We report a 45-year-old male with AIDS who had a Cryptococcus neoformans central nervous system infection. He was treated with amphotericin B deoxycholate subsequently changed to voriconazole due to systemic toxicity of the former. Plasma levels of voriconazole were insufficient with a standard dose (0.7...
Infecciones Oportunistas Relacionadas con el SIDA/tratamiento farmacológico,
Anfotericina B/efectos adversos,
Antifúngicos/efectos adversos,
Ácido Desoxicólico/efectos adversos,
Síndrome Inflamatorio de Reconstitución Inmune/inducido químicamente,
Meningitis Criptocócica/tratamiento farmacológico,
Voriconazol/administración & dosificación,
Infecciones Oportunistas Relacionadas con el SIDA/diagnóstico por imagen,
Anfotericina B/administración & dosificación,
Antifúngicos/administración & dosificación,
Ácido Desoxicólico/administración & dosificación,
Combinación de Medicamentos,
Meningitis Criptocócica/diagnóstico por imagen
Abstract Introduction Otomycosis is a common problem in otolaryngology practice. However, we usually encounter some difficulties in its treatment because many patients show resistance to antifungal agents, and present high recurrence rate. Objectives To determine the fungal pathogens that cause otomyco...
Otomicosis/microbiología,
Antifúngicos/farmacología,
Farmacorresistencia Fúngica,
Hongos/aislamiento & purificación,
Aspergillus/aislamiento & purificación,
Candida/aislamiento & purificación,
Voriconazol/farmacología,
Anfotericina B/farmacología,
Terbinafina/farmacología,
Itraconazol/farmacología,
Epidemiología Descriptiva,
Pruebas de Sensibilidad Microbiana,
Levaduras/aislamiento & purificación,
28573,
Aspergillus niger/aislamiento & purificación
Abstract Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study was to evaluate the antifungal effect of the combination of amp...
Mucormycosis is an infrequent fungal infection This infection is difficult to diagnose and treat and have a high morbility and mortality and affects immunocompromised patients, especially those patients with decompensated diabetes mellitus. We report the case of a 60 years old diabetic patient with poor ...
Resumen Presentamos el caso clínico de un paciente con una leucemia linfoblástica aguda (LLA) que desarrolló una fusariosis diseminada por Fusarium verticillioides durante un episodio prolongado de neutropenia febril post quimioterapia. Fue exitosamente tratado cuando se usó terapia combinada de vori...
Anfotericina B/uso terapéutico,
Antifúngicos/uso terapéutico,
Ácido Desoxicólico/uso terapéutico,
Fusariosis/tratamiento farmacológico,
Neutropenia/tratamiento farmacológico,
Voriconazol/uso terapéutico,
Combinación de Medicamentos,
Quimioterapia Combinada,
Fusariosis/etiología,
Fusariosis/patología,
Neutropenia/etiología,
Neutropenia/patología,
Leucemia-Linfoma Linfoblástico de Células Precursoras B/complicaciones,
Leucemia-Linfoma Linfoblástico de Células Precursoras B/tratamiento farmacológico,
Leucemia-Linfoma Linfoblástico de Células Precursoras B/microbiología
Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESU...
Infecciones Oportunistas Relacionadas con el SIDA/diagnóstico,
Infecciones Oportunistas Relacionadas con el SIDA/microbiología,
Anfotericina B/farmacología,
Antifúngicos/farmacología,
Brasil,
Candida/clasificación,
Candida/efectos de los fármacos,
Candida/aislamiento & purificación,
Candidiasis Bucal/diagnóstico,
Candidiasis Bucal/microbiología,
Farmacorresistencia Microbiana,
Fluconazol/farmacología,
Itraconazol/farmacología,
Pruebas de Sensibilidad Microbiana,
Persona de Mediana Edad,
Técnicas de Tipificación Micológica
Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis...
Abstract INTRODUCTION Pentavalent antimonials (Sbv) are the most commonly used drugs for the treatment of mucosal leishmaniasis (ML), despite their high toxicity and only moderate efficacy. The aim of this study was to report therapeutic responses with different available options for ML. METHODS This...
Abstract: The number of new cases of emerging fungal infections has increased considerably in recent years, mainly due to the large number of immunocompromised individuals. The objective of this study was to evaluate the susceptibility of emerging fungi to fluconazole, itraconazole and amphotericin B by ...
Anfotericina B/uso terapéutico,
Antifúngicos/farmacología,
Antifúngicos/uso terapéutico,
Farmacorresistencia Fúngica,
Fluconazol/uso terapéutico,
Hongos/efectos de los fármacos,
Hongos/aislamiento & purificación,
Infecciones por VIH/complicaciones,
Itraconazol/uso terapéutico,
Pruebas de Sensibilidad Microbiana,
Micosis/tratamiento farmacológico,
Micosis/microbiología
Leishmaniasis, a parasitic disease produced by a protozoan of the genus Leishmania, is triggered by the bite of an infected sandfly. It is endemic in tropical and
subtropical areas of the Americas, places of
poor socioeconomic health conditions and
malnutrition. These conditions favor the
entry of other ...
