Results: 1341

Inhibition of symbiote fungus of the leaf cutter ant Atta sexdens by secondary metabolites from the bacterium Xenorhabdus szentirmaii associated with entomopathogenic nematodes

Arq. Inst. Biol; 85 (), 2018
Leaf-cutter ants (Hymenoptera: Formicidae) have evolved as dominant herbivores on the American continent. These social insects remove the leaves of economically important plant species to maintain their colony’s food reserves, the symbiotic fungus Leucocoprinus gongylophorus, a basidiomycete. Such fung...

Bacterias: ¿Por qué me enferman?

Bacterias, ¿Por qué me enferman? Es un libro que pretende acercarnos al diminuto e invisible mundo de los microorganismos con los que convivimos día a día y con quienes interactuamos constantemente, muchas veces sin darnos cuenta. Este texto entrega material exploratorio y de divulgación científica...

Human polyomaviruses and cancer: an overview

Clinics; 73 (supl.1), 2018
The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the capacity of mediating cell transformation and tumo...

Influência de TLR3 em modelo de Paracoccidioidomicose experimental

Os receptores do tipo Toll compreendem a família de receptores de reconhecimento de padrões melhor caracterizados, que podem ativar diferentes respostas imunes, dependendo de quais receptores e conjuntos de adaptadores são utilizados. Os TLRs, como TLR2, TLR4 e TLR9, e sua sinalização foram implicad...

Busca por inibidores seletivos de Sirtuína 2 de T. cruzi empregando técnicas de planejamento de fármacos baseadona estrutura do receptor

A doença de Chagas, causada pelo parasita Trypanosoma cruzi, acomete entre 6 a 8 milhões de pessoas em todo o mundo. Conhecida como tripanossomíase americana, por ter sido considerada endêmica apenas na América Latina, esta doença, se espalhou para outros continentes devido aos movimentos migratór...

Avaliação da imunogenicidade de diferentes formas alélicas da proteí­na recombinante PvAMA-1expressa em Pichia pastoris: impacto da diversidade antigênica

A malária é um problema de saúde pública no Brasil e no mundo. Em 2016, o número de casos estimado pela Organização Mundial de Saúde foi de 216 milhões. Plasmodium falciparum é a espécie mais prevalente e responsável pelo maior número de mortes no mundo, sobretudo no continente africano. Por...

Optimization of the yield of bacteriocin-like substance (BLIS) produced by Pediococcus pentosaceus and its application as food bioconservative

Bacteriocins are peptides produced by various species of bacteria, especially lactic acid bacteria (LABs), which exhibit a large spectrum of action against spoilage bacteria and foodborne pathogens. However, when this bacteriocin has not been completely characterized regarding its amino acid and the nucl...

Introns in Cryptococcus

Mem. Inst. Oswaldo Cruz; 113 (7), 2018
In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regula...

Intestinal cell migration damage induced by enteropathogenic Escherichia coli strains

Braz. j. med. biol. res; 51 (10), 2018
Epithelial cell migration is an essential response to enteric pathogens such as enteropathogenic Escherichia coli (EPEC). This study aimed to investigate the effects of EPEC infection on intestinal epithelial cell migration in vitro, as well as the involvement of type III secretion system (T3SS) and Rho ...

In-vivo evaluation of pathogenicity and antimicrobial profile susceptibility from Escherichia coli samples isolated from commercial layer hens

Arq. Inst. Biol; 85 (), 2018
Antimicrobial sensitivity and pathogenicity level of 90 strains of Escherichia coli isolated from livers and intestines from commercial layer hens presenting diarrhea were analyzed. To evaluate the antimicrobial susceptibility, all samples were subjected to antimicrobial susceptibility testing using 11 ...