tratamiento farmacológico,
Neoplasias Gástricas/patología,
Resultado del Tratamiento
ABSTRACT We retrospectively evaluated the records of 49 grade 4 and 5 patients with 42 intracranial aneurysms treated within 72 h of subarachnoid hemorrhage (SAH). In total, 35 patients (71%) were grade 4, and 14 (29%) were grade 5. A total of 42 (85%) patients had one aneurysm, 6 (12%) had two aneurysms...
Abstract Aim The aim of this study was to compare both the efficacy and safety profile of the WHO-recommended, dual therapy (doxycycline–rifampin) to a quinolone-based, triple therapy (doxycycline–rifampin–levofloxacin) for treating acute/subacute brucellosis. Patients and methods We ...
ABSTRACT INTRODUCTION: The difficulty in choosing the appropriate therapy for chronic tinnitus relates to the variable impact on the quality of life of affected patients and, thus, requires individualization of treatment. OBJECTIVE: To evaluate the effectiveness of using sound generators with individ...
ABSTRACT INTRODUCTION: Nasal packing is routinely used in septal surgery to prevent postoperative bleeding. OBJECTIVE: To demonstrate the possibility of transeptal suture as a safe and effective way to avoid nasal packing and to improve efficiency. METHODS: This is a prospective, descriptive, infer...
Análisis Costo-Beneficio,
Epistaxis,
Tabique Nasal/cirugía,
Procedimientos Quirúrgicos Otorrinolaringológicos/economía,
Procedimientos Quirúrgicos Otorrinolaringológicos/métodos,
Dimensión del Dolor,
Cuidados Posoperatorios/métodos,
Hemorragia Posoperatoria/prevención & control,
Estudios Prospectivos,
Técnicas de Sutura,
Tampones Quirúrgicos,
Resultado del Tratamiento
ABSTRACT INTRODUCTION: Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this sym...
Antioxidantes/uso terapéutico,
Ácido Ascórbico/uso terapéutico,
Método Doble Ciego,
Ginkgo biloba/química,
Pérdida Auditiva Sensorineural/complicaciones,
Papaverina/uso terapéutico,
Fitoterapia/métodos,
Extractos Vegetales/uso terapéutico,
Estudios Prospectivos,
Índice de Severidad de la Enfermedad,
Factores Socioeconómicos,
Ácido Tióctico/uso terapéutico,
Acúfeno/complicaciones,
Acúfeno/tratamiento farmacológico,
Resultado del Tratamiento,
Vitamina E/uso terapéutico
ABSTRACT INTRODUCTION: Transcanal myringoplasty has the advantages of demanding lower operative time and minimal external incisions. It can be performed using the microscopic or endoscopic approach. In the last decade, the use of endoscopes in ear surgery has increased significantly. This technique may...
Estudios de Cohortes,
Estudios Transversales,
Conducto Auditivo Externo/cirugía,
Endoscopía/métodos,
Hospitales Universitarios,
Microcirugia/métodos,
Procedimientos Quirúrgicos Mínimamente Invasivos/métodos,
Miringoplastia/métodos,
Procedimientos Quirúrgicos Otológicos/métodos,
Resultado del Tratamiento,
Perforación de la Membrana Timpánica/cirugía
ABSTRACT INTRODUCTION: Local progression of papillary thyroid carcinoma (PTC) after failure of standard therapies may cause pain, ulceration, and bleeding. As patients are fully aware of the tumor growth, they might suffer high grade anxiety. Electrochemotherapy (ECT) is a new local palliative treatmen...
ABSTRACT INTRODUCTION: Aspirin-exacerbated respiratory disease (AERD) consists of a classic tetrad: moderate/severe asthma, chronic rhinosinusitis, nasal polyps, and intolerance to aspirin or other nonsteroidal anti-inflammatory drugs. Clinical control with drugs, surgery, and desensitization are treat...
Antiinflamatorios no Esteroideos/administración & dosificación,
Antiinflamatorios no Esteroideos/efectos adversos,
Antiinflamatorios no Esteroideos/inmunología,
Aspirina/administración & dosificación,
Aspirina/efectos adversos,
Aspirina/inmunología,
Asma Inducida por Aspirina/inmunología,
Asma Inducida por Aspirina/terapia,
Enfermedad Crónica,
Desensibilización Inmunológica,
Pólipos Nasales/inducido químicamente,
Pólipos Nasales/inmunología,
Pólipos Nasales/terapia,
Rinitis/inducido químicamente,
Rinitis/inmunología,
Rinitis/terapia,
Sinusitis/inducido químicamente,
Sinusitis/inmunología,
Sinusitis/terapia,
Resultado del Tratamiento
ABSTRACT INTRODUCTION: Sudden deafness is characterized by an abrupt hearing loss of at least 30 dB in three sequential frequencies in the standard pure tone audiogram over three days or less. Treatment is based on its etiology, and oral corticosteroids are widely used. Intratympanic corticosteroids ar...
