Abstract In China, Scutellaria is used for treating inflammatory-related diseases. Baicalin is the main active component of Scutellaria and has protective effects on acute pancreatitis. However, the mechanism of Baicalin is still unclear. In this study, the protective effects of baicalin on acute pancrea...
Abstract Whole-body bone scintigraphy (WB-BS) is used for detecting and monitoring metastatic spread of prostate cancer (PCa) and to investigate bone pain episodes. To investigate the impact of a positive WB-BS on pain-relieving medicine prescription in PCa patients, a single-center, retrospective cohort...
Braga, Tatiane Vieira;
Evangelista, Fernanda Cristina Gontijo;
Santiago, Marie Gabriele;
Ferrão, Aline Lúcia Menezes;
Almeida, Tamara Dauare de;
Barbosa, Bárbara Lima da Fonseca;
Araujo, Sergio Schusterschitz da Silva;
Ribeiro, Glaciano Nogueira;
Carvalho, Maria das Graças;
Sabino, Adriano de Paula.
Chronic lymphocytic leukemia (CLL) is a blood cancer characterized by the accumulation of clonal B-lymphocytes. This study evaluated the mRNA gene expression of miR-15a, miR-16- 1, ZAP-70, and Ang-2 by qPCR, as well as the plasma levels of Bcl-2 by Elisa immunoassay, in CLL patients and healthy controls....
Abstract The main aim of the study is to quantify the cytotoxic property of the Fucoidan extracted from the Turbinaria conoides using the MTT assay with the standard fucose. Fucoidan was extracted using the soaked water method and it was determined using the HPLC procedure the obtained Test sample Fucoid...
Técnicas In Vitro/instrumentación,
Células MCF-7,
Células A549,
Citotoxinas/efectos adversos,
Cromatografía Líquida de Alta Presión/métodos,
Concentración 50 Inhibidora,
Fibroblastos/clasificación,
Fucosa/análogos & derivados,
Línea Celular,
Neoplasias Pulmonares/patología,
Neoplasias de la Mama/patología
Abstract Background and aim: Stingless bee propolis, a resinous compound processed by mandibular secretion of stingless bees, is used for maintenance of hygiene and stability of beehives. Research on stingless bee propolis shows therapeutic properties attributed to polyphenols exhibiting antioxidative, a...
Própolis/efectos adversos,
Abejas/clasificación,
Metformina/agonistas,
Antioxidantes/efectos adversos,
Cardiomiopatías Diabéticas/patología,
Eosina Amarillenta-(YS),
Cardiomegalia/patología,
Coloración y Etiquetado/instrumentación,
Glucemia/metabolismo,
Hipoglucemiantes,
Ingestión de Líquidos,
Ratas Sprague-Dawley/clasificación,
Ventrículos Cardíacos/anomalías
Abstract Design of experiment (DoE) is a useful time and cost-effective tool for analyzing the effect of independent variables on the formulation characteristics. The aim of this study is to evaluate the effect of the process variables on the characteristics involved in the preparation of Diclofenac Sodi...
Nanopartículas/análisis,
Optimización de Procesos,
Análisis de Fourier,
Costos y Análisis de Costo/métodos,
Diclofenaco/análisis,
Espectroscopía Infrarroja por Transformada de Fourier,
Metodología como un Tema,
Microscopía Electrónica de Rastreo/métodos,
Preparaciones Farmacéuticas,
Técnicas In Vitro/instrumentación,
Rastreo Diferencial de Calorimetría/instrumentación
Abstract The main purposes of the current study were to formulate o/w nanoemulsions as a carrier for Tamarindus indica (tamarind) fruit pulp extract and to study the antioxidant and antibacterial potentials of nanoemulsions containing tamarind extract, focusing on cosmetic/hygiene applications. The o/w n...
Abstract The hospital pharmacy needs a constant process of evaluation and monitoring of its activities. In Brazil, several agencies establish tasks and duties for pharmacists, but little is known about the compliance and the perception of the professional regarding these policies. The present study aims ...
Abstract The study is aimed at investigating the functional physicochemical and solid state characteristics of food-grade Tetracarpidium conophorum (T. conophorum) oil for possible application in the pharmaceutical industry for drug delivery. The oil was obtained by cold hexane extraction and its physico...
Abstract Neonatal sepsis continues to be a major cause of morbidity and mortality worldwide. Coagulase-negative staphylococci (CoNS), commonly found on the skin, being the main agents isolated. The aim of this study was to evaluate CoNS isolated from blood cultures of newborn (NB) infants. The study took...
Recién Nacido,
Síndrome Estafilocócico de la Piel Escaldada/patología,
Coagulasa/efectos adversos,
Cultivo de Sangre/instrumentación,
Staphylococcus epidermidis/patogenicidad,
Cultivo de Sangre/clasificación,
Sepsis/patología,
Pruebas de Sensibilidad Microbiana/instrumentación,
Mortalidad,
Hospitales,
Piel
