Results: 1181

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma

An. bras. dermatol; 94 (1), 2019
Abstract: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this procedure. Objective: To evaluate the association ...

Low levels of dehydroepiandrosterone sulfate are associated with the risk of developing cardiac autonomic dysfunction in elderly subjects

ABSTRACT Objective: To assess the relationships between serum dehydroepiandrosterone sulfate (DHEA-S) levels and heart rate variability (HRV) among different age groups. Subjects and methods: Forty-five healthy men were divided into 3 groups: young age (YA; 20-39 yrs; n = 15), middle age (MA; 40-59 yrs...

Challenges and lessons from a primary care intervention in a Brazilian municipality

ABSTRACT OBJECTIVE To address the implementation of the Lab for Innovation in Chronic Conditions in Santo Antonio do Monte, indicating the main challenges and lessons of a new chronic condition model. METHODS This is an observational study based on two sources of data: 1) two cross-sectional househol...

Predictive model of unfavorable outcomes for multidrug-resistant tuberculosis

ABSTRACT OBJECTIVE to analyze the temporal trend, identify the factors related and elaborate a predictive model for unfavorable treatment outcomes for multidrug-resistant tuberculosis (MDR-TB). METHODS Retrospective cohort study with all cases diagnosed with MDR-TB between the years 2006 and 2015 in ...

The ability of waist-to-height ratio to identify health risk

ABSTRACT OBJECTIVE To evaluate the performance of the ratio between the waist circumference and the height in the identification of health risk compared with the correlation matrix between the anthropometric parameters body mass index and waist circumference. METHODS A population-based study presenti...

Mental disorders and suicide risk in emerging adulthood: the 1993 Pelotas birth cohort

ABSTRACT OBJECTIVE To assess the prevalence of some mental disorders and suicide risk, and the association between them in youths. METHODS Data from the 1993 Pelotas Birth Cohort (Brazil) was used. The prevalence of mental disorders at 22 years [major depressive disorder (MDD), generalized anxiety di...

Prevalence and co-occurrence of modifiable risk factors in adults and older people

ABSTRACT OBJECTIVE To estimate the co-occurrence of the major risk factors for chronic diseases in adults (18-59 years old) and older people (≥ 60 years old) living in Brazilian state capitals and the Federal District. METHODS Cross-sectional study with population-based data from 35,448 adults ...

Cardiorespiratory fitness associated to teenagers' fat: vo2max cutoff point

ABSTRACT Objective: To associate the Maximal Oxygen Uptake (VO2max) with body fat percentage (%BF), and to establish the best VO2max cutoff point for predicting risk %BF in teenagers. Methods: This study was carried out with 979 subjects aged 10 to 18.8 years, 556 (56.8%) girls. The 20 m shuttle run ...

A systematic review on the influence of hla-b polymorphisms on hiv-1 mother-to-child-transmission

Braz. j. infect. dis; 23 (1), 2019
ABSTRACT Background: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection. Objective: To evaluate which polymorphisms of HLA-B are involved in...

Avaliação da presença do 3-monocloro-1, 2-propanediol e glicidol em óleos vegetais comestíveis utilizando GC/MS/MS e seu risco toxicológico

Cloropropanóis são um grupo conhecido de contaminantes relacionados ao processamento de alimentos. Eles são formados na reação entre lipídeos e cloretos quando submetidos ao tratamento térmico, e podem ser encontrados na forma livre ou ligada. O 3-monocloro-1,2-propanediol (3-MCPD), é classificad...