Results: 467

Potenciales antimitóticos. 2. sintesis de 1-bencil-3-carboetoxi-2quinolonas
Antimitotic potentials. 2. Synthesis of 1-benzyl-3-carbethoxy-2-quinolones

Acta cient. venez; 53 (2), 2002
Un grupo de 1-bencil-3-carbethoxi-2-quinolonas sustituidas, diseñadas en base a las estructuras de antimitóticos bien establecidos, fueron sintetizados mediante una secuencia de tres reacciones. Aunque los rendimientos de la primera reacción (condensación de o-nitrobenzaldehídos sustituidos con malo...

Resistencia multidroga (MDR) o pleiotropica
Multidrug or pleiotropic resistance

Acta cient. venez; 51 (1), 2000
La resistencia que se genera a los agentes citotóxicos, es uno de los mayores obstáculos que se presenta en el tratamiento del cáncer, existiendo diversar causas para los fracasos terapúuticos, sidneo la principal una resistencia intrínseca de la célula tumoral. Así se ha determinado la presencia ...

The rebound effect in the treatment of complex hemangioma with interferon alpha 2A

Säo Paulo med. j; 116 (5), 1998
The authors report the case of an infant with an extensive face hemangiona with subglottic airway obstruction which had been successfully treated with interferon alpha 2A but then reoccurred with the same dimensions and airway blockage after treatment was abruptly interrupted. The authors suggest the imp...

Granulocytic sarcooma presented as a reactivation of chronic myeloid leukemia after allogenic marrow transplantation

Säo Paulo med. j; 116 (2), 1998
The authors report the case of a chronic myeloid leukemia (CML) patient submitted to allogenic bone marrow transplantation, who had probably never entered complete remission. The disease was reactivated as a granulocytic sarcoma, next to a platinum plate installed to correct a tibia fracture 11 years ear...

The relevance of crossmatch and HLA compatibility in liver transplantation

ABCD (São Paulo, Impr.); 12 (3/4), 1997
Encontra-se bem definido o papel dos aloanticorpos HLA no desencadeamento da rejeicao hiperaguda nos transplantes renais. Nos casos dos transplantes hepaticos, assim como nos transplantes cardiacos, permanece controverso o papel de anticorpos pre-formados na sobrevida do enxerto. Realizamos neste estudo ...

Criopreservaçäo de medula óssea e células pluripotentes periféricas utilizando um congelador programável: experiência em 86 congelamentos
Cryopreservation of bone marrow and peripheral blood stem cells using a controlled rate freezing system: experience on 86 procedures

A infusao de células hematopoéticas totipotentes criopreservadas permite a recuperaçao da hematopoese após quimioterapia mieolblativa. Objetivo. A formaçao de cristais de gelo durante o processo de congelamento é o fator principal que causa ruptura das estruturas celulares. A criopreservaçao dessa...

Tratamiento médico de 44 pacientes con carcinoma del conducto anal. Intergrupo Argentino para el Tratamiento de los Tumores Gastro-Intestinales (IATTGI)
[Medical treatment of 44 patients with anal canal carcinoma. Argentinian Intergroup for the treatment of gastrointestinal tumors (IATTGI)]

Medicina (B.Aires); 55 (3), 1995
In order to investigate the medical treatment of anal canal carcinoma (ACC), 27 patients (pts) were treated with cisplatin, fluorouracil and radiotherapy, in an alternating schedule. Eleven pts received mitomycin C, fluorouracil and radiotherapy, in a concurrent scheme. Finally, six pts were included in ...

Sesquiterpene lactones from Vernonia

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Some informations about the sesquiterpene lactones isolated from Brazilian species of Vernonia are described, as well the results of tests developed with such compounds with respect to their anti-feedant, molluscicide, antimicrobial and analgesic properties....