Castoldi, Robson Chacon;
Manganaro, Lincoln José;
Ferreira, Soraia Carolline;
Alves, Marcelo José;
De-Carvalho-Filho, Carlos Augusto;
Garcia, Thiago Alves;
Ozaki, Guilherme Akio Tamura;
Caetano, Heliard Rodrigues dos Santos;
Zanuto, Éverton Alex Carvalho;
Giometti, Inês Cristina;
Camargo-Filho, José Carlos Silva.
The indiscriminate use of anabolic steroids in gyms has been growing in a generalized way, among which, the most common is growth hormone (GH). In the short term GH may potentiate muscle growth, especially when taken in combination with resistance training. However, the effects of this hormone are not ye...
Bone metabolism disorders are characterized by an imbalance of bone resorption and formation in the bone
remodeling process. Glucocorticoids that are used to treat kidney diseases exacerbate these disorders. P-selectin and galectin-3 are molecules involved in the sclerotic process in kidney, whereas bone...
Densidad Ósea/efectos de los fármacos,
Enfermedades Óseas Metabólicas/diagnóstico,
Enfermedades Renales/fisiopatología,
Enfermedades Renales/tratamiento farmacológico,
Galectina 3/efectos de los fármacos,
Galectina 3/sangre,
Glucocorticoides/efectos adversos,
Ligando RANK/efectos de los fármacos,
Ligando RANK/sangre,
Osteoporosis/prevención & control,
Osteoprotegerina/efectos de los fármacos,
Osteoprotegerina/sangre,
Ratas Wistar,
Remodelación Ósea/efectos de los fármacos,
Selectina-P/efectos de los fármacos,
Selectina-P/sangre,
Trastorno Mineral y Óseo Asociado a la Enfermedad Renal Crónica/inducido químicamente,
Dexametasona/administración & dosificación,
Glicerol/administración & dosificación,
Cloroformo/uso terapéutico
ABSTRACT Objective: Urinary stones with oxalate composition can cause kidney failure. Recent findings evidenced that probiotics are effective in reducing oxalate absorption in these subjects based on their high colonic absorption levels at baseline. The purpose of this study was to evaluate the effect o...
Nitrógeno de la Urea Sanguínea,
Calcio/análisis,
Creatinina/análisis,
Hiperoxaluria/prevención & control,
Cálculos Renales/prevención & control,
Cálculos Renales/orina,
Túbulos Renales/química,
Oxalatos/orina,
Extractos Vegetales/farmacología,
Probióticos/farmacología,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Tribulus/química,
Urtica dioica/química
Abstract Smoking is one of the main risk factor for periodontal disease, increasing its prevalence and severity. Probiotics emerged as an alternative for the prevention and treatment of many diseases, since it can modulate the host immune response and modify the modify the microbiome. Therefore, the aim ...
Abstract Objective To analyze the effect of thalidomide on the progression of endometriotic lesions experimentally induced in rats and to characterize the pattern of cell proliferation by immunohistochemical Proliferating Cell Nuclear Antigen (PCNA) labeling of eutopic and ectopic endometrium. Methods...
Abstract Background: In view of the increased global prevalence of cardiovascular and hepatic diseases, the diet lipid content and its relationship with the accumulation of fat in hepatocytes have been investigated as key factors in preventing these diseases. Objective: To evaluate the metabolic effect...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Peso Corporal,
Colesterol/efectos adversos,
Colesterol/sangre,
HDL-Colesterol/sangre,
LDL-Colesterol/sangre,
Dieta Alta en Grasa/efectos adversos,
Grasas de la Dieta/efectos adversos,
Modelos Animales de Enfermedad,
Dislipidemias/sangre,
Dislipidemias/inducido químicamente,
Dislipidemias/metabolismo,
Hígado Graso/patología,
Inflamación,
Hígado/metabolismo,
Hígado/patología,
Enfermedades Metabólicas/sangre,
Enfermedades Metabólicas/etiología,
Enfermedades Metabólicas/metabolismo,
Tamaño de los Órganos,
Ratas Wistar,
Triglicéridos/sangre
Nascimento, Gildenisson Araújo do;
Souza, Diego Santos de;
Lima, Bruno Santos;
Vasconcelos, Carla Maria Lins de;
Araújo, Adriano Antunes de Souza;
Durço, Aimée Obolari;
Quintans-Junior, Lucindo José;
Almeida, Jackson Roberto Guedes da Silva;
Oliveira, Aldeída Pereira;
Santana-Filho, Valter Joviniano de;
Barreto, André Sales;
Santos, Márcio Roberto Viana dos.
Abstract Background: D-limonene (DL) is a monoterpene and is the major component in the essential oil of citrus fruit. It presents antihyperglycemic and vasodilatation activities. Objectives: This study evaluated the cardiovascular effects and potential antiarrhythmic of DL in rats. Methods: Hemodynam...
Antiarrítmicos/farmacología,
Antiarrítmicos/uso terapéutico,
Arritmias Cardíacas/inducido químicamente,
Arritmias Cardíacas/diagnóstico,
Arritmias Cardíacas/tratamiento farmacológico,
Presión Sanguínea/efectos de los fármacos,
Bradicardia/diagnóstico,
Bradicardia/tratamiento farmacológico,
Electrocardiografía,
Frecuencia Cardíaca/efectos de los fármacos,
Hemodinámica/efectos de los fármacos,
Hipotensión,
Preparación de Corazón Aislado,
Limoneno/farmacología,
Limoneno/uso terapéutico,
Modelos Animales,
Ratas Wistar,
Presión Ventricular/efectos de los fármacos
Abstract Purpose: To evaluate liver regeneration after selective ligation of portal vein and hepatic artery by 3D Computed Tomography in an experimental model. Methods: Sixteen Wistar rats were randomized into four equal groups: Group I- control (sham), Group II- isolated selective ligation of the hepa...
Arteria Hepática/cirugía,
Hepatomegalia/diagnóstico por imagen,
Hepatomegalia/fisiopatología,
Imagenología Tridimensional/métodos,
Inmunohistoquímica,
Ligadura,
Hígado/irrigación sanguínea,
Hígado/diagnóstico por imagen,
Hígado/patología,
Regeneración Hepática/fisiología,
Tamaño de los Órganos/fisiología,
Vena Porta/cirugía,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Tomografía Computarizada por Rayos X/métodos,
Resultado del Tratamiento
Nascimento, Lízia Daniela e Silva;
Nicolau, Renata Amadei;
Maia Filho, Antônio Luiz Martins;
Santos, José Zilton Lima Verde;
Fonseca, Khetyma Moreira;
Ferreira, Danniel Cabral Leão;
Sousa, Rayssilane Cardoso de;
Viana, Vicente Galber Freitas;
Carvalho, Luiz Fernando Meneses;
Figueredo-Silva, José.
Abstract Purpose: To determine the efficacy of norbixin-based poly(hydroxybutyrate) (PHB) membranes for Achilles tendon repair. Methods: Thirty rats were submitted to total tenotomy surgery of the right Achilles tendon and divided into two groups (control and membrane; n = 15 each), which were further ...
Tendón Calcáneo/efectos de los fármacos,
Tendón Calcáneo/patología,
Tendón Calcáneo/cirugía,
Carotenoides/farmacología,
Colágeno Tipo I/análisis,
Colágeno Tipo I/efectos de los fármacos,
Colágeno Tipo III/análisis,
Colágeno Tipo III/efectos de los fármacos,
Fibroblastos/efectos de los fármacos,
Hidroxibutiratos/farmacología,
Poliésteres/farmacología,
Ratas Wistar,
Valores de Referencia,
Regeneración/efectos de los fármacos,
Reproducibilidad de los Resultados,
Tenotomía/métodos
Objective: Chemotherapy treatment against cancer produce systemic toxicities, among which are those related to important structures of the stomatognathic system and its functional activity. 5 Fluorouracil (5-FU) and cyclophosphamide (Cf) are drugs widely used in solid tumors and in bone marrow transplant...
