Results: 3722

Moringa oleifera Plant as potent alternate to Chemical Coagulant in Water Purification

Abstract Quality of groundwater is threatened due to pollution by industrial, domestic and agricultural waste. A large number of populations are residing in rural areas which are unable to afford high cost water purifiers due to their low income as well as limited awareness. However, limited availability...

Development and validation of an LC-MS/MS method for pharmacokinetic study of lobetyolin in rats

Abstract A simple and selective liquid chromatography tandem with mass spectrometry (LC-MS/ MS) method for quantification of lobetyolin in rat plasma was developed and validated. Chromatographic separation was achieved on a Thermo ODS C18 reversed-phase column using 0.1% aqueous formic acid-methanol (50...

Synthesis and characterization of Sophora alopecuroides L. green synthesized of Ag nanoparticles for the antioxidant, antimicrobial and DNA damage prevention activity

Abstract In this study, it was aimed to investigate the amount of antioxidant, protective properties against DNA damage and antibacterial properties against various pathogens after the interaction of Ag metal (Ag NPs/Sa) of Sophora alopecuroides L. (S. alopecuroides L) plant seed, which is grown in Iğd...

Anti-proliferative effects of paroxetine alone or in combination with sorafenib in HepG2 cells

Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib is the first approved drug for the treatment of advanced HCC. Depression is frequent in cancer patients. Moreover, sorafenib might exert depression as an adverse drug reaction and paroxetine, a selective serotoni...

Development and optimization of metoclopramide containing polymeric patches: impact of permeation enhancers

Abstract The study is aimed to develop a monolithic controlled matrix transdermal patches containing Metoclopramide as a model drug by solvent casting method. Eudragit L100, Polyvinylpyrrolidone K-30, and Methylcellulose were used in different ratios and Polyethylene glycol 400 added as a plasticizer. Re...

Synergy in penicillin, cephalosporin, amphenicols, and aminoglycoside against MDR S. aureus isolated from Camel milk

Abstract This study investigated the synergy testing of penicillin, cephalosporin, amphenicols, and aminoglycoside in the camel milk (n=768 samples), subsequently used for isolation of MDR S. aureus targeting mecA gene. Antibiotic susceptibility of S. aureus showed >90% isolates were sensitive to ciprof...

Decreased body-fat accumulation and increased vasorelaxation to glyceryl trinitrate in middle-aged male rats following six-weeks consumption of coconut milk protein

Abstract We investigated whether coconut milk protein (CMP) contributes to the beneficial effects of coconut milk consumption on cardiovascular health markers previously found in middle-aged rats. CMP was isolated and precipitated from dried fresh coconut milk, then gavaged (1 g/kg) to middle-aged male r...

Produção de existências em ato na Amazônia, Brasil: "território líquido" que se mostra à pesquisa como travessia de fronteiras

O objetivo do artigo é compartilhar a aprendizagem em pesquisa, fruto da vivência das pesquisadoras e dos pesquisadores na rede de cuidado à saúde de urgência e emergência na Amazônia, Brasil. Propomos pensar no conceito de pesquisa como travessia de fronteiras para falar da interculturalidade, da...

Medos, desejos e preocupações acerca da sindemia de Covid-19 e sofrimento psíquico: experiências extensionistas no sul da Bahia, Brasil

Este artigo analisa as relações entre políticas públicas de enfrentamento da Covid-19, desinformação da população e sofrimento psíquico por meio da integração de resultados de duas experiências extensionistas ocorridas no mesmo território e mesmo período de tempo: "Tira dúvidas sobre a Cov...

Os itinerários terapêuticos de populações vulneráveis na Covid-19: uma revisão de escopo

Com o objetivo de investigar os Itinerários Terapêuticos percorridos pela população brasileira em situação de vulnerabilidade social na busca do cuidado em saúde durante a pandemia da Covid-19, foi realizada uma revisão de escopo de julho a novembro de 2021, conforme proposta de Joanna Briggs Ins...