Abstract In recent years, natural products with antifungal and antioxidant activities are being increasingly researched for a more sustainable alternative to the chemicals currently used for the same purpose. The plant pathogenic fungus Alternaria alternata is a causative agent of diseases in citrus, le...
The aim of this study was to evaluate the effects of single oral doses of D-005 (a lipid extract obtained from the fruit oil of Acrocomia crispa) on LPS-induced acute lung injury (ALI) in mice. D-005 batch composition was: lauric (35.8%), oleic (28.4%), myristic (14.2%), palmitic (8.9%), stearic (3.3%), ...
Arecaceae,
Extractos Vegetales/administración & dosificación,
Ácidos Grasos/análisis,
Lipopolisacáridos/efectos adversos,
Lesión Pulmonar Aguda/prevención & control,
Lesión Pulmonar Aguda/inducido químicamente,
Cromatografía de Gases,
Administración Oral,
Extractos Vegetales/química,
Frutas,
Pulmón/efectos de los fármacos
Mammadov, Renad;
Suleyman, Bahadir;
Altuner, Durdu;
Demirci, Elif;
Cetin, Nihal;
Yilmaz, Adnan;
Baykal, Huseyin;
Alpcan, Hilal;
Turumtay, Emine Akyuz;
Suleyman, Halis.
Abstract Purpose: To investigate the effects of the EtOAc extract of U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: The anticancer activity of EtOAc extract of U. longissima was examined in the esopha...
Abstract Purpose: To evaluate the healing potential of the Ximenia americana hydroalcoholic extract in 10% cream in excisional wound models in rats. Methods: Sixty male adults Wistar rats were submitted to skin and subcutaneous tissue surgery in the right and left thoracic regions, divided into three...
Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biomarcadores/sangre,
Hepatectomía/métodos,
Hepatocitos/efectos de los fármacos,
Hiperplasia/tratamiento farmacológico,
Hígado/efectos de los fármacos,
Hígado/patología,
Hígado/cirugía,
Extractos Vegetales/administración & dosificación,
Plectranthus/química
Abstract Purpose To investigate the effects of pine needle extract (PNE) on the expression of proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by 70% partial hepatectomy (PH) in rat. Methods Forty-eight male rats (SD, 7 weeks) had surgery (70% PH). They were randoml...
Proliferación Celular,
Hepatectomía/métodos,
Antígeno Ki-67/efectos adversos,
Antígeno Ki-67/metabolismo,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Pinus/química,
Extractos Vegetales/farmacología,
Antígeno Nuclear de Célula en Proliferación/efectos de los fármacos,
Antígeno Nuclear de Célula en Proliferación/metabolismo,
Ratas Sprague-Dawley,
Factores de Tiempo
Abstract Objective: This study aimed to evaluate the effect of avocado/soybean unsaponifiables (ASU) on periodontal repair in rats with induced periodontitis and arthritis. Methodology: Forty-five rats were submitted to periodontitis induction by insertion of ligatures into the upper second molars, mai...
Artritis/tratamiento farmacológico,
Artritis/patología,
Inmunohistoquímica,
Periodontitis/tratamiento farmacológico,
Periodontitis/patología,
Persea/química,
Extractos Vegetales/farmacología,
Ligando RANK/análisis,
Distribución Aleatoria,
Reproducibilidad de los Resultados,
Glycine max/química,
Fosfatasa Ácida Tartratorresistente/análisis,
Factores de Tiempo,
Resultado del Tratamiento,
Microtomografía por Rayos X
En los últimos años, la investigación de productos naturales ha atraído mucha atención en todo el mundo. Las plantas medicinales se han utilizado desde la antigüedad y constituyen una importante fuente de nuevos medicamentos. El objetivo de este trabajo de Tesis Doctoral fue avanzar en el diseño d...
Medicina Tradicional,
Plantas Medicinales,
Fitoterapia,
Candida,
Fitoquímicos,
Argentina,
Antiinflamatorios,
Antioxidantes,
Flavonoides,
Antifúngicos,
Extractos Vegetales,
Micosis
Cuscuta chinensis Lam. (Convolvulaceae) is an important herbal medicine widely used to improve sexual function, treat osteoporosis, and prevent aging, and has been reported to exhibit anti-osteoporotic effects in vitro. However, the activity of Cuscuta chinensis Lam. on glucocorticoid-induced osteoporosi...
Western Blotting,
Densidad Ósea/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Cuscuta/química,
Dexametasona/farmacología,
Glucocorticoides/farmacología,
Inmunohistoquímica,
Osteoporosis/inducido químicamente,
Osteoporosis/prevención & control,
Osteoprotegerina/efectos de los fármacos,
Osteoprotegerina/metabolismo,
Extractos Vegetales/farmacología,
Ligando RANK/efectos de los fármacos,
Ligando RANK/metabolismo,
ARN Mensajero,
Ratas Sprague-Dawley
Alves, N T Q;
Ximenes, R M;
Jorge, R J B;
Silveira, J A M;
Santos, J V A;
Rodrigues, F A P;
Costa, P H S;
Xavier Jr, F A F;
Evangelista, J S A M;
Havt, A;
Soares, V C G;
Toyama, M H;
Oliveira, A N A;
Araújo, R M;
Alves, R S;
Monteiro, H S A.
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararac...
Antivenenos/aislamiento & purificación,
Antivenenos/farmacología,
Bothrops,
Venenos de Crotálidos/antagonistas & inhibidores,
Venenos de Crotálidos/toxicidad,
Modelos Animales de Enfermedad,
Relación Dosis-Respuesta a Droga,
Edema/tratamiento farmacológico,
Edema/etiología,
Hemorragia/tratamiento farmacológico,
Hemorragia/etiología,
Extractos Vegetales/farmacología,
Raíces de Plantas/química,
Polygalaceae/química
