ABSTRACT Purpose To determine enzymatic antioxidant and lipid peroxidation levels in seminal plasma of patients orchiectomized for testicular tumors. Materials and Methods The study included 52 patients: 26 control men and 26 orchiectomized patients for testicular tumor, of which 12 men had seminoma ...
Antioxidantes/metabolismo,
Estudios de Casos y Controles,
Catalasa/metabolismo,
Estudios Transversales,
Glutatión Peroxidasa/metabolismo,
Peroxidación de Lípido/fisiología,
Persona de Mediana Edad,
Oligospermia,
Orquiectomía,
Estrés Oxidativo/fisiología,
Semen/enzimología,
Análisis de Semen,
Seminoma/metabolismo,
Recuento de Espermatozoides,
Superóxido Dismutasa/metabolismo,
Neoplasias Testiculares/metabolismo,
Neoplasias Testiculares/cirugía
Abstract INTRODUCTION: We compared indicators of oxidative stress in the tissue of mice infected with strains from Sporothrix schenckii complex. METHODS: Mice were inoculated with Sporothrix brasiliensis, Sporothrix schenckii sensu stricto, Sporothrix globosa, Sporothrix mexicana or Sporothrix albica...
ABSTRACT Purpose: We evaluated dynamic thiol/disulfide homeostasis (TDH), malondialdehyde (MDA) levels, and catalase (CAT) activity in patients with age-related macular degeneration (AMD). All analyzes were conducted on plasma samples. Methods: Thirty-two patients with AMD and 38 age-matched healthy co...
Factores de Edad,
Antioxidantes,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Catalasa/metabolismo,
Disulfuros/sangre,
Homeostasis,
Degeneración Macular/sangre,
Malondialdehído/sangre,
Estrés Oxidativo/fisiología,
Compuestos de Sulfhidrilo/sangre
Abstract Metallothioneins are a superfamily of low-molecular-weight, cysteine (Cys)-rich proteins that are believed to play important roles in protection against metal toxicity and oxidative stress. The main purpose of this study was to investigate the effect of heterologous expression of a rice metallot...
Cadmio/metabolismo,
Etanol/metabolismo,
Expresión Génica,
Peróxido de Hidrógeno/metabolismo,
Metalotioneína/genética,
Metalotioneína/metabolismo,
Oryza/genética,
Estrés Oxidativo,
Proteínas de Plantas/genética,
Proteínas de Plantas/metabolismo,
Isoformas de Proteínas/genética,
Isoformas de Proteínas/metabolismo,
Saccharomyces cerevisiae/genética,
Saccharomyces cerevisiae/metabolismo
Abstract Purpose: To evaluate the pulmonary oxidative stress in diabetic rats exposed to hyperoxia for 90 minutes. Methods: Forty male Wistar rats were divided into four groups, each one containing 10 animals, according to the oxygen concentration to which they were exposed: 21%, 50%, 75% and 100% (hyp...
O carcinoma cutâneo é a neoplasia maligna mais frequente na população brasileira, correspondendo a cerca de 25% de todas as lesões malignas registradas no País. Embora represente apenas cerca de 5% dos casos de câncer de pele, o melanoma provoca a maioria das mortes por malignidades cutâneas, pel...
Abstract Stress tolerance is a key attribute that must be considered when using yeast cells for industrial applications. High temperature is one factor that can cause stress in yeast. High environmental temperature in particular may exert a natural selection pressure to evolve yeasts into thermotolerant ...
Antioxidantes/metabolismo,
Kluyveromyces/fisiología,
Estrés Oxidativo,
Saccharomyces cerevisiae/fisiología,
Estrés Fisiológico,
Biomasa,
Catalasa/análisis,
Membrana Celular/química,
Ácidos Grasos/análisis,
Calor,
Kluyveromyces/química,
Kluyveromyces/crecimiento & desarrollo,
Kluyveromyces/efectos de la radiación,
Peroxidación de Lípido,
Especies Reactivas de Oxígeno/metabolismo,
Saccharomyces cerevisiae/química,
Saccharomyces cerevisiae/crecimiento & desarrollo,
Saccharomyces cerevisiae/efectos de la radiación
BISPO, VANDERSON S;
DANTAS, LUCAS S;
CHAVES FILHO, ADRIANO B;
PINTO, ISABELLA F D;
SILVA, RAILMARA P DA;
OTSUKA, FELIPE A M;
SANTOS, RODRIGO B;
SANTOS, ALINE C;
TRINDADE, DANIELLE J;
MATOS, HUMBERTO R.
ABSTRACT Hepatic disorders such as steatosis and alcoholic steatohepatitis are common diseases that affect thousands of people around the globe. This study aims to identify the main phenol compounds using a new HPLC-ESI+-MS/MS method, to evaluate some oxidative stress parameters and the hepatoprotective ...
Antioxidantes/farmacología,
Ácido Ascórbico/farmacología,
Ácidos Cafeicos/farmacología,
Colesterol/sangre,
Cocos/química,
Daño del ADN/efectos de los fármacos,
Etanol/farmacología,
Peroxidación de Lípido,
Hígado/efectos de los fármacos,
Hígado/metabolismo,
Estrés Oxidativo/efectos de los fármacos,
Ratas Wistar,
Reproducibilidad de los Resultados,
Espectrometría de Masas en Tándem,
Sustancias Reactivas al Ácido Tiobarbitúrico,
Factores de Tiempo,
Triglicéridos/sangre,
Agua/farmacología
ABSTRACT Background: Oxidative stress may aggravate symptoms of hemolytic anemias such as beta-thalassemia. FoxO3 activation results in resistance to oxidative stress in fibroblasts and neuronal cell cultures. Objective: The purpose of this research was to study FoxO3 gene expression and oxidative stat...
ABSTRACT Objectives The aim of this prospective clinical study was to investigate variations in a novel oxidative stress marker (thiol/disulphide homeostasis) in men who underwent transrectal ultrasound guided prostate biopsy (TRUSB). Materials and Methods A total of 22 men undergoing TRUSB of the pr...
Biomarcadores,
Biopsia,
Tacto Rectal,
Disulfuros/metabolismo,
Biopsia por Aspiración con Aguja Fina Guiada por Ultrasonido Endoscópico,
Biopsia Guiada por Imagen,
Estrés Oxidativo,
Estudios Prospectivos,
Próstata/patología,
Antígeno Prostático Específico/metabolismo,
Neoplasias de la Próstata/diagnóstico por imagen,
Neoplasias de la Próstata/metabolismo,
Compuestos de Sulfhidrilo/metabolismo,
Ultrasonografía