ABSTRACT Purpose To investigate the protective effects against ischemia reperfusion injury of dipyridamole in a model of induced priapism in rats. Materials and Methods Twenty-four male Sprague-Dawley rats were divided into four groups, control, P/R, P/R+DMSO and P/R+D. 3ml blood specimens were colle...
Antioxidantes/análisis,
Dipiridamol/farmacología,
Modelos Animales de Enfermedad,
Isquemia/prevención & control,
Precondicionamiento Isquémico/métodos,
Malondialdehído/sangre,
Oxidantes/sangre,
Estrés Oxidativo,
Erección Peniana/efectos de los fármacos,
Pene/irrigación sanguínea,
Pene/patología,
Priapismo/patología,
Priapismo/prevención & control,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Daño por Reperfusión/prevención & control,
Reproducibilidad de los Resultados,
Albúmina Sérica,
Albúmina Sérica Humana,
Factores de Tiempo,
Resultado del Tratamiento,
Vasodilatadores/farmacología,
Biomarcadores/sangre
ABSTRACT Purpose Mean platelet volume (MPV) is used to measure platelet size and is defined as a potential marker of platelet reactivity. Higher MPV levels have been defined as a risk factor for increased incidence of intravascular thrombosis and its associated diseases. We aimed to determine whether a...
Biomarcadores/sangre,
Recuento de Células Sanguíneas,
Análisis de los Gases de la Sangre,
Plaquetas/fisiología,
Estudios de Casos y Controles,
Isquemia/sangre,
Isquemia/etiología,
Isquemia/fisiopatología,
Volúmen Plaquetario Medio,
Persona de Mediana Edad,
Priapismo/sangre,
Priapismo/etiología,
Priapismo/fisiopatología,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Estadísticas no Paramétricas
The prevalence of Celiac disease in the general population is approximately 1% and remains undiagnosed in a significant proportion of individuals. Its clinical presentation includes the classical malabsorption syndrome, unspecific and extra-intestinal manifestations, and silent celiac disease. The serolo...
Autoanticuerpos/sangre,
Enfermedad Celíaca/sangre,
Enfermedad Celíaca/diagnóstico,
Enfermedad Celíaca/etiología,
Enfermedad Celíaca/terapia,
Inmunoglobulinas/sangre,
Transglutaminasas/sangre,
Biomarcadores/sangre,
Biopsia,
Inmunoglobulinas/inmunología,
Sensibilidad y Especificidad,
Transglutaminasas/inmunología
PURPOSE: Cardiopulmonary bypass (CPB) procedures are thought to activate systemic inflammatory reaction syndrome (SIRS). Strategies to curb systemic inflammation have been previously described. However, none of them is adequate, since "curbing" the extent of the inflammatory response requires a multimod...
PURPOSE : This study aimed to determine Cu/Zn ratio, nutritional and inflammatory status in patients during the perioperative period for colorectal cancer. METHODS: The study included patients with histological diagnosis of colorectal adenocarcinoma (Cancer Group, n=46) and healthy volunteers (Control G...
Adenocarcinoma/sangre,
Neoplasias Colorrectales/sangre,
Cobre/sangre,
Estado Nutricional,
Periodo Perioperatorio,
Zinc/sangre,
Biomarcadores/sangre,
Composición Corporal,
Índice de Masa Corporal,
Estudios de Casos y Controles,
Ingestión de Alimentos,
Ensayo de Inmunoadsorción Enzimática,
Inflamación/sangre,
Complejo de Antígeno L1 de Leucocito/sangre,
Desnutrición,
Valores de Referencia,
Factores de Riesgo,
Estadísticas no Paramétricas
Vaspin is a novel adipocytokine associated with glucose tolerance and chronic inflammation. Some studies reveal that vaspin may be involved in cardiovascular diseases. Our objective was to investigate the relationship between serum vaspin levels and endothelial function in patients with ankylosing spondy...
Análisis de Varianza,
Biomarcadores/sangre,
Glucemia/análisis,
Arteria Braquial/diagnóstico por imagen,
Arteria Braquial/patología,
Estudios de Casos y Controles,
Colesterol/sangre,
Endotelio Vascular/fisiopatología,
Resistencia a la Insulina,
Modelos Lineales,
Valores de Referencia,
Factores de Riesgo,
Serpinas/sangre,
Espondilitis Anquilosante/sangre,
Espondilitis Anquilosante/fisiopatología,
Triglicéridos/sangre
T lymphocytes are important in the pathogenesis of psoriasis, and increasing evidence indicates that B cells also play an important role. The mechanisms of action, however, remain unclear. We evaluated the ratios of CD19+ B cells in peripheral blood mononuclear cells (PBMCs) from 157 patients with psoria...
Abstract Potentially malignant disorders (PMDs) of oral cavity and oral cancer remain a cause of serious concern despite intensive research and development. Diet and immunity have been identified to play a crucial role as modifying factors in these diseases. Our study intended to explore this relationshi...
Distribución por Edad,
Análisis de Varianza,
Complejo Antígeno-Anticuerpo/sangre,
Biomarcadores/sangre,
Carcinoma de Células Escamosas/sangre,
Estudios de Casos y Controles,
Cobre/sangre,
Diagnóstico Precoz,
Hierro/sangre,
Liquen Plano Oral/sangre,
Persona de Mediana Edad,
Neoplasias de la Boca/sangre,
Fibrosis de la Submucosa Bucal/sangre,
Lesiones Precancerosas/sangre,
Valores de Referencia,
Factores de Riesgo,
Distribución por Sexo
Abstract The main objective of this study was to cause bisphosphonate-related osteonecrosis of the jaws to develop in a rodent model. Adult male Holtzman rats were assigned to one of two experimental groups to receive alendronate (AL; 1 mg/kg/week; n = 6) or saline solution (CTL; n = 6). After 60 days of...
Alendronato/administración & dosificación,
Fosfatasa Alcalina/sangre,
Biomarcadores/sangre,
Osteonecrosis de los Maxilares Asociada a Difosfonatos/diagnóstico por imagen,
Osteonecrosis de los Maxilares Asociada a Difosfonatos/etiología,
Densidad Ósea/efectos de los fármacos,
Conservadores de la Densidad Ósea/administración & dosificación,
Colágeno Tipo I/sangre,
Modelos Animales de Enfermedad,
Ensayo de Inmunoadsorción Enzimática,
Péptidos/sangre,
Ratas Sprague-Dawley,
Factores de Tiempo,
Extracción Dental,
Alveolo Dental/efectos de los fármacos,
Alveolo Dental/patología
Introdução: O tecido adiposo é um importante órgão endócrino secretor de adipocinas como a interleucina-6 (IL-6), que estimula a produção de proteínas de fase aguda no fígado, conduzindo a um estado inflamatório subclínico associado ao surgimento de comorbidades presentes na obesidade, como a...
