This study presents preliminary results from a sewage-based surveillance to monitor the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the municipality of Niterói, State of Rio de Janeiro, Brazil. By using ultracentrifugation method associated to quantitative reverse transcrip...
Darc, Mirela;
Cosentino, Matheus Calvano;
Moreira, Filipe Romero Rebello;
Cavalcante, Liliane Tavares Faria;
Augusto, Anderson Mendes;
Trocolli, Fernando;
Ubiali, Daniel Guimarães;
Verona, Carlos Eduardo;
Soares, Marcelo Alves;
Santos, André Felipe.
In an enclosure with nine collared peccaries (Pecari tajacu) from the Rio de Janeiro city Zoo, Brazil, one specimen was found dead and two others developed prostration, apathy and dehydration, resulting on its death. Necropsy of two animals pointed to pulmonary and renal damage. Histological examination ...
BACKGROUND Since the World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) to be a pandemic infection, important severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural proteins (nsp) have been analysed as promising targets in virtual screening approaches. Amon...
Betacoronavirus/efectos de los fármacos,
COVID-19,
Proteasas 3C de Coronavirus,
Infecciones por Coronavirus,
Cisteína Endopeptidasas,
Flavonoides/farmacología,
Glicósidos/farmacología,
Simulación del Acoplamiento Molecular,
Pandemias,
Neumonía Viral,
ARN Polimerasa Dependiente del ARN/antagonistas & inhibidores,
SARS-CoV-2,
Proteínas no Estructurales Virales/antagonistas & inhibidores
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential sero...
Anticuerpos Antivirales/inmunología,
Betacoronavirus/inmunología,
COVID-19,
Infecciones por Coronavirus/inmunología,
Reacciones Cruzadas,
Dengue/inmunología,
Virus del Dengue/inmunología,
Ensayo de Inmunoadsorción Enzimática,
Inmunoglobulina G/inmunología,
Inmunoglobulina M/inmunología,
Pandemias,
Neumonía Viral/inmunología,
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the world during 2020, but the precise time in which the virus began to spread locally is difficult to trace for most countries. Here, we estimate the probable onset date of the community spread of SARS-CoV-2 for heavily a...
Américas/epidemiología,
Betacoronavirus,
COVID-19,
Infecciones Comunitarias Adquiridas/epidemiología,
Infecciones Comunitarias Adquiridas/transmisión,
Infecciones Comunitarias Adquiridas/virología,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/transmisión,
Europa (Continente)/epidemiología,
Pandemias,
Neumonía Viral/epidemiología,
Neumonía Viral/transmisión,
SARS-CoV-2
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well ...
Nascimento, Valdinete Alves do;
Corado, André de Lima Guerra;
Nascimento, Fernanda Oliveira do;
Costa, Ágatha Kelly Araújo da;
Duarte, Debora Camila Gomes;
Luz, Sérgio Luiz Bessa;
Gonçalves, Luciana Mara Fé;
Jesus, Michele Silva de;
Costa, Cristiano Fernandes da;
Delatorre, Edson;
Naveca, Felipe Gomes.
A new coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] is currently causing a life-threatening pandemic. In this study, we report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas, Brazil, and the protocol we designed to gen...
Infecciones Asintomáticas,
Betacoronavirus/genética,
Brasil,
COVID-19,
Infecciones por Coronavirus/virología,
Genoma Viral,
Genómica,
Mutación,
Pandemias,
Filogenia,
Filogeografía,
Neumonía Viral/virología,
SARS-CoV-2,
España
Chagas, Aline Lopes;
da Fonseca, Leonardo Gomes;
Coelho, Fabricio Ferreira;
da Cunha Saud, Lisa Rodrigues;
Abadala, Edson;
Andraus, Wellington;
Fiore, Lucas;
Moreira, Airton Mota;
Menezes, Marcos Roberto;
Carnevale, Francisco César;
Tani, Claudia Megumi;
Alencar, Regiane S S M;
DAlbuquerque, Luiz Augusto Carneiro;
Herman, Paulo;
Carrilho, Flair José.
More than 18 million people in 188 countries have been diagnosed as having coronavirus disease (COVID-19), and COVID-19 has been responsible for more than 600,000 deaths worldwide. Brazil is now the second most affected country globally. Faced with this scenario, various public health measures and change...
Betacoronavirus,
Brasil/epidemiología,
COVID-19,
Carcinoma Hepatocelular/epidemiología,
Carcinoma Hepatocelular/terapia,
Consenso,
Infecciones por Coronavirus,
Neoplasias Hepáticas/epidemiología,
Neoplasias Hepáticas/terapia,
Pandemias,
Neumonía Viral,
SARS-CoV-2
OBJECTIVES: Previous studies focusing on pediatric patients hospitalized with severe coronavirus disease 2019 (COVID-19) have been limited to small case series. We aimed to evaluate the characteristics of a large population of pediatric patients with severe COVID-19 and compare them with patients with se...
Abstract The spread of Coronavirus is causing in the society all around the world a considerable degree of fear, worry and concern and particularly among healthcare workers that are at increased risk for infection. This paper gathers the strategy/guidelines to reduce the contamination in Intensive care u...
