We report an asymptomatic 23-year-old woman with an isolated and persistent increase in serum levels of aspartate aminotransferase (AST). An extensive work up including laboratory and image testing revealed no abnormalities thus suggesting the presence of macro-AST. A polyethylene glycol (PEG) precipitat...
Objective Thyroid disease affects 6.6% of the general population. The liver is fundamental in metabolizing thyroid hormones, and hepatocytes are often affected in thyroid disease. We aimed to compare clinical and laboratory parameters among thyroid disease patients with alanine aminotransferase (ALT) le...
Alanina Transaminasa/sangre,
Índice de Masa Corporal,
Colesterol/sangre,
Estudios Transversales,
Dislipidemias/sangre,
Hipertensión/sangre,
Hepatopatías/sangre,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Enfermedades de la Tiroides/sangre,
Tirotropina/sangre,
Circunferencia de la Cintura
BACKGROUND: Carbon tetrachloride (CCl4) induces hepatotoxicity in animal models, including the increased blood flow and cytokine accumulation that are characteristic of tissue inflammation. The present study investigates the hepato-protective effect of rutin on CCl4-induced hepatotoxicity in rats. RESULT...
Enfermedad Hepática Inducida por Sustancias y Drogas/tratamiento farmacológico,
Interleucina-6/metabolismo,
Rutina/farmacología,
Factor de Transcripción STAT3/metabolismo,
Transducción de Señal/efectos de los fármacos,
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Factor de Crecimiento Epidérmico/metabolismo,
Proteína de Dominio de Muerte Asociada a Fas/metabolismo,
Expresión Génica/efectos de los fármacos,
Quinasas Janus/metabolismo,
Hígado/efectos de los fármacos,
MAP Quinasa Quinasa 5/metabolismo,
Sustancias Protectoras/farmacología,
Proteínas Proto-Oncogénicas c-bcl-2/metabolismo,
Proteína bcl-X/metabolismo,
Biomarcadores,
Tetracloruro de Carbono,
Ratas Wistar,
Reacción en Cadena en Tiempo Real de la Polimerasa
BACKGROUND: In the last decades, overweight and obesity have been transformed from minor public health issues to a major threat to public health affecting the most affluent societies and also the less developed ones. OBJECTIVES: To estimate overweight-obesity prevalence in adults, their association with ...
Estilo de Vida,
Sobrepeso/epidemiología,
Distribución por Edad,
Factores de Edad,
Alanina Transaminasa/Sangre,
Consumo de Bebidas Alcohólicas/efectos adversos,
Consumo de Bebidas Alcohólicas/epidemiología,
Biomarcadores/Sangre,
Glucemia/análisis,
Índice de Masa Corporal,
Colesterol/Sangre,
Métodos Epidemiológicos,
Italia/epidemiología,
Obesidad/Sangre,
Obesidad/epidemiología,
Sobrepeso/Sangre,
Distribución por Sexo,
Factores Socioeconómicos,
Triglicéridos/Sangre
We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-alpha (IFN-alpha) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-alpha. At the end of therapy there was an e...
Introduçao. A hepatite crônica pelo vírus C apresenta tendência evolutiva para cirrose hepática e hepatocarcinoma. Tratamento, com drogas antivirais, está indicado numa tentativa de modificar a evoluçao da doença. Objetivo. Avaliar a resposta de pacientes com hepatite crônica ou cirrose pós-hep...
Trabalhos anteriores sugerem a oclusäo supra-celíaca no tratamento cirúrgico dos aneurismas da aorta abdominal de dificil abordagem. Com o objetivo de estudar as repercussöes metabólicas hepáticas e renais, três grupos de cäes foram submetidos à oclusäo temporária (30 minutos) da aorta abdomin...
Se evaluaron 973 donantes voluntarios del Centro Nacional de Sangre en Tegucigalpa, por la presencia de anticuerpos contra el virus de la Hepatitis C (Anti-VHC); anticuerpos contra el núcleo del virus de la Hepatitis B (Anti-HBc), contra el antígeno de superficie (Anti-HBc), contra el Antígeno de Supe...
Objetivo: Avaliação da eficácia e tolerabilidade da sinvastatina, um novo e potente inibidor da HMGCoA redutase, no tratamento da hipercolesterolemia em pacientes idosos. Casuística e Métodos: Foram estudados 20 pacientes com idades entre 65 e 72 anos (x = 69 ± 3), sendo 14 mulheres e 6 homens, com...
