Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically man...
Biopsia,
Resultado Fatal,
Neoplasias Hepáticas/patología,
Neoplasias Pulmonares/patología,
Melaninas/orina,
Melanoma/complicaciones,
Melanoma/patología,
Melanoma/secundario,
Melanosis/etiología,
Melanosis/patología,
Melanosis/orina,
Piel/patología,
Neoplasias Cutáneas/complicaciones,
Neoplasias Cutáneas/patología,
Neoplasias Cutáneas/secundario
Abstract: Blue nevus is a benign melanocytic lesion, typically asymptomatic and of unknown etiology. Many histological subtypes are recognized, the most commons being: common blue nevus, cellular blue nevus, and combined blue nevus. New rare variants have been described in the literature, with emphasis o...
Abstract Woolly hair nevus is a rare condition characterized by a structural anomaly of the hair, restricted to certain areas of the scalp. The hair becomes coiled and slightly hypopigmented. The term woolly hair refers to changes that affect all the scalp and has a hereditary character. We present a cas...
Abstract: On rare occasions, skin lesions are the first local of metastatic manifestation of internal malignancies. In case of no previous diagnosis of these tumors, the approach of suspicious skin lesions becomes a challenge, especially in differentiating cutaneous metastases and adnexal primary neoplas...
Abstract The coiled and dotted vessels in a serpiginous arrangement or "string of pearls" is considered a classical vascular pattern associated with clear cell acanthoma. We present three cases of epidermal tumors different from clear cell acanthoma that have the same "string of pearls" vascular pattern....
Abstract: Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. Thi...
Abstract Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant manifestation of cutaneous and uterine leiomyomas together with renal cancer due to autosomal dominant germline mutations of fumarate hydratase gene. A twenty-year-old female patient presented with type-II segmen...
Edad de Inicio,
Biopsia,
Fumarato Hidratasa/genética,
Inmunohistoquímica,
Leiomiomatosis/genética,
Leiomiomatosis/patología,
Síndromes Neoplásicos Hereditarios/genética,
Síndromes Neoplásicos Hereditarios/patología,
Piel/patología,
Neoplasias Cutáneas/genética,
Neoplasias Cutáneas/patología,
Tumor de Músculo Liso/patología,
Neoplasias Uterinas/genética,
Neoplasias Uterinas/patología
Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis...
Biopsia,
Linfocitos T CD8-positivos/patología,
Hiperpigmentación/tratamiento farmacológico,
Hiperpigmentación/patología,
Inmunohistoquímica,
Micosis Fungoide/tratamiento farmacológico,
Micosis Fungoide/patología,
Terapia PUVA/métodos,
Neoplasias Cutáneas/tratamiento farmacológico,
Neoplasias Cutáneas/patología,
Resultado del Tratamiento
Objetivos: As neoplasias malignas de pele constituem a maior parte dos cânceres no Brasil e no mundo. O presente estudo tem o objetivo de realizar uma revisão sobre as principais características das neoplasias malignas de pele e que auxilie na prática médica.
Métodos: Este é um estudo de revisão ...
Contexto: A ciclosporina é um potente imunossupressor que age primariamente nas células T por meio da inibição da calcineurina e consequente inibição da transdução do sinal mediada pela ativação do receptor das células T, sendo considerada por muitos como terapia de escolha nos casos de dermat...
