ABSTRACT In this paper, the existence of a genotype x environment interaction for the average daily weight in GIFT Nile tilapia (Oreochromis niloticus) in different regions in the state of Paraná (Brazil) was analyzed. The heritability results were high in the uni-characteristic analysis: 0.71, 0.72 and...
ABSTRACT Objective To evaluate the frequency of DQ2.5 and DQ8 alleles using the Tag-single-nucleotide polymorphism (Tag-SNP) technique in individuals with type 1 diabetes mellitus (T1DM) and celiac disease (CD) in southern Brazil. Materials and methods In a prospective design, we performed the search...
Enfermedad Celíaca/complicaciones,
Enfermedad Celíaca/genética,
Diabetes Mellitus Tipo 1/complicaciones,
Diabetes Mellitus Tipo 1/genética,
Frecuencia de los Genes/genética,
Predisposición Genética a la Enfermedad/genética,
Genotipo,
Cadenas alfa de HLA-DQ/genética,
Cadenas beta de HLA-DQ/genética,
Polimorfismo de Nucleótido Simple,
Estudios Prospectivos,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Factores de Riesgo
SUMMARY Identification of the correct etiology of diabetes brings important implications for clinical management. In this report, we describe a case of a 4-year old asymptomatic girl with diabetes since age 2, along with several individuals in her family with different etiologies for hyperglycemia identi...
Diabetes Mellitus/clasificación,
Diabetes Mellitus/genética,
Predisposición Genética a la Enfermedad,
Pruebas Genéticas,
Genotipo,
Quinasas del Centro Germinal,
Factor Nuclear 1-alfa del Hepatocito/genética,
Factor Nuclear 4 del Hepatocito/genética,
Mutación,
Linaje,
Proteínas Serina-Treonina Quinasas/genética
Abstract Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306,...
Broncodilatadores/uso terapéutico,
Estudios Transversales,
Fibrosis Quística/tratamiento farmacológico,
Fibrosis Quística/genética,
Regulador de Conductancia de Transmembrana de Fibrosis Quística/genética,
Genotipo,
Interleucina-8/efectos de los fármacos,
Interleucina-8/genética,
Mutación,
Reacción en Cadena de la Polimerasa,
Polimorfismo de Longitud del Fragmento de Restricción,
Índice de Severidad de la Enfermedad,
Espirometría
BACKGROUND Acanthamoeba is the genus of free-living amoebae that is most frequently isolated in nature. To date, 20 Acanthamoeba genotypes have been described. Genotype T4 is responsible for approximately 90% of encephalitis and keratitis cases. Due to the ubiquitous presence of amoebae, isolation from e...
BACKGROUND The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local popu...
Resumen Introducción: La infección por VPH es la infección viral de transmisión sexual más frecuente, y se encuentra asociada a diversas neoplasias. Objetivo: Describir la epidemiología, historia natural y factores de riesgo asociados a la infección oral por VPH en adultos jóvenes asintomático...
Boca/virología,
Infecciones por Papillomavirus/epidemiología,
Infecciones por Papillomavirus/transmisión,
Enfermedades Virales de Transmisión Sexual/epidemiología,
Enfermedades Virales de Transmisión Sexual/transmisión,
Genotipo,
Conductas de Riesgo para la Salud,
México/epidemiología,
Papillomaviridae/aislamiento & purificación,
Reacción en Cadena de la Polimerasa,
Prevalencia,
Estudios Prospectivos,
Factores de Riesgo,
Factores Sexuales,
Conducta Sexual
Summary Objective: To explore the correlation between growth differentiation factor 15 (GDF-15) -3148C/G polymorphism and the formation of collateral circulation in acute ST-elevation myocardial infarction (STEMI) in Han population of Taiyuan area. Method: The present study included 92 STEMI patients a...
Estudios de Casos y Controles,
Circulación Colateral/fisiología,
Angiografía Coronaria,
Frecuencia de los Genes,
Genotipo,
Factor 15 de Diferenciación de Crecimiento/genética,
Persona de Mediana Edad,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Factores de Riesgo,
Infarto del Miocardio con Elevación del ST/diagnóstico por imagen,
Infarto del Miocardio con Elevación del ST/genética
Background: Availability of related rice species is critical for rice breeding and improvement. Two distinct species of domesticated rice exist in the genus Oryza: Oryza sativa (Asian rice) and Oryza glaberrima (African rice). New rice for Africa (NERICA) is derived from interspecific crosses between the...
A recent study showed that infectivity of Zika virus (ZIKV) Asian genotype was enhanced by an alanine-to-valine amino acid substitution at residue 188 of the NS1 protein, but the precise time and location of origin of this mutation were not formally estimated. Here, we applied a Bayesian coalescent-based...
