SUMMARY: Brassica juncea (Indian mustard) seeds are consumed in treatment of high blood pressure, headache and prevention of heart disease. The aim of the present study was to investigate the effects of methanol extract of Brassica juncea seeds [BJME] on the heart and liver of adult Albino Wistar rats. A...
Planta de la Mostaza/química,
Extractos Vegetales/farmacología,
Corazón/efectos de los fármacos,
Hígado/efectos de los fármacos,
Semillas,
Extractos Vegetales/administración & dosificación,
Aspartato Aminotransferasas/análisis,
Alanina Transaminasa/análisis,
Fosfatasa Alcalina/análisis,
Ratas Wistar,
Metanol/farmacología,
Metanol/administración & dosificación,
Factores de Tiempo
SUMMARY: Origanum vulgare Linn has traditionally been used as a diuretic and antispasmodic. Therefore, we investigated the active extract of Origanum vulgare for possible andrological effect and preventive effects against testicular damage using ethylene glycol rat model of testicular damage, to rational...
RESUMEN: Estudios recientes han demostrado que los compuestos activos presentes en extractos de C. chayamansa, E. prostrata y J. dioica tienen propiedades antioxidantes. Los resultados obtenidos en nuestro estudio fueron compuestos fenólicos solubles mostraron en C. chayamansa 6,34, E. prostrata 10,67, ...
Jatropha/química,
Euphorbia/química,
Extractos Vegetales/administración & dosificación,
Hiperglucemia/tratamiento farmacológico,
Antioxidantes/administración & dosificación,
Fenoles/análisis,
Flavonoides/análisis,
Extractos Vegetales/química,
Antioxidantes/química,
Hígado/efectos de los fármacos,
Riñón/efectos de los fármacos,
Ratas Wistar,
Hiperglucemia/inducido químicamente,
Compuestos Fenólicos
ABSTRACT Objective: To investigate the anti-hyperglycemic effects of Plathymenia reticulata hydroalcoholic extract and related changes in body weight, lipid profile and the pancreas. Methods: Diabetes was induced in 75 adult male Wistar rats via oral gavage of 65mg/Kg of streptozotocin. Rats were alloc...
Glucemia/análisis,
Peso Corporal/efectos de los fármacos,
Colesterol,
Diabetes Mellitus Experimental/inducido químicamente,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Fabaceae,
Hiperplasia/patología,
Hipoglucemiantes/farmacología,
Fitoterapia,
Extractos Vegetales/farmacología,
Hojas de la Planta,
Ratas Wistar,
Estreptozocina
Abstract Phytochemical content of plant extracts can be used effectively to reduce the metal ions to nanoparticles in one-step green synthesis process. In this study, six plant extracts were used for the synthesis of silver nanoparticles (AgNPs). Biologically synthesized AgNPs was characterized using UV-...
Abstract Objective: To evaluate the effectiveness of gargling the solution of ant nest extract against plaque formation in children who experience Early Childhood Caries (ECC) when used as a mouthwash. Material and Methods: This study uses a pretest-posttest design with a control group. Thirty children...
This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa ...
Citocinas/sangre,
Modelos Animales de Enfermedad,
Microbioma Gastrointestinal/efectos de los fármacos,
Inflamación/prevención & control,
Lindera/química,
Lipopolisacáridos/sangre,
Hígado/ultraestructura,
Hepatopatías Alcohólicas/diagnóstico por imagen,
Hepatopatías Alcohólicas/prevención & control,
Extractos Vegetales/farmacología,
Raíces de Plantas/química,
Proteínas Serina-Treonina Quinasas/sangre,
Ratas Sprague-Dawley,
Receptor Toll-Like 4/sangre
Excessive pro-inflammatory cytokines result in adverse pregnancy outcomes, including preeclampsia-like phenotypes, and fetal growth restriction. Anti-inflammation might be an effective therapy. The aim of this research was to investigate whether Uncaria rhynchophylla alkaloid extract (URE), a highly safe...
Yu, Cheng Hao;
Zhao, Jin Shuang;
Zhao, Hui;
Peng, Teng;
Shen, Dong Cheng;
Xu, Qiu Xia;
Li, Yao;
Webb, R. Clinton;
Wang, Mong Heng;
Shi, Xing Ming;
Peng, Cheng;
Ding, Wei Jun.
The aim of this study was to elucidate the concise effects of a traditional herb pair, Curcumae rhizoma-Sparganii rhizoma (CRSR), on uterine leiomyoma (UL) by analyzing transcriptional profiling. The UL rat model was made by intramuscular injection of progesterone and gavage administration of diethylstil...
Curcuma/química,
Modelos Animales de Enfermedad,
Regulación Neoplásica de la Expresión Génica/efectos de los fármacos,
Leiomioma/tratamiento farmacológico,
Leiomioma/genética,
Leiomioma/metabolismo,
Análisis de Secuencia por Matrices de Oligonucleótidos,
Extractos Vegetales/farmacología,
Radioinmunoensayo,
Ratas Sprague-Dawley,
Rizoma/química,
Factores de Transcripción,
Neoplasias Uterinas/tratamiento farmacológico,
Neoplasias Uterinas/genética,
Neoplasias Uterinas/metabolismo
Silva, Diego Romário;
Rosalen, Pedro Luiz;
Freires, Irlan Almeida;
Sardi, Janaína de Cássia Orlandi;
Lima, Rennaly Freitas;
Lazarini, Josy Goldoni;
Costa, Tereza Karla Vieira Lopes da;
Pereira, Jozinete Vieira;
Godoy, Gustavo Pina;
Costa, Edja Maria Melo de Brito.
Abstract: We evaluated the antifungal and antibiofilm potential of the hydroalcoholic extract of bark from Anadenanthera colubrina (vell.) Brenan, known as Angico, against Candida spp. Antifungal activity was evaluated using the microdilution technique through the Minimum Inhibitory and Fungicide Concent...
Análisis de Varianza,
Antifúngicos/farmacología,
Biopelículas/efectos de los fármacos,
Candida/efectos de los fármacos,
Recuento de Colonia Microbiana,
Fabaceae/química,
Pruebas de Sensibilidad Microbiana,
Microscopía Electrónica de Rastreo,
Nistatina/farmacología,
Extractos Vegetales/farmacología,
Reproducibilidad de los Resultados,
Factores de Tiempo