Abstract INTRODUCTION This aim of this study was to evaluate the antibacterial activity of fractions and isolates of Maytenus guianensis, a plant species used in Amazonian folk medicine. METHODS A disk diffusion technique was used to investigate the antibacterial potential. RESULTS The hexanic frac...
Abstract There are several controversies regarding the efficacy of homeopathic substances; however, these remedies are used in many countries for the treatment of various pathological conditions. The purpose of this study was to evaluate the in vitro antibacterial activity of two homeopathic tinctures Ar...
Introdução: o uso de Morinda citrifolia (noni) realizado com várias finalidades, no entanto, sua eficácia ainda não é, plenamente, comprovada. Segundo a Agência Nacional de Vigilância Sanitária (2007), as publicações científicas sobre o suco de noni têm trazido muita controvérsia sobre sua ...
Lippia graveolens Kunth (Verbenaceae) is an economically important shrub known in Mexico as Oregano. In this work, the biocidal effect of the hexane extract of L. graveolens leaves was evaluated on two crop pests. Thus, larvae of Spodoptera frugiperda were fed with mixtures of extract and artificial diet...
Control Biológico de Vectores,
Lippia/química,
Hojas de la Planta/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Verbenaceae,
Larva,
Cromatografía de Gases/métodos,
Espectroscopía de Resonancia Magnética,
Spodoptera/efectos de los fármacos,
Antinematodos/farmacología,
Antinematodos/química,
Monoterpenos/análisis,
Fenoles/análisis
This study analysed the total content of phenolic compounds in roots and rhizomes extracts from two populations of Valeriana carnosa Sm. (Caprifoliaceae) at three phenological stages. Total phenolic content was determined through the Folin-Ciocalteu method, which ranged between individuals from 3.56 to 1...
Abstract Purpose: To investigate the gastroprotective effect of methanol extract of E. spectabilis and its major component isoorientin. Methods: Effects of isoorientin and methanol extract of E. spectabilis were investigated in indomethacin-induced gastric damage model on rats. Famotidine was used as...
Antiulcerosos/farmacología,
Antioxidantes/farmacología,
Relación Dosis-Respuesta a Droga,
Glutatión/análisis,
Glutatión/efectos de los fármacos,
Indometacina,
Luteolina/farmacología,
Malondialdehído/análisis,
Metanol/farmacología,
Extractos Vegetales/farmacología,
Ratas Wistar,
Reproducibilidad de los Resultados,
Índice de Severidad de la Enfermedad,
Úlcera Gástrica/tratamiento farmacológico,
Úlcera Gástrica/patología,
Superóxido Dismutasa/análisis,
Superóxido Dismutasa/efectos de los fármacos,
Resultado del Tratamiento,
Asphodelaceae/química
ABSTRACT The hemoflagellate protozoan, Trypanosoma cruzi, mainly transmitted by triatomine insects through blood transfusion or from mother-to-child, causes Chagas' disease. This is a serious parasitic disease that occurs in Latin America, with considerable social and economic impact. Nifurtimox and benz...
Electroforesis en Gel Bidimensional,
Espectrometría de Masas,
Estrés Oxidativo,
Piperidonas/farmacología,
Extractos Vegetales/farmacología,
Proteínas/análisis,
Proteómica,
Valores de Referencia,
Reproducibilidad de los Resultados,
Tripanocidas/farmacología,
Trypanosoma cruzi/química,
Trypanosoma cruzi/efectos de los fármacos,
Trypanosoma cruzi/metabolismo
Objective: The harmful use of psychoactive substances represents one of today's largest public health problems. Yet, in spite of its global relevance, current treatment for substance use disorders (SUDs) is still not entirely successful. The purpose of this study was to investigate alternative treatments...
Abstract The study of metabolomics requires extracting as many metabolites as possible from a biological sample. This study aimed to determine the optimal method for the extraction of metabolites from solid-state fermented cottonseed meal (FCSM). The UPLC-Q-TOF-MS global metabolomics technology was used ...
Oliveira, Flávio Augusto de Souza;
Passarini, Guilherme Matos;
Medeiros, Daniel Sol Sol de;
Santos, Ana Paula de Azevedo;
Fialho, Saara Neri;
Gouveia, Aurileya de Jesus;
Latorre, Marcinete;
Freitag, Elci Marlei;
Medeiros, Patrícia Soares de Maria de;
Teles, Carolina Bioni Garcia;
Facundo, Valdir Alves.
Abstract INTRODUCTION This study assessed the activity of compounds from Piper tuberculatum against Plasmodium falciparum and Leishmania guyanensis. METHODS The effects of compounds from P. tuberculatum fruits on P. falciparum and L. guyanensis promastigote growth in vitro were determined. Hemolytic ...
